NU 150 Pharmacology Test 3 (Galen
College) Questions and Answers 2023
NSAIDs (actions) - CORRECT ANSWER-Actions: Does not belong to steroid group
of drugs Inhibit prostaglandin synthesis by inhibiting an enzyme that triggers pain
and inflammation.
NSAIDs (Therapeutic class) - CORRECT ANSWER-Anti-inflammatory, Antipyretic,
Analgesic
NSAIDs (examples) - CORRECT ANSWER-ibuprofen (Motrin, Advil) indomethacin
(Indocin) ketorolac (Toradol) naproxen (Naprosyn) piroxicam (Feldene) celecoxib
(Celebrex)
NSAIDs (uses) - CORRECT ANSWER-Mild to moderate pain Rheumatoid Arthritis
Osteoarthritis Dysmenorrhea
Morphine (uses) - CORRECT ANSWER-Prototype or "model" opioid
Effective for moderately severe to severe pain Relief of severe cough (codeine)
Pulmonary Edema (morphine) Obstetric Analgesia (nubain) Pre-operative to lessen
anxiety and sedate
Morphone (actions) - CORRECT ANSWER-Actions on organs:
CNS: drowsiness, euphoria, sedation, mental clouding
Eye: pupil constriction (pinpoint pupil) (miosis)
Resp: depressed rate/depth of respirations and aggravation of asthma: suppress
cough reflex (codeine)
GIT = ↓peristalsis in stomach & intestines; gastric, ↓pancreas/bile secretions;
gallbladder spasm (morphine) GUT = bladder contraction/spasm (urinary retention)
Skin: itching and rash
Morphone (adverse reactions) - CORRECT ANSWER-Adverse reactions:
Physical dependence
Possible withdrawal symptoms upon discontinuing.
Opioid tolerance
Need to address the patient's pain because it takes priority over concerns about drug
addiction or physical dependence.
Symptoms of opioid withdrawal - CORRECT ANSWER-Early signs
Yawning, perspiring, tearing, nasal drainage
Followed by:
Gooseflesh (goosebumps) • Abdominal cramps • Bone and muscle pain (rebound
pain) • N/V, diarrhea • Mydriasis (pupil dilation) • Intense craving for drug • Agitation •
Elevated BP, tachycardia • Seizures
Morphone (precautions) - CORRECT ANSWER-Use cautiously in individuals with
head injury, morbid obesity, and sleep apnea.
, Precautions: Elderly: extreme confusion and hallucinations; smaller doses than
younger adult Undiagnosed abdominal pain Liver disease
Home use: Drug may cause drowsiness, dizziness • Caution with driving • Avoid
alcohol • Take med as directed • Explain how-to put-on patch
Patient education on PCA machine: - CORRECT ANSWER-Location of buttons •
Regulation of dose and time interval • Assure machine will not deliver dose until
correct time • Pain relief should occur shortly after pushing button • Inform nurse if
pain not relieved after two doses
Naloxone (Narcan) (Use) - CORRECT ANSWER-Complete or partial reverse of
opioid effects after surgery or overdose
Naloxone (Narcan) (adverse reaction) - CORRECT ANSWER-n/v, tachycardia,
hypertension, return of postoperative pain, fever and dizziness
Hydrocodone (use) - CORRECT ANSWER-severe pain
Hydrocodone (adverse reaction) - CORRECT ANSWER-Sedation, sweating,
headache, vertigo, lethargy, confusion, lightheadedness, nausea, vomiting
Meperidine (Demerol) opioid (use) - CORRECT ANSWER-Acute moderate to severe
pain, preoperative sedation, anesthetic adjunct
Meperidine (Demerol) opioid (adverse reaction) - CORRECT ANSWER-
Lightheadedness, constipation, dizziness, N/V, respiratory depression
Anticholinergic (glycopyrrolate) cholinergic blocking drug (uses) - CORRECT
ANSWER-Parasympathetic drug (rest and digestion)
Oral: peptic ulcer
Parenteral: in conjunction with anesthesia to reduce bronchial and oral secretions, to
block cardiac vagal
DRY "Can't see, pee, sh*t, spit" Hot as a Hare Dry as a Bone Blind as a Bat Red as
a Beet Mad as a Hatter
CV: increase heart rate Resp: dry mucus membranes; bronchial dilation
GIT: decrease GI motility, secretions and salivation
GUT-decrease bladder contraction, urinary retention
Eye: pupil dilation, increase in intraocular pressure
Anticholinergic (glycopyrrolate) cholinergic blocking drug (indications) - CORRECT
ANSWER-Indications:
↓ muscle rigidity and diminishes tremors (Parkinson's)
inhibit the vagal stimulus (increase HR in bradycardia)
Bronchospasm (dilate bronchioles in asthma)
irritable bowel syndrome (relief of diarrhea S/S)
Urinary incontinence (relief of urgency in urination)
↓gastric & pancreatic secretions (acute pancreatitis)
↓ reduce respiratory secretions (pre-op)