with facial abnormalities. Intoxication-blood alcohol levels between 100-200 mg/dL.
Death reported at levels ranging from 400-700 mg/dL. Alcohol withdrawal-within 4-12
hours of cessation of drinking (tremors/vomiting/sweating/elevated blood pressure/may
have delirium or hallucinations (2nd or 3rd day onset following cessation of heavy usage).
Sedative, Hypnotic, or Anxiolytic: induce CNS depression and possibly death. Be
aware that CNS depressants are additive; capable of producing physio and psycho
dependence with cross-tolerance or cross-dependence existing between various CNS
depressants. Generally, produce a depressant effect on the body; respiratory depression;
hypotension; may suppress renal function. See figure 25-2 on pg 467.
Withdrawal (6-8 hours)-tremors/sweating/nausea & vomiting/anxiety/may have
hallucinations. Known drug names on table 25-1 on pg. 466.
, CNS Stimulants: caffeine and nicotine are most common; cocaine (may be in form of
crack) most potent; methamphetamine (crystal meth) seems to be most addictive.
Produces stimulation of CNS…mild alertness with caffeine to intense rush and euphoria
with meth. Withdrawal develops with hours to days…. crashing. Serious risk of heart
attack with usage of cocaine.
Inhalant Abuse and Dependence: paints, solvents, aromatic hydrocarbons. “huffing”
…mild withdrawal…. seen mostly in adolescent population. Generally, act as CNS
depressant. Mild withdrawal.
Opioid Abuse and Dependence: refers to opium and opium derivatives. Desensitize
both psychological and physiological pain…. seldom able to hold a steady job.
Constantly seeking next dose. CNS manifestations include euphoria, mood changes and
mental clouding/impaired judgment; drowsiness and pain reduction; pupillary
constriction. May have initial nausea/vomiting until “use” to it. Symptoms occur 6-12
hours after last dose with peak 1-3 days after last dose and gradually subside over 5-7
days.
Hallucinogen Abuse and Dependence: distort an individual’s perception or reality.
“Mind expanding” by users. Common danger is a “flashback” or a spontaneous
reoccurrence of the hallucinogenic state without ingestion of the drug.
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