Pharmacology Mental Dental| 204 QUESTION| WITH COMPLETE SOLUTIONS
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Course
Pharmacology Mental Dental
Institution
Pharmacology Mental Dental
Amides are metabolized by Correct Answer: Liver
Correct Answer:
Esters are metabolized by: Correct Answer: Pseudocholinesterase in Plasma
What are the esters: aine Correct Answer: Procaine
Cocaine
Tetracaine
Benzocaine
What amide is safest in children? Correct Answer: Lidocain...
pharmacology mental dental| 204 question| with complete solutions
pharmacology mental dental
esters are metabolized by
what are the esters aine
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Pharmacology Mental Dental| 204
QUESTION| WITH COMPLETE SOLUTIONS
Amides are metabolized by Correct Answer: Liver
Correct Answer:
Esters are metabolized by: Correct Answer: Pseudocholinesterase in Plasma
What are the esters: aine Correct Answer: Procaine
Cocaine
Tetracaine
Benzocaine
What amide is safest in children? Correct Answer: Lidocaine (Xylocaine)
What amide is NOT safe in children and has longest duration of action? Correct
Answer: Bupivicaine (Marcaine)- longest duration
What amide causes the lease amount of vasodilation? Correct Answer:
Mepivicaine (Carbocaine, Polocaine)
What amide can cause methemoglobinemia? Correct Answer: Prilocaine
(Citanest)
Which anesthetic is metabolized in both the liver and the plasma and has the
shortest duration of action? Correct Answer: articaine
LA's are vasodilators in general. Which LA is a vasodilator ? Correct Answer:
ester: cocaine is only vasoconstrictor
LA's are ___ channel blockers Correct Answer: soidum channel blocker s
What form of LA can penetrate neuron membrane? Correct Answer: Non-ionized
(free base) from
,How does a drugs lipid solubility/hydrophobicity effect a drugs potency? Correct
Answer: Increases potency
Increased protein bindings leads to longer/shorter duration of action? Correct
Answer: Longer
Pharmacokinetics
1. Increased blood flow to the site of injection wlll have a ___ duration of action
of the LA
2. Increased lipid solubility will have a more ____ drug and ___ duration of action
(more drug diffuses to hydrophobic layer of membrane if more lipid soluble.
3. A lower pka, higher pH means a __ onset of aciton Correct Answer: 1. shorter
duration
2. potent , longer duration of actoin
3. lower pka, faster onset of action
pka: lowrer the pka, stronger the acid, gives up proton faster, so in non ionized
form
How do vasoconstrictors affect LA? Correct Answer: Prolong Numbness
Reduce Toxicity
Promote hemostasis
, Remember that epi(vasoconstrictors) are going to counter act the vasodilating
properties of local anesthetics Correct Answer:
Max Epi for ASA I patient? Correct Answer: 0.2 mg
Max Epi for cardiac patient? Correct Answer: 0.04mg
Max lidocaine without vasoconstrictor? Correct Answer: 4.4mg/kg
Max lidocaine with vasoconstrictor? Correct Answer: 7mg/kg
rate to inject LA? Correct Answer: 1 carpule per minute
Needle Diameters
30-Gauge -------
27-Guage------
25-Guage------ Correct Answer: 0.3 mm
0.4 mm
0.5 mm
Injection with highest failure rate? Correct Answer: IA nerve block
With IAN give 3/4 carpule
Depth of PSA injection is _____mm Correct Answer: 16 mm
Incisive nerve block is same as the ___ nerve except hold pressure for 2 minutes
after injection to fore aneesthetic into mental formation
Which numbs the actual teeth? Correct Answer: mental foramen
incisive
Block that numbs maxillary anterior and premolars. Also called a true asa block?
Correct Answer: infraorbital
____: blocks soft tissue facial to PM and anterior teeth Correct Answer: mental
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