NSG 5003 WEEK 2 QUIZ / NSG5003 WEEK 2 QUIZ: ADVANCED PATHOPHYSIOLOGY-Hypersensitivity is best defined as a(an) - c.
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called: - Anaphylaxis
The common hay fever ...
NSG5003 WEEK 2 QUIZ: ADVANCED PATHOPHYSIOLOGY
Hypersensitivity is best defined as a(an) - c.
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called: - Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins? - IgE
Which type of antibody is involved in type I hypersensitivity reaction? - IgE
Blood transfusion reactions are an example of: - Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated? - c.
Eosinophils
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a
result of which receptor action? - Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed
to develop allergies? - c.
Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions? - d.
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the
erythrocytes are destroyed by - a.
Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the blood
cells are destroyed by: - Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation, tissue damage is a
result of: - d.
Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity reaction? - d.
Natural killer cells
,Graves disease (hyperthyroidism) is an example of which type II hypersensitivity
reaction? - Modulation
Type III hypersensitivity reactions are a result of which of the following? - b.
Antibodies binding to soluble antigens that were released into body fluids and the
immune complexes being deposited in the tissues
A type IV hypersensitivity reaction causes which result? - .
Lymphokine-producing Th1 cells directly attacking and destroying cellular targets
In a type III hypersensitivity reaction, the harmful effects after the immune complexes
that are deposited in tissues are a result of: - Complement activation
Raynaud phenomenon is classified as a type III hypersensitivity reaction and is due to:
- a.
Immune complexes that are deposited in capillary beds, blocking circulation
Deficiencies in which element can produce depression of both B- and T-cell function?
- Zinc
When the maternal immune system becomes sensitized against antigens expressed by
the fetus, what reaction occurs? - Alloimmunity
Tissue damage caused by the deposition of circulating immune complexes containing
an antibody against the host DNA is the cause of which disease? - Systemic lupus
erythematosus
Why does tissue damage occurs in acute rejection after organ transplantation? - a.
Th1 cells release cytokines that activate infiltrating macrophages, and cytotoxic T cells
directly attack the endothelial cells of the transplanted tissue.
Which blood cell carries the carbohydrate antigens for blood type? - Erythrocytes
A person with type O blood is likely to have high titers of which anti-antibodies? - A
and B
Which class of immunoglobulins forms isohemagglutinins? - IgM
Which component of the immune system is deficient in individuals with infections
caused by viruses, fungi, or yeast? - T cells
, In which primary immune deficiency is there a partial-to-complete absence of T-cell
immunity? - DiGeorge syndrome
How many months does it take for the newborn to be sufficiently protected by
antibodies produced by its own B cells? - 6 to 8
Considering the effects of nutritional deficiencies on the immune system, severe
deficits in calories and protein lead to deficiencies in the formation of which immune
cells? - T cells
Urticaria are a manifestation of a which type of hypersensitivity reaction? - Type I
Graves disease is a result of: - c.
Autoantibodies binding to thyroid-stimulating hormone (TSH)-receptor sites
Raynaud phenomenon is an example of which type of hypersensitivity? - Type III
Which statement is true concerning an atopic individual? - They tend to produce more
Fc receptors.
Which statement is true regarding immunodeficiency? - a.
Immunodeficiency is generally not present in other family members
A person with type O blood is considered to be the universal blood donor because type
O blood contains which of the following? - No antigens
Immunoglobulin E (IgE) is associated with which type of hypersensitivity reaction? -
Type I
Graves disease is an autoimmune disease that results in which maternal antibody? - b.
Affecting the receptor for TSH, causing neonatal hyperthyroidism
When a tuberculin skin test is positive, the hard center and erythema surrounding the
induration are a result of which of the following? (Select all that apply.) - T
lymphocytes and Macrophages
Exposure to which of the following could result in a type IV hypersensitivity reaction?
(Select all that apply.) - Poison Ivy, Neomycin, Nickel, Detergents
Which disorders are considered autoimmune? (Select all that apply - Crohns,
Addisons, Rheumatoid arthritis, systemic lupus erythematosus
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller ProfMiaKennedy. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $10.04. You're not tied to anything after your purchase.
