NSG 6005 Midterm (Pharmacology) – Questions
And Verified Solutions
Drugs that use CYP3A4 isoenzymes for metabolism may ✔️Ans - Both 1
and 2
Drugs that have a significant first-pass effect ✔️Ans - Are rapidly
metabolized by the liver and may have little if any desired action
a patient's nutritional intake and lab work reflect hypoalbuminemia. This is
critical to prescribing because: ✔️Ans - distribution of drugs to target
tissue may be affected
The route of excretion of a volatile drug will likely be: ✔️Ans - the lungs
the point in time on the drug concentration curve that indicates the first
sign of a therapeutic effect is the ✔️Ans - onset of action
factors that affect gastric drug absorption include ✔️Ans - lipid
solubility of the drug
which one of the following statements about bioavailability is true ✔️Ans
- bioavailability issues are especially important for drugs with narrow
therapeutic ranges or sustained release mechanisms
steady state is ✔️Ans - when the amount of drug in the body remains
constant
the time required for the amount of drug in the body to decrease by 50% is
called ✔️Ans - half-life
An advantage of prescribing a sublingual medication is that the medication
is ✔️Ans - absorbed rapidly
a nurse practitioner would prescribe the liquid form of ibuprofen for a six-
year-old because ✔️Ans - a six-year-old may have problems swallowing
pills
, The first step in the prescribing process according to the world health
organization is ✔️Ans - diagnosing the patient's problem
Patient education regarding prescribed medication includes ✔️Ans -
Discussion of expected
ADRs
Pharmacokinetic factors that affect prescribing include ✔️Ans -
Bioavailability
Infants and young children are at higher risk of ADRs due to: ✔️Ans -
Lack of safety and efficacy studies in the pediatric population
The elderly are at high risk of ADRs due to: ✔️Ans - Age-related
decrease in renal-function
The type of ADR that is the result of an unwanted but otherwise normal
pharmacological
action of a drug given in the usual therapeutic doses is: ✔️Ans - Type A
A patient may develop neutropenia from using topical Silvadene for burns.
Neutropenia
is: ✔️Ans - A cytoxic hypersensitivity reaction
The angiotensin converting enzyme (ACE) inhibitor Lisinopril is a known
teratogen.
Teratogens cause Type ______ ADR. ✔️Ans - D
A twenty-four-year-old male received multiple fractures in a motor vehicle
accident that
required significant amounts of opioid medication to treat his pain. He is at
risk for Type
__________ ADR when he no longer requires the opioids ✔️Ans - E
Which of the following factors may adversely affect a patient's adherence to
a
therapeutic drug regimen? ✔️Ans - Both A and B
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