Cystic fibrosis (CF) is a chronic genetic disease that affects more than 30,000 children
and adults in the United States, and approximately 70,000 people worldwide. This disease
affects people of every racial and ethnic group. In people with CF, mutations in the cystic
fibrosis transmembrane conductance regulator (CFTR) gene cause the CFTR protein to become
dysfunctional. When the protein is not working correctly, it is unable to help move chloride, a
component of salt, to the cell surface. Without the chloride to attract water to the cell surface, the
mucus in various organs becomes thick and sticky. This causes repeated lung infections and
gradually reduces breathing ability in affected patients. Cystic fibrosis is a chronic, lifelong
disease that requires treatment that changes with the patient's needs as they age. CF patients
frequently have recurring symptoms that impact their physical, social, and emotional health.
This disease affects the lungs, pancreas, upper airways, liver, intestine, and reproductive organs,
according to Naehrig et al. (2017). Obstruction, inflammation, infection (in the lungs and upper
airways), tissue reorganization, and loss of function are the outcomes. Other disease-modifying
genes affect the severity of CF. Early diagnosis and treatment improve quality of life for cystic
fibrosis patients. Modern medicine has extended the lives of CF patients. But much of the self-
directed care that improves health and quality of life must be done at home. Unfortunately, non-
adherence to treatment is the leading cause of treatment failure and death in cystic fibrosis
patients.
Cystic fibrosis is a disease that is difficult to manage due to its complexity. Individuals'
symptoms and severity can vary significantly. Numerous factors have an effect on an
individual's health and disease progression. If the screening test is positive, the patient should be
evaluated by a multidisciplinary team composed of physicians, physiotherapists, dieticians,
psychologists,
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller maggieobita. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $17.99. You're not tied to anything after your purchase.
