Pharmacy: 486 Questions and Answers 100% VERIFIED 2023/2024
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Course
PHARMACY
Institution
PHARMACY
What is the appropriate anticoagulant if CHAD score is 5 ?
Answer
Aspirin, clopidogrel, dabigatran 2 or more(OAC)
2
In patient with septic shock what is the most important step?
Answer
A- Take cultures
B-Administer fluid
C-Give empirical antibiotics
3
In child with ADHD what is the approp...
ادعو لي بي النجاح في االختبار ولكل من ساهم في جمع االسئله وحلها ومراجعتها
AnswersPharmacy File number 2
QuestionsVIVA
VOCE- PROMETRIC 1- 1000 EXAM-
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,1 What is the appropriate anticoagulant if CHAD score is 5 ?
Answer Aspirin, clopidogrel, dabigatran
2 or more(OAC)
2 In patient with septic shock what is the most important step?
Answer A- Take cultures
B-Administer fluid
C-Give empirical antibiotics
3 In child with ADHD what is the appropriate choice?
Answer A- guanfacine once daily
B- Methylphenidate once daily
C- Methylphenidate 6-time daily
D- Methylphenidate prn
For preschool children (age 4 through 5 years) who meet the diagnostic criteria for ADHD,
we recommend behavior therapy rather than medication as the initial therapy When
medication is necessary for preschool children, we suggest methylphenidate rather than
amphetamines or non-stimulants
For most school-aged children (≥6 years) and adolescents with ADHD who meet specific
criteria , we suggest treatment with medication rather than behavior therapy alone or no
intervention
4 In Irritable bowel syndrome what is the most causative factor?
Answer Psychosocial stressor
Genetic predisposition
Experts think these problems may play a role in causing IBS. These problems include
Stressful or difficult early life events, such as physical or sexual abuse
Certain mental disorders, such as depression , anxiety , and somatic symptom disorder
Bacterial infections in your digestive tract
Small intestinal bacterial overgrowth, an increase in the number or a change in the type of
bacteria in your small intestine
Food intolerances or sensitivities, in which certain foods cause digestive symptoms
Research suggests that genes may make some people more likely to develop IBS.
5 What is the most common side effect of bisphosphonate
Answer Oral bisphosphonates may cause local irritation of the upper gastrointestinal (GI) mucosa,
resulting in reflux, esophagitis, and/or esophageal ulcers.
Intravenous (IV) bisphosphonates are often associated with an acute-phase reaction within
24 to 72 hours of the infusion, characterized by low-grade fever, myalgias, and arthralgias.
Both oral and IV bisphosphonates can cause transient hypocalcemia, but more frequently
after IV than oral administration.
Rarely, patients have experienced severe musculoskeletal pain (bone, joint, and/or muscle
pain) within days, months, or years after starting a bisphosphonate, and symptoms do not
always resolve completely with discontinuation of therapy
6 Which bisphosphonate is associated with gastric ulcer?
Answer Oral bisphosphonates (Alendronate, Risedronate)
7 Which treatment of osteoporosis could be given monthly?
Answer BISPHOSPHONATE FORMULATION DOSING FREQUENCY
Alendronate Oral tablet Daily or weekly
Ibandronate Oral tablet Daily or monthly
Intravenous Every 3 months
Risedronate Oral tablet Daily or weekly
DOSING INSTRUCTIONS FOR ORAL BISPHOSPHONATES
• Take with 6 to 8 ounces of plain water only
[Note: Take risedronate delayed-release tablet with at least 4 ounces of plain water]
• Take at least 30 minutes (60 minutes for ibandronate) BEFORE other food, drink, or
medications
[Note: Take risedronate delayed-release tablet immediately AFTER breakfast]
•Remain upright and do not lie down or recline for at least 30 minutes (60 minutes for
ibandronate) after taking
8 What is the dose of ferrous sulfate that treat anemia?
Answer 100 TID
500 BID
A 325 mg ferrous sulfate tablet contains 65 mg of elemental iron per tablet; three tablets per
day will provide 195 mg of elemental iron
9 Treatment of hypertension in black patient?
Answer A thiazide-like diuretic or long-acting dihydropyridine calcium channel blocker should be
used as initial monotherapy in black patients
10 Which hormone is associated with fetal productive abnormalities?
Answer Androgen, Estrogen, progesterone
11 8-what is equivalent to omeprazole 20 mg?
Answer A-esomeprazole 40 mg
B-Pantoprazole 40 mg
C-Ranitidine 300 mg daily
12 How to start anti- hypertension in elderly?
Answer A-Start low dose and increase gradually
B-Start normal dose and decrease gradually
C-Not different from adult dose
13 Phase 1 of drug development
Answer A-pharmacokinetics study in human
B-Safety and efficacy in human
In phase1 Goal is to gather information on the pharmacokinetic and pharmacodynamics
properties
14 Progestin can be used in breast feeding women
Answer The weight of an adequate body of evidence and/or expert consensus suggests this drug
poses minimal risk to the infant when used during breastfeeding (Micromedex)
Progesterone is present in breast milk.
The manufacturer recommends that caution be used if progesterone is administered to a
breastfeeding female.(uptodate)
15 Side effect of albuterol
Answer Common:
Tachycardia, Nausea , Pharyngitis , Viral gastroenteritis , Vomiting, Backache
Feeling nervous, Headache, Sinus headache, Tremor, Urinary tract infectious disease
Bronchitis, Cough, Nasopharyngitis, Pain in throat, Rhinitis , Sinusitis, Upper respiratory
infection, Pain.
16 CYP2D6 with codeine when the effect is reduce?
, Answer (Poor metabolizer, rapid metabolizer)
17 Septic shock 1st line?
Answer Norepinephrine IV infusion
18 Status epilepticus treatment
Answer Benzodiazepines are the first-line treatment for convulsive status epilepticus because they
control seizures rapidly
For IV therapy, lorazepam is preferred in adults [6]; midazolam is preferred for
intramuscular (IM), intranasal or buccal therapy; and diazepam is preferred for rectal
administration.
Lorazepam – Use of lorazepam as a first-line agent
20 Oleaginous base for ointment?
Answer (Lanolin, white petroleum, hydrophilic petroleum, PEG)
Oleaginous base: white petroleum
Absorption base: Lanolin, hydrophilic petroleum
O/W: PEG ointment
21 Bromocriptin which medication to prevent nausea should be given
Answer (one of option domperidone, metclopramide)
22 Nitroglycerin MOA
Answer Nitroglycerin, an organic nitrate, is a vasodilating agent that relieves tension on vascular
smooth muscle and dilates peripheral veins and arteries. It increases guanosine 3'5'
monophosphate (cyclic GMP) in smooth muscle and other tissues by stimulating guanylate
cyclase through formation of free radical nitric oxide. This activity results in
dephosphorylation of the light chain of myosin, which improves the contractile state in
smooth muscle results in vasodilation
23 Amantadine MOA
Answer Pharmacologic Category
Anti-Parkinson Agent, Dopamine Agonist; Antiviral Agent; Antiviral Agent, Adamantane
Mechanism of Action
Amantadine and rimantadine interfere with the function of the viral M2 protein, possibly
blocking uncoating of the virus particle and preventing viral release within infected cells.
In Parkinson disease
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