UNE CHEM 1005 Midterm Review Questions With Complete Solutions
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Course
CHEM 1005
Institution
University Of New England (UNE
)
Which of the following best describes tertiary structure? correct answer: Interactions between alpha helices and beta sheets to form a domain
Movement of ammonia from an amino acid to an alpha-keto acid involves a family a enzymes best categorized as which of the following? correct answer: Tra...
une 1005 midterm review questions with complete so
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University of New England (UNE
)
CHEM 1005
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UNE 1005 Midterm Review Questions With
Complete Solutions
Which of the following best describes tertiary structure? correct
answer: Interactions between alpha helices and beta sheets to
form a domain
Movement of ammonia from an amino acid to an alpha-keto
acid involves a family a enzymes best categorized as which of
the following? correct answer: Transferases
How do most enzymes reduce the activation energy needed to
move a reaction forward? correct answer: Providing an active
site most complementary the transition state
Domains are common structural elements that retain a particular
function within the protein. Which of the following is an
example of a protein domain? correct answer: An arrangement
of beta-strands connected by alpha-helices
Alpha-helices and beta-sheets are primarily stabilized by which
of the following interactions? correct answer: Hydrogen
bonding
Covalent catalysis is used by many enzymes to cleave peptide
bonds. Which of the following amino acids would not facilitate
this type of catalysys? correct answer: Valine
, An enzyme has a mutation within the substrate binding site that
reduces the binding of the coenzyme needed for covalent
catalysis. Which of the following is likely to result as a
consequence of this mutation? correct answer: The enzyme will
not be able to form the transition state complex
Which of the following is the best description of primary protein
structure? correct answer: A newly synthesized strand of amino
acids
If a mutation is made within the active site of an enzyme
resulting in a decrease in Km, which of the following will be
true with respect to the enzyme kinetics? correct answer: The
enzyme will require a lower substrate concentration to reach 1/2
Vmax
Which of the following best describes an enzyme inhibitor that
increases the Km but does not change the Vmax? correct
answer: A competitive inhibitor
Under low energy conditions, AMP will bind to
phosphofructokinase I and glycogen phosphorylase at site
unique to the active site. This enhances the activity of these
enzymes. This is an example of which of the following types of
enzyme regulation? correct answer: Allosteric activation
An enzyme is participating in a general acid-base catalysis
reaction with an optimal reaction pH of 6.0. If acid is added to
the environment reducing the pH to 3, what is the likely impact
to the rate of reaction? correct answer: The rate of reaction is
likely to decrease as the pH is out of optimal catalytic range
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