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Amnesias

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Summary notes on Amnesias for neuropsychology

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  • October 10, 2022
  • 12
  • 2021/2022
  • Class notes
  • Lee ann pileggi
  • All classes
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Amnesias

Lecture 1

Memory

-one of the classic systems of neuropsychology

-when memory fails it fails spectacularly

-memory is fragile-very easy to disrupt as it disrupts all over the brain, e.g. lack of oxygen to
the brain, lack of sleep, stress

-Memory is widespread

-use our memories in almost all aspects of our lives

 Dynamic and malleable meaning it forms the basis of our experiences, how you
remember what is important, memory allows us to construct ourselves-yes that was
me I did that
 Goes forward and backward in time, e.g., goal setting-prospective memory
-Also retrospective-think of the past
 Only noticeable when it’s not working properly
 Disorders in which memory can be affected
 Dementias (e.g., Alzheimer’s disease)
 Toxic conditions (exposed to neurotoxins, can affect hippocampus)
 Anoxia or hypoxia
 Head injury/TBI
 Multiple memory systems
 Processes of encoding, storage, and retrieval
 But memory is not like a hard drive!-pick up all the pieces and pack it together into
the form that it was-won’t be the same as it was before, it is good enough
 Process of retrieval-remember things well enough, this is what happened, not perfect,
memory is more like a chocolate chip cookie-encoding, storage and retrieval
Taxonomy of memory




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, What is memory?

 Understand normal memory processing by studying memory disorders of memory
(i.e., the amnesias), which brain regions are involved
 Anterograde amnesia
 Loss of the ability to encode and learn information after a defined event
 Defined event e.g. Car accident, surgically placed lesion, onset of disease such
as HIV infection, example H.M
 Retrograde amnesia
 Loss of old memories from before a defined event
 Defined event-head injury, lesion, disease onset, e.g. Car accident-don’t
remember what happened before the accident
 The case of N.A.-college student
 Small lesion in the left dorsomedial nucleus of the thalamus
 Retrograde amnesia for the 2 years preceding the accident-fencing sword got
stuck up his nasal passage and affected the brain
 Almost complete anterograde amnesia
 More verbal than visual memory deficits, although both are domains are
affected
Conceptualising memory systems

 Sensory memory
 Duration: milliseconds
 All sensory info you encounter

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