2023 Mn553 mn553 advanced pharmacology ph
armacotherapeutics ALL units quiz questions an
swers
Chapter 1. The Role of the Nurse Practitioner
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Nurse practitioner prescriptive authority is regulated by:
1 The National Council of State Boards of Nursing
.
2 The U.S. Drug Enforcement Administration
.
3 The iState iBoardiofiNursingifor ieachistate
.
4 The State Board of Pharmacy
.
2. The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber include:
1 Nurses know more about Pharmacology than other prescribers because they take
. it both in their basic nursing program and in their APRN program.
2 Nurses icare ifor itheipatient ifromiaiholistic iapproach iandiincludeitheipatient iin
. decisionimakingiregardingitheir icare.
3 APRNs are less likely to prescribe narcotics and other controlled substances.
.
4 APRNs are able to prescribe independently in all states, whereas a physician’s
. assistant needs to have a physician supervising their practice.
3. Clinical judgment in prescribing includes:
1 Factoringiinitheicost itoitheipatient iofitheimedicationiprescribed
.
2 Always prescribing the newest medication available for the disease process
.
3 Handing out drug samples to poor patients
.
, 4 Prescribing all generic medications to cut costs
.
4. Criteria for choosing an effective drug for a disorder include:
1. Asking the patient what drug they think would work best for them
2. Consultinginationallyirecognizediguidelines ifor idisease imanagement
3. Prescribing medications that are available as samples before writing a
prescription
4. Following U.S. Drug Enforcement Administration guidelines for prescribing
5. Nurse practitioner practice may thrive under health-care reform because of:
1 The idemonstrated iabilityiof inurseipractitioners itoicontrol icosts iandiimprove
patient ioutcomes
2 The fact that nurse practitioners will be able to practice independently
.
3 The fact that nurse practitioners will have full reimbursement under health-care
. reform
4 The ability to shift accountability for Medicaid to the state level
.
Chapter 2. Review of Basic Principles of Pharmacology
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. A patient’s nutritional intake and laboratory results reflect hypoalbuminemia. This is critical to prescribing because:
1 Distributioniofidrugs itoitarget itissue imayibeiaffected.
, 2 The solubility of the drug will not match the site of absorption.
.
3 There will be less free drug available to generate an effect.
.
4 Drugs bound to albumin are readily excreted by the kidneys.
.
2. Drugs that have a significant first-pass effect:
1 Must be given by the enteral (oral) route only
.
2 Bypass the hepatic circulation
.
3 Are irapidlyimetabolizedibyitheiliver iandimayihave ilittle iifianyidesirediaction
.
4 Are converted by the liver to more active and fat-soluble forms
.
3. The route of excretion of a volatile drug will likely be the:
1 Kidneys
.
2 Lungs
.
3 Bile and feces
.
4 Skin
.
4. Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage reservoir of the drug.
Storage reservoirs:
1 Assure that the drug will reach its intended target tissue
.
2 Are the reason for giving loading doses
.
3 Increase itheilengthiofitime iaidrugiis iavailable iandiactive
.
4 Are most common in collagen tissues
.
5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s:
1 Propensity to go to the target receptor
.
2 Biological ihalf-life
.
3 Pharmacodynamics
.
4 Safety and side effects
.
6. Azithromycin dosing requires that the first day’s dosage be twice those of the other 4 days of the prescription. This
isconsidered a loading dose. A loading dose:
1 Rapidlyiachieves idrugilevels iinitheitherapeuticirange
.
2 Requires four- to five-half-lives to attain
.
3 Is influenced by renal function
.
4 Is directly related to the drug circulating to the target tissues
.
7. The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the:
1 Minimum adverse effect level
.
2 Peak of action
, .
3 Onset iofiaction
.
4 Therapeutic range
.
8. Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
1 When the drug has a wide therapeutic range
.
2 When the drug will be administered for a short time only
.
3 When there is a high correlation between the dose and saturation of receptor sites
.
4 Toidetermine iifiaidrugiis iinitheitherapeuticirange
.
9. A laboratory result indicates that the peak level for a drug is above the minimum toxic concentration. This means
thatthe:
1 Concentration will produce therapeutic effects
.
2 Concentrationiwill iproduce ianiadverse iresponse
.
3 Time between doses must be shortened
.
4 Duration of action of the drug is too long
.
10. Drugs that are receptor agonists may demonstrate what property?
1 Irreversible binding to the drug receptor site
.
2 Upregulation with chronic use
.
3 Desensitizationior idownregulationiwithicontinuous iuse
.
4 Inverse relationship between drug concentration and drug action
.
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
1 Downregulation of the drug receptor
.
2 An iexaggeratediresponse iifiabruptlyidiscontinued
.
3 Partial blockade of the effects of agonist drugs
.
4 An exaggerated response to competitive drug agonists
.
12. Factors that affect gastric drug absorption include:
1 Liver enzyme activity
.
2 Protein-binding properties of the drug molecule
.
3 Lipidisolubilityiof ithe idrug
.
4 Ability to chew and swallow
.
13. Drugs administered via IV:
1 Need to be lipid soluble in order to be easily absorbed
.
2 Begin idistributioniintoitheibodyiimmediately
.
3 Are easily absorbed if they are nonionized
.
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