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Summary of the endocrine system and hormones

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An in depth summary of the pituitary, adrenal glands and associated hormones.

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  • December 30, 2023
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  • 2023/2024
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HORMONES
Hypothalamus




 A small area of the brain found above the pituitary gland.
 Involved in controlling homeostasis and hormone release.
 It controls hormone release by controlling the pituitary gland.
Pituitary gland
 Seen as the master hormone as it secretes many hormones.
 Consists of 2 lobes: anterior and posterior pituitary
 Anterior synthesises hormones to be released around the body.
 The posterior pituitary doesn’t synthesise hormones, they are sent hormones from
the hypothalamus to secrete to the rest of the body.
Anterior pituitary: how are hormones released to the rest of the body?




 The hypothalamus releases “releasing hormones” from specialised neurones called
the neurosecretory cells.
 These travel down from the hypothalamus to the anterior lobe.
 They bind to receptors on the endocrine cells in the anterior lobe.
 This causes the synthesis and release of certain hormones.
 Which hormone is released depends on the type of releasing hormone.
 Examples of these releasing hormones include:
o gonadotropin-releasing hormone (GnRH)
o corticotropin-releasing hormone (CRH)
o thyrotropin-releasing hormone (TRH)
o growth hormone-releasing hormone (GHRH)
o and dopamine (prolactin-inhibiting hormone)

Anterior pituitary: what hormones are produced?
Remember FLAT PiG (silent i)
FSH: follicle-stimulating hormone which is for growth and reproduction.

, LH: luteinizing hormone is for testosterone production and reproduction.
ACTH: adrenocorticotropic hormone is for stress and fear responses.
TSH: thyroid stimulating hormone for metabolism.
GH: growth
Prolactin: promotes milk production in females.

Posterior pituitary hormones, roles and how they are released.
 The posterior pituitary is an extension of the hypothalamus.
 Magnocellular neurones run down towards the lobe.
 These neurons contain the genetic instructions and necessary machinery to produce
these peptide hormones.
 Once synthesized, oxytocin and vasopressin are transported down the axons of these
neurons.
 stored in nerve endings located in the posterior pituitary gland.
 to be released to the rest of the body.
 Oxytocin: contraction of the uterus during childbirth
 Anti-diuretic hormone/vasopressin: urine output and regulates blood pressure.

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