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Typhoid Fever

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Typhoid fever and paratyphoid fever are similar diseases caused by bacteria. Salmonella Typhi bacteria cause typhoid fever. Salmonella Paratyphi bacteria cause paratyphoid fever. People infected with these bacteria can spread them to others. This typically happens when an infected person uses th...

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  • February 20, 2023
  • 14
  • 2021/2022
  • Presentation
  • Unknown
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Laboratory
investigati
on of
Typhoid
Fever

, 1)Culture
A) Blood culture
• Results of blood cultures are positive in 40-60% of the patients seen early in the course of the
disease
• However, the sensitivity of blood cultures in diagnosing typhoid fever in many parts of the
developing world is limited because widespread liberal antibiotic use may render bacteriologic
confirmation difficult.


B) Stool & urine culture
• Stool and urine culture results become positive after the 1st week
• The stool culture result is also occasionally positive during the incubation period.


C) Bone marrow culture
• Although bone marrow cultures may increase the likelihood of bacteriologic confirmation of
typhoid, collection of the specimens is difficult and relatively invasive.

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