Name 5 anatomical areas critical in schizophrenia
Nucleus accumbens, Ventral tegmental area (VTA), Hippocampus, Striatum and
Subtantia Nigra (SN).
NA, VTA, HIPPO, STRIA, SN
Typical antipsychotic cause movement abnormalities
Which type of abnormalities appear in hours to days?
Acute dystonic ...
NURS 660 SUM 2019 Exam 1 Stahl's Ch 5 - schizophrenia: pathways, sympts, anatomy . CORRECT ANSWERS DIAGRAM ELA BORATION INCLUSIVE 2023//2024 Name 5 anatomical areas critical in schizophrenia Nucleus accumbens, Ventral tegmental area (VTA), Hippocampus, Striatum and Subtantia Nigra (SN). NA, VTA, HIPPO, STRIA, SN Typical antipsychotic cause movement abnormalities Which type of abnormalities appear in hours to days? Acute dystonic rxn - sustained muscle contraction; treat with IM benadryl or benztropine Explain the role of NMDA in the negative and cogntive symptoms of schizophrenia hypoactive NMDA receptors -> cortico -brainstem overactive -> excess glutamate at VTA -
> excess stimulation of brainstem pyramidal neurons -> INHIBITION of mesocortical DA neurons DECREASE NMDA -> EXCESS GLUTAMATE -> INHIBIT DOPAMINE NEURONS What movement disorders appear in days to weeks after starting antipsychotic ? Akathisia - restless, feeling the need to move; getting up and walking frequently Review image of the brain areas and affects in schizophrenia The mesolimbic dopamine pathways travels from ________________ to ____________. Ventrotegmental area (VTA) of brainstem to the neucleus accumbens in the ventral stratum --(VTA ->NA) What ar the 3 main areas of the brain Cerebrum, cerebellum and brainstem What ar the 4 areas of the cerebellum Thalamus, hypothalamus, amygdala and hippocampus
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