1.
2.
3.block reuptake of serotonin and norepinephrine
treat depression, anxiety, enuresis in children, ocd, eating disorders
do not give to people with cardiac disease, causes sedation and anticholinergic effects
Amitriptyline, nortriptyline, imipramine, desipramine, clomipramine, doxepin, amoxapine.
Typical Antipsychotics
Direct-acting antispasmotics
Centrally acting muscle relaxants
tricyclic antidepressants
Treat parkinsons by enhancing dopamine
do not give to schizophrenic patients
levodopa (sinemet)
stand up slowly, inhibited by protein
Cholinergic blockers
Serotonergic anxiolytics
Dopaminergics
Phase II
Monitor bp/hr so it's not too low
report difficulty breathing or wheezing
Propranolol Interactions
Mood Disorder Questionnaire
Propanolol other uses
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NR 565 Pharm Midterm 4.
5.
6.Beta Blocker teaching points
Treats anxiety and depression, 5HT agonist and reuptake inhibitor for NE and somo-dendritic reuptake of 5HT
less GI/sexual effects, weight gain, drowsiness
Mirtazapine (Remeron)
Norepinephrine and Serotonin Specific Agonists
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
Direct-acting antispasmotics
norepinephrine-dopamine reuptake inhibitors
a group of second-generation antidepressant drugs that increase serotonin activity specifically, without affecting
other neurotransmitters
Fluoxetine, paroxetine, sertraline, fluvoxamine citalopram, escitalpram
SE: decreased libido, dizziness, weight gain
serotonin syndrome: can be deadly, nausea, diarrhea, chills, sweating, hyperthermia hypertension, myoclonic
jerking, tremor, agitations, ataxia, delerium
Direct-acting antispasmotics
Selective Serotonin Reuptake Inhibitors (SSRIs)
Screen for these to rule them out if depressed
Benzodiazepines
Decreases arterial and venous vasoconstriction
Decreases blood pressure, helps relieve bph, Diuretic may be needed
-osin
alpha 2 agonists
Adrenergic agonists
Beta 1 Antagonist
Alpha 1 Antagonist
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8.
9.
10.Drugs that stimulate and mimic the actions of the sympathetic nervous system. Also called sympathomimetics.
Adrenergic agonists
Muscarinic Agonists
Cholinergic blockers
Alpha 1 Antagonist
Treats spasticity with upper neuron disorders, spinal cord injury, stroke, cerebral palsy, ms
effects calcium, botox inhibits acetylcholine release
dantrolene titrated specially, no CNS depressing drugs, botox can have deadly respiratory response
Dantroline sodium (Dantrium), botulinum toxin type A (Botox)
atypical antipsychotics
Typical Antipsychotics
Direct-acting antispasmotics
Nonbenzodiazepine hypnotics
no accepted medical use in the US it may not be prescribed.
heroin,various opium derivatives,hallucinogenic substances
Schedule I
Phase IV
Schedule IV
Schedule II
Antiplatelet for theumatic fever, tias, coronary artery disease, DVT, decrease MI, fever, mild pain
can cause stomach irritation/ulcer, do not give to children with flu-like/chicken pox because of reye syndrome
Aspirin
Phase III
NSAIDS
Iminostilbenes
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