MLS Hematology 2023 Final Exam | Questions & Answers (Graded A+)
MLS Hematology 2023 Final Exam | Questions & Answers (Graded A+)
Which is true regarding the red blood cell? - ANSWER - The body increases the amount of RBC progenitors at all times to increase the response time when anemia occurs...
MLS Hematology 2023 Final Exam |
Questions & Answers (Graded A+)
Which is true regarding the red blood cell? - ANSWER - The body increases the amount of RBC progenitors at all times to increase the response time when anemia occurs.
Active hematopoiesis in an adult would most likely take place in the: - ANSWER - Hip
What are the two reasons that the erythrocyte loses its nucleus?(multiple) - ANSWER - To gain membrane deformability; To allow for better oxygen transport into the tissues
What is the major function of the erythrocyte? - ANSWER - Oxygen transport
Which descibe intravascular hemolysis?(multiple) - ANSWER - It can result from membrane damage caused by the turbulence in the chambers of the heart; It can be triggered by membrane-bound complement proteins
Why do newborns have a higher normal red cell count than adults? - ANSWER - The
newborns cells have a higher concentration of Hgb F which has a higher affinity for oxygen
As the erythrocyte matures, why does it decrease in size? - ANSWER - It undergoes multiple cell divisions
Which term describes hematopoiesis that takes place outside the bone marrow? - ANSWER - Extramedullary
Match the organ: Liver - ANSWER - Can be site of hematopoiesis during bone marrow failure
Match the organ: Kidney - ANSWER - involved in the detection of hypoxia in erythrocytes
Match the organ: Thymus - ANSWER - the site for T cell maturation
Match the organ: Spleen - ANSWER - Involved in the removal of damaged or senescent red blood cells
Match the organ: Lymph nodes - ANSWER - Site of antigenic encounter for specific B cells and T cells
Match the organ: Bone Marrow - ANSWER - The major site for hematopoiesis in an adult A cardiac patient would be expected to have a lower number of red cells in circulation due to his physiological condition. - ANSWER - False
As the erythrocyte matures, why does the cytoplasm change from blue to pink? (multiple) - ANSWER - Blue-staining RNA synthesis decreases; Pink-staining hemoglobin synthesis increases
The number of RBCs in circulation is controlled by a variety of factors. Which would NOT be considered a normal control mechanism? - ANSWER - Necrosis
Which defines the last mitotic stage of erythropoiesis? - ANSWER - Polychromatic normoblast
A stem cell committed to becoming a B cell will have which CD marker? - ANSWER -
CD19
Which best defines a stem cell? (multiple) - ANSWER - Is subject to apoptosis if the numbers are too high; can give rise to an identical daughter cell without differentiation; has the ability to differentiate into all functional cell types
Match the cell type: Endothelial cells - ANSWER - Help regulate the passage of particles entering and leaving the hematopoietic spaces
Match the cell type: Macrophages: - ANSWER - Store recycled iron
Match the cell type: Stromal cells - ANSWER - Originate from the mesenchymal cells
Match the cell type: Mesenchymal cells - ANSWER - A type of embryonic tissue that migrates into the marrow to support blood cell development
Match the cell type: Adipocytes - ANSWER - Help regulate the volume of the bone marrow
Match the cell type: Reticular adventitial cells - ANSWER - Extend fibers into the bone marrow cavity on which mature blood cells will adhere
Erythropoietin has a positive influence on erythropoiesis. Which would be considered
a mechanism of action by the hormone? (multiple) - ANSWER - It inhibits the production of adhesion molecule receptors on the maturing red blood cell; It stimulates RNA synthesis of the red blood cells; It inhibits normal apoptosis; It causes an increase in the release of reticulocytes form the bone marrow
What ultimately happens to the nucleus of the mature erythrocyte? - ANSWER - It is extruded from the cell in a membrane-bound vesicle and is phagocytized by macrophages
During hematopoiesis, which cell type, located toward the middle of the extravascular cord in the bone marrow, undergoes receptor-mediated migration toward the periphery of the cord as they mature? - ANSWER - Granulocytes
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