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Biological Molecules (AQA Biology) A* notes

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An in-depth, clearly organised, summary of Biological Molecules (the first topic in AS or A-level Biology for the AQA exam board). These are notes that got me an A* in A-level Biology in the 2023 exam year. Can be used for revision as well as understanding.

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  • November 14, 2023
  • 16
  • 2022/2023
  • Class notes
  • Aqa standard
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biological molecules
carbohydrates
monomers: smaller units from which polymers: molecules made from a
larger molecules are made large number of repeating monomers
joined together

organic compounds which comprise of only C, H and O

carbohydrates are sugars that come in 2 main forms – simple and complex. This
is also referred to as simple sugars and starches.

monosaccharides:
carbohydrate monomers white crystalline solids

simplest "single sugars" same number of C as O atoms

highly soluble. dissolve in water to general formula (CH2 O )n  [n
​ ​




form sweet tasting solutions between 3 and 7]

e.g. glucose, fructose and galactose

hexose monosaccharides

glucose
there is alpha and beta glucose (structural isomers)




biological molecules 1

, the OH position is different, this minor structural difference has a major
effect on biological roles of alpha and beta glucose

carbons are numbered clockwise!

fructose and galactose

the other two hexose monosaccharides to learn

fructose is very soluble- main sugar in fruit/ nectar

galactose is not as soluble as glucose- important in production of
glycolipids and glycoproteins

pentose monosaccharides

pentose monosaccharides have 5 carbon atoms

ribose and deoxyribose (which has one less oxygen- deoxy*) are in RNA and
DNA

all monosaccharides and some disaccharides are reducing sugars- a sugar that
serves as a reducing agent due to its free aldehyde or ketone functional groups in
its molecular structure.



biological molecules 2

, sugars that can donate electrons (or hydrogen) to reduce (reduction is gaining
electrons) another chemical such as Benedict's reagent

disaccharides
condensation reaction: two molecules hydrolysis reaction: breaks a
chemically joining with the removal of chemical bond between two
water molecules and involves the use of a
water molecule

when they join, a glycosidic bond is formed. between the hydroxyl groups of both

the condensation reaction removes the H2 O but an O is then "left behind" as part of





the glycosidic bond!

e.g. C6 H12 O6
​ ​ ​ + C6 H12 O6 → C12 H24−2 O12 
​ ​ ​ ​ ​ ​




a 1-4 glycosidic bond is formed for maltose, sucrose and lactose (the
disaccharides to know)

MONOSACCHARIDE + MONOSACCHARIDE → DISACCHARIDE
glucose glucose maltose

glucose galactose lactose
glucose fructose sucrose

polysaccharides
polymers containing monosaccharides linked with glycosidic bonds

formed by condensation reactions and mostly used as energy store and structural
components

we need to know about starch [plants], cellulose [plants] and glycogen [animals]—
all insoluble!

STARCH

made of many alpha glucose molecules

see iodine test for starch

good storage molecule as:




biological molecules 3

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