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NAPLEX ACTUAL 2023 EXAM Questions Test Bank {2023 Update} With Questions and Answers
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NAPLEX ACTUAL 2023 EXAM Questions Test Bank {2023 Update} With Questions and Answers
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NAPLEX ACTUAL 2023 EXAM Questions Test Bank {2023 Update } With Questions and Answers T or F. Beyond use date must be applied to each compounded product using USP 795 guidelines for Nonaqueous Liquids and Solid formulation and for Water -containing Formulations. - correct answer True Which of the following is considered with Non -Sterile Pr eparation? A. USP 795 B. USP 797 - correct answer A Labels on Pharmacy -compounded products - Expiration Dates (Beyond Use Dates) - correct answer * Water containing oral formulations * > The beyond use date is no later than 14 days when stored at contro lled cold temperature * Water containing topical/dermal/mucosal liquid and semisolid formulations * > The beyond use date is no later than 30 days * Nonaqueous formulations* > The beyond use date is no later than the time remaining until the earliest exp iration date of any API (use no later than 25% of time of this api) or 6 months, whichever is earlier T or F. For capsules, the label must include mcg or mg/capsule? - correct answer True - Does not require for tablet T or F. You can rinse compounding e quipment with tap water? - correct answer False - you can only rinse Purified water for rinsing equipment What is the best certified sterile compounding environment for injectable product? Which ISO? - correct answer ISO class 5 (class 100) laminar air flow hood within ISO class 7 (class 10,000) clean room * with positive air pressure * differential relative to adjacent areas. ISO class 5 (class 100) clean room with positive air pressure differential relative to adjacent areas or a barrier isolator that provides a ISO class 5 (class 100) environment for compounding T or F. Liquids in a container curve up, therefore measure at the top of the meniscus. - correct answer False. Must measure at the bottom of meniscus What is the difference between glass an d Wedge -wood/Porcelain(ceramic) Mortar and Pestle? - correct answer wedge -wood or porcelain is used commonly and is best for reducing particle size of dry powders and crystals Glass is used for liquids or chemical that are oily or that will stain to the porcelain T or F. It is safe not to use ointment paper to prepare creams and lotions because these two formulation have the highest content of water. Water content will cause the paper to moisten, and possibly tear. - correct answer True. we can use Glas sine weighing paper Which of the following levigating agents are the best to prepare aqueous systems (O/W dispersions)? A. Glycerin B. Mineral oil C. Castor oil D. Cottonseed oil E. Tween 80 - correct answer A. Glycerin > Rest are good levigating agents used to prepare oleaginous systems (W/O) > Additional agents used as levigating agents to prepare aqueous systems consist of Propylene glycol, polyethylene glycol 80 Sometimes heat is used to mix things easier, but it lead to over -heating which produce undesired chemical -reactions. What is the best way to prevent over -heating? - correct answer A water bath will help prevent over -heating Fill in the blank ........................ refer to a compound prepared without a spec ific formula (not from an official compendium) and made specifically to fill the needs of an individual patient - correct answer Extemporaneous Fill in the blank ...................... a single agent that is used to soften and smooth the skin. A moisturi zer is sometimes referred to as ................, but the term ............ is used for single agent, and moisturizers often have coloring, scents, and other ingredients added - correct answer Emollients Fill in the blank Oil in water , or water in Oil i s example of ....... - correct answer Emulsions Fill in the blank ............ Is used to stabilize the emulsion. ........... are usually surfactants (wetting agents) that reduce the surface tension between the two liquids so that the two different subst ances can move close to each other but they will not be mixed together - correct answer Emulsifiers What is the difference between Continental or dry gum method and English, or wet gum method? - correct answer Both have same ingredients (oil, purified w ater and gum (such as acacia) in the ratio of 4:2:1 but the order of mixing is different. Dry method: gum is mixed rapidly with oil then water added all at once Wet method: gum is dissolved in water first, then oil is slowly added What you know about HLB (hydrophilic -Lipophilic balance) number? - correct answer #s range from 0 -20 with 10 being the mid -point means it is the break point between water and oil solubility. #>10 means hydrophilic (water -soluble) and #<10 means lipophilic (lipid -soluble) What i s Eutectic Mixture? - correct answer A eutectic mixture is two or more components that melt at a temperature lower than the melting temperature for the individual components. Which of the following are common preservatives? A. Benzalkonium chloride (BAK ) B. Benzyl alcohol C. Chlorhexidine D. Thimerosal (contain mercury) E. Sodium benzoate F. Benzethonium chloride G. propylparaben - correct answer All of them Why preservative -free formulations if there is no harm from multi -dose vials? - correct answer no scientifically conclusive evidence exists of harm from exposure to thimerosal preservative -containing vaccine, whereas evidence is accumulating of lack of an y harm resulting from exposure to such vaccines. Therefore, the benefits of influenza vaccination outweigh the theoretical risk, if any, for thimerosal exposure through vaccination" (MMWR 54 [RR08]: 1 -40, 2005). Nonetheless, FDA is in discussions with manu facturers of influenza vaccine encouraging them to further increase the supply of preservative -free formulations. Is it safe for pregnant women to receive an influenza vaccine that contains thimerosal? - correct answer Yes. A study of influenza vaccinati on examining over 2,000 pregnant women demonstrated no adverse fetal effects associated with influenza vaccine. Case reports and limited studies indicate that pregnancy can increase the risk for serious medical complications of influenza. One study found t hat out of every 10,000 women in their third trimester of pregnancy during an average flu season, 25 will be hospitalized for flu related complications. Which of the following promote a better medication absorption? A. Lotions B. Creams C. Ointments D. Pa stes - correct answer C. Ointments They are not applied easily to hairy skin Which of the following has higher potency? A. Elocon (mometasone) ointment B. Elocon (mometasone) cream - correct answer A. Elocon ointment is high potency and B is low -medium potency and reason behind this is ointment is 80% oil Which of the followings is 80% oil and 20% water? A. Cream B. Lotion C. Ointment D. Paste - correct answer C. Ointment Cream is 50% oil and 50% water Lotion is mostly water Paste are the thickest ointments and are also used as protective barriers Ex. Triple paste medicated diaper rash ointment List the 5 classes or types of ointment bases? - correct answer Oleaginous bases such as white petrolatum Absorption bases (such as lanolin, Aquaphor) W/O emulsion bases O/W emulsion bases (hydrophilic ointment, Dermabase) Water soluble or water miscible bases (PEG ointment) GELs - correct answer Gels are oil in water with alcohol base Example: Benzoyl peroxide and erythromycin topical acne gel (benzamycin) Also used as Thickeners > example of thickeners are alginates (including Na, K, Ca alginate), agar, carrageenan, gelatin, carbomer, tergacanth, bentonite) List some commonly used bas es in suppositories preparations? - correct answer cocoa butter (theobroma oil) Glycerin Hydrogenated vegetable oils Polyethylene glycol (Carbowax) What is the difference between Syrups and Elixirs? - correct answer Syrups (sugar base) Elixirs (Alcohol base) List 2 plasticizers used to soften the capsule? - correct answer Glycerol and Sorbitol If patient can't take capsule due to Gelatin, what is the other type of capsule that could be dispensed to these customers and it is not made from animal? - correct answer Hypromellose T or F. The larger the size of capsule, the higher the number. - correct answer False. The smaller the size, the higher the number and the smallest capsule size is 5 What is the difference between Pharmacokinetics and Pharmacod ynamics? - correct answer Pharmacokinetics is what the human body does to the drug and pharmacodynamics is what the drug does to the human body What is the difference between Intravascular administration and Extravascular administration? - correct answer Intravascular administration is where the drug is placed directly into the blood either intravenously or intraarterially. Extravascular
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