USMLE Step 1 Rapid Review With Complete Solution
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without JVD)
Budd-Chiari syndrome
Achilles tendon xanthoma
Familial hypercholesterolemia
Adrenal hemorrhage, hypotension, DIC
Waterhouse-Friderichsen syndrome (meningococcemia)
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints
Marfan's (fibrillin defect)
Athlete with polycythemia
Erythropoietin injection
Back pain, fever, night sweats, weight loss
Pott's (TB to the vertebrae)
Bilateral hilar adenopathy, uveitis
Sarcoid
Blue sclera
Osteogenesis imperfecta
Bluish line on gingiva
Burton's line - lead poisoning
Bone pain, bone enlargement, arthritis, (also increased hat size, fracture, increased alk
phos)
Paget's
Bounding pulses, diastolic hear murmur, head bobbing
Aortic regurg
Café-au-lait spots, Lisch nodules
NF (1 = optic glimoas and pheo, 2 = acoustic Schwannomas)
Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty
McCune-Albright syndome (G protein problem)
Calf pseudohypertrophy
Duchenne's muscular dystrophy
Cherry-red spot on macula
Tay-Sachs, Niemann-Pick, central retinal artery occlusion
Chest pain, pericardial effusion/friction rub, persistent fever following MI
Dressler's (autoimmune post-MI)
Child uses arms to stand up from squat
Gower's sign (Duchenne's)
Child with fever develops red rash on face that spreads to body
Slapped cheek - B19
Chorea, dementia, caudate degeneration
Huntington's
Chronic exercise intolerance with myalgia, fatigue, painful cramps
McArdle's (muscle phosphorylase deficiency)
Cold intolerance
Hypothyroidism
Conjugate lateral gaze palsy, horizontal diplopia
, Internuclear ophthalmoplegia (MS or stroke)
Continuous machinery heart murmur
PDA
Cutaneous/dermal edema due to CT expansion
Myxedema
Dark purple skin / mouth nodules
Kaposi's sarcoma
Deep, labored breathing / hyperventilation
Kussmaul breathing, DKA
Dermatitis, dementia, diarrhea
Pellagra (B3 / niacin deficiency)
Dilated cardiomyopathy, edema, polyneuropathy
Wet beriberi (B1 / thiamine deficiency)
Dog or cat bite resulting in infection
Pasteurella multocida (local cellulitis)
Dry eyes, dry mouth, arthritis
Sjogren's syndrome
Dysphagia (esophageal webs), glossitis (smooth tongue), iron deficiency anemia
Plummer-Vinson syndrome
Elastic skin, hypermobility of joints
Ehler-Danlos (type III collagen)
Enlarged. hard left supraclavicular node
VIrchow's node (abdominal met)
Erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells
Sezary syndrome (cutaneous T cell lymphoma)
Facial muscle spasm upon tapping
Chvostek's sign (hypocalcemia)
Fat, female, fertile, forty
Gallstones
Fever, chills, headache, myalgia following antibiotic treatment for syphillis
Jarisch-Herxheimer reaction (lysis of spirochetes results in toxin release)
Fever, cough, conjunctivitis, coryza, diffuse rash, Koplick spots
Measles
Fever, night sweats, weight loss
B symptoms or TB
Fibrous plaques in soft tissue of penis
Peyronie's disease
Gout, MR, self-mutilating behavior in a boy
Lesch-Nyhan syndrome (HGPRT deficiency, X-linked recessive)
Green-yellow rings around peripheral iris
Kayser-Fleischer rings (copper accumulation from Wilson's disease)
Hamartomatous GI polyps, hyperpigmentation of mouth, feet and hands
Peutz-Jeghers syndrome
Hepatosplenomegaly, osteoporosis, neurologic symptoms, crinkled cytoplasm
Gaucher's disease (glucocerebrosidase deficiency)
Hereditary nephritis, sensorineural hearing loss, cataracts
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