Nurs 615 Pharm Exam 1 – Maryville Latest 2023 (100%
Correct Answers)
How does hypoalbuminemia affect the process of prescribing? - correct answer
✅Low albumin = more free drug (bc the drug can't bind to albumin aka protein) =
increased adverse effects
What is a Black Box Warning: - correct answer ✅is considered a contraindication
to administer that drug.
What is the drugs half-life? - correct answer ✅Half-life specifically means the
amount of time it takes for an administered drug to be halfway cleared from the
system.
Peak of action: - correct answer ✅the time between drug administration and
maximum concentration of drug in the blood stream. Best therapeutic effect.
Duration of action: - correct answer ✅the time between onset of action and
metabolism of drug below the minimum needed for an effect. The length of time
you have the drug in your system.
According to the WHO what is the first step in the prescribing process? - correct
answer ✅The first step is to define the patient's problem
,Nurs 615 Pharm Exam 1 – Maryville Latest 2023 (100%
Correct Answers)
The second step is to - correct answer ✅specify the therapeutic objective
The third step is to - correct answer ✅choose which drug or treatment is needed.
Step 4 of the WHO approach: - correct answer ✅Start the treatment
Step 5 of the WHO approach: - correct answer ✅Educate the patient
Step 6 of the WHO approach: - correct answer ✅Monitor the treatment
Phase 1 of drug development: - correct answer ✅The drug is tested on healthy
volunteers
Phase 2 of drug development: - correct answer ✅trials with people who have the
disease for which the drug is thought to be effective
Phase 3 of drug development: - correct answer ✅Large numbers of patients in
medical research centers receive the drug in phase 3. This larger sampling
provides information about infrequent or rare adverse effects. The FFA will
approve a new drug application if phase 3 studies are satisfactory.
Phase 4 of drug development: - correct answer ✅This phase is voluntary and
involves postmarket surveillance of the drug's therapeutic effects at the
completion of phase 3. The pharmaceutical company receives reports from
doctors and other health care professionals about the therapeutic results and
adverse effects of the drug. Some medications, for example, have been found to
be toxic and have been removed from the market after their initial release.
Explain first pass metabolism - correct answer ✅much of the drug is lost in the
absorption process. The liver metabolizes many drugs, thus reduces the
bioavailabilty of the drug.
What is the fasted route of absorption: - correct answer ✅The fastest route of
absorption is inhalation, and not as mistakenly considered the IV administration.
Why does the GI tract take longer to absorb? - correct answer ✅The GI tract is
lined with epithelial cells; drugs must permeate through these cells in order to be
absorbed into the circulatory system.
What is One particular cellular barrier that may prevent absorption of a given
drug? - correct answer ✅the cell membrane. Cell membranes are essentially lipid
bilayers which form a semipermeable membrane. Pure lipid bilayers are generally
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