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Chapter 13 Antimicrobial Susceptibility testing| 73 questions and answers $13.99   Add to cart

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Chapter 13 Antimicrobial Susceptibility testing| 73 questions and answers

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Antimicrobial Susceptibility testing -To determine which antimicrobial agents might be effective in treating infections -Need to disntinguish pathogens from commensals -Generally disk diffusion or dilution Reasons for Antimicrobial susceptibility -Suspect a isolate is involved in pat...

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  • October 2, 2023
  • 13
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
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Chapter 13: Antimicrobial Susceptibility testing 73 questions and answers
Antimicrobial Susceptibility testing - answer -To determine which antimicrobial agents might be effective in treating infections
-Need to disntinguish pathogens from commensals
-Generally disk diffusion or dilution
Reasons for Antimicrobial susceptibility - answer -Suspect a isolate is involved in patient infection
-Susceptibility against particular antimicrobial is uncertain
Group A strep - answer Susceptible to penicillin
Epidemiological Cut-off valves (ECV) - answer Helps identify emerging resistance
Factors to consider in susceptibility testing - answer - Body site from which the bacterium is isolated
- Presence of other organisms - Specimen quality
- Host status
Body Site - answer - Susceptibility test are not routinely performed on organisms isolated from an anatomic site for which they are normal inhabitants Ex: E. coli is normal in the GI tract and therefore would not be tested when isolated from a stool sample
Specimen Quality - answer - Pure cultures indicate good specimen quality
- Contamination is indicated if more than two species with greater than 10^5 colony forming units (CFU's)
Host status in susceptibility testing - answer - Normal flora may represent infection in immunocompromised patients
- Host may be allergic to drug so different choice is needed
Who makes the decision in selecting antimicrobials for testing and reporting - answer Laboratory scientist
Pharmacists
Physicians Therapeutic committee
Selecting antimicrobials for testing - answer - Plate size constraints
- FDA determines used and dosage
- Can be selected by Pharmacists, physicians, and medical technologists
- Interactions of drugs in pediatric patients (Tetracycline and tooth development)
- Outpatients have orally administered medications
Formulary - answer an official list of drugs approved for use by a hospital or group of physicians

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