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WGU Biochemistry OA – Questions & Solutions

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WGU Biochemistry OA – Questions & Solutions

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  • December 19, 2023
  • 16
  • 2023/2024
  • Exam (elaborations)
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WGU Biochemistry OA – Questions & Solutions
Bohr Effect chart (low pH) ✔️Ans - C- High CO2
H- High H+
A- Acidic
R-Release of O2(rt. Shift)
T- tense state (in tissues)

Primary structure ✔️Ans - Sequence of amino acids that make up a
protein

Secondary Structure ✔️Ans - Sequence of amino acids fold.

Tertiary Structure ✔️Ans - -more folding in a 3D shape.
-R groups (side chains)

Quaternary Structure ✔️Ans - Protein has more than 1 polypeptide chain.

Chemical reaction ✔️Ans - -absorb and release energy
-activation energy
-energy is released (heat & light) when bonds are broken.

Exothermic reaction ✔️Ans - Exo=to release
Thermo=heat
-chemical reaction that releases more energy than it absorbs (as heat & light)

Example of exothermic reaction ✔️Ans - Cellular respiration- breaks
down glucose to make cellular energy

Endothermic reaction ✔️Ans - Endo=absorb
Thermos=heat
-absorbs more energy than it releases

Example of endothermic reaction ✔️Ans - Photosynthesis- takes in light
to break down to create glucose

Catalyst ✔️Ans - Substance that will decrease the activation energy
needed to start a chemical reaction

,Enzymes ✔️Ans - -catalysts used by cells
-increase the rate of chemical reaction
-specific to substrates

Enzyme structure ✔️Ans - -they are proteins
-twist, fold, bend to final shape
-shape attracts specific molecules

Substrate ✔️Ans - Molecules that bind to the enzyme

Active site ✔️Ans - -location on enzyme where substrate binds

Function of DNA polymerase in process of PCR. ✔️Ans - -increase
expression
-2 genes
-SIRT1 & SIRT2

Function of a molecule ✔️Ans - Structural component of the lipid bilayer

How would lipid production in a cell change in order to maintain fluidity of its
cell membrane as it adapts to lower temperatures? ✔️Ans - Produce
lipids with shorter fatty acid chains

Function of cholesterol ✔️Ans - Maintains membrane fluidity

Lipid (fat) soluble vitamins ✔️Ans - A, D, E, K

What stimulates beta-oxidation of fatty acids? ✔️Ans - An increase in
NAD+ concentration in the mitochondrial matrix

What occurs in an otherwise healthy person whose diet has very few carbs
and high levels of fats? ✔️Ans - Acetone is produced in the blood

Amino acids ✔️Ans - -Non-polar (hydrophobic)
-Polar charged
-Polar uncharged

, Which type of mammalian DNA damage repair requires the presence of the
chromosome that is homologous to the damaged chromosome? ✔️Ans -
Recombination

Xeroxerma Pigmentosum (XP) ✔️Ans - A recessive genetic disease that
occurs when one or more of the genes that perform nucleotide excision repair
are nonfunctional

Why do XP patients have a much higher incidence of skin cancer than the
general population? ✔️Ans - The mutation of all other genes is higher due
to failure to repair.

Assuming 100% reaction efficiency, how many DNA copies are created after
the completion of 4 complete PCR cycles? ✔️Ans - 16

What is the function of DNA polymerase in the process of PCR? ✔️Ans - It
recognizes the primers and uses the available dNTPs to replicate the template
DNA sequence.

What difference in the regions of the SIRT1 & SIRT2 genes in people addicted
to cocaine increases their expression? ✔️Ans - The nucleosomes become
more widely spaced.

What occurs during the process of alternative splicing of RNA? ✔️Ans -
Alternate combinations of Exons within the same gene are linked together.

Polypeptides ✔️Ans - -functional proteins
-made of folded up polymers

Elements ✔️Ans - Substance that cannot be broken down into another
substance by chemical reaction.

Ionic bond ✔️Ans - Actions share + & - charge

Covalent bond ✔️Ans - When atoms share electrons

Hydrogen bond ✔️Ans - Forms when portion of a polar molecule that is
partially positive interacts with portion of a polar molecule that is partially
negative

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