basophilic stippling of RBCs - diagnosis? - ANSWER lead poisoning
defective dystrophin, less severe than Duchenne's - ANSWER Becker's muscular
dystrophy
LMN CN VII palsy - ANSWER Bell's palsy
Bence Jones proteins - possible diagnoses?
- in each case, what are the proteins? - ANSWER multiple myeloma - kappa or lambda
light chains
Waldenstrom's macroglobulinemia - IgM
IgA nephropathy - diagnosis? - ANSWER Berger's disease
Bernard-Soulier disease - what is the defect? - ANSWER defect in platelet adhesion
"brown tumor" of bone - possible diagnoses?
- what causes the brown color? - ANSWER hyperparathyroidism or osteitis fibrosa
cystica (von Recklinghausen's disease)
- color is due to hemorrhage in cysts
Buerger's disease - what size arteries does it affect? - ANSWER small or medium-artery
vasculitis
Burkitt's lymphoma - what is the translocation?
- what virus is it associated with?
- appearance on histology? - ANSWER 8:14 translocation
EBV
starry sky appearance
Burton's lines - diagnosis? - ANSWER lead poisoning
what types of ANCA are associated with Wegener's granulomatosis and microscopic
polyangiitis? - ANSWER Wegener's - c-ANCA
MPA - p-ANCA
cafe-au-lait spots on skin - diagnosis? - ANSWER neurofibromatosis
Charcot's triad of cholangitis - ANSWER jaundice, RUQ pain, fever
Charcot-Leyden crystals - diagnosis?
- what are they? - ANSWER bronchial asthma - eosinophil membranes
what is the defect in Chediak-Higashi disease? - ANSWER phagocyte deficiency
cherry-red spot on macula - possible diagnoses? - ANSWER Tay-Sachs or Niemann-
Pick disease
, STEP 1 USMLE REVIEW 2022/2023
what are Cheyne-Stokes respirations, and in what circumstance do they occur? -
ANSWER central apnea in CHF and increased intracranial pressure
"chocolate cysts" - ANSWER endometriosis
what does chronic atrophic gastritis predispose to? - ANSWER gastric carcinoma
Chvostek's sign - what is it, and what does it indicate? - ANSWER facial muscle spasm
upon tapping - sign of hypocalcemia
DES exposure in utero predisposes to what? - ANSWER clear cell adenocarcinoma of
the vagina
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