Exam (elaborations)
NR 565 - advanced pharmacology midterm - Chamberlain 2023/2024
- Institution
- Chamberlain College Of Nursing
NR 565 - advanced pharmacology midterm - Chamberlain
[Show more]
Content preview
NR 565 - advanced pharmacologymidterm - Chamberlain
During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? - ~ANSWER 1st trimester (fetus most at risk d/t rapid growth)
What is BEERS criteria? - ~ANSWER Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides
What is the CYP450 (cytochrome P450) - ~ANSWER liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interactions CYP450 inducers - ~ANSWER Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect (decrease blood levels of drug), elevate CYP450 enzymes
CYP450 inducers pneumonic - ~ANSWER "Bullshit Crap GPS INDUCES rage"
CYP450 inducer drug names - ~ANSWER Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas
CYP450 inhibitors - ~ANSWER inhibit metabolism, increase blood levels of medications
CYP450 pneumonic - ~ANSWER "VISA credit card debt INHIBITS spending on designers like CK to look GQ" CYP450 inhibitors drug names - ~ANSWER Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine
Physiological changes during pregnancy that impact pharmacodynamics and pharmacokinetic properties of drugs? - ~ANSWER increase glomerular filtration rate leads to increase durg excretion increase hepatic metabolism
decrease tone and motility of bowel
increase drug absorption
Examples of medications that can be teratogenic - ~ANSWER Antiepileptic drugs, antimicrobials such as tetracyclines and fluoroquinolones, vitamin A in large doses, some anticoagulants, and hormonal medications such as diethylstilbestrol (DES).
How is absorption of intramuscular medications different in neonates? - ~ANSWER slow and erratic due to low blood flow in muscles first few days of life Why is absorption of medication in the stomach increased in infancy? - ~ANSWER delayed gastric emptying
Some medications that should be avoided in the pediatric patient? - ~ANSWER glucocorticoids, discoloration of developing teeth with tetracyclines, and kernicterus with sulfonamides, levofloxacin (antibiotics) aspirin (Severe intoxication from acute overdose)
what should be included in medication administration patient education? - ~ANSWER dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic
What are some things that put the elderly patient at higher risk for adverse drug reactions? - ~ANSWER reduced renal function polypharmacy (the use of five or more medications daily)
greater severity of illness
presence of comorbidities
use of drugs that have a low therapeutic index (e.g., digoxin)
increased individual variation secondary to altered pharmacokinetics
inadequate supervision of long-term therapy
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller PERFECTGRADES. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
80364 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now