which theory of depression was developed based on observing that patients who were being treated for hep c developed depressive symptoms
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Clinical PMHNP Exam 1 study questions
Which theory of depression was developed based on observing that patients who were being treated for
Hep C developed depressive symptoms?
A. The monoamine theory
B. The inflammation theory
C. The HPA axis theory
D. The stress-diathesis theory correct answer: b. The inflammation theory
Which of the following health conditions have a high co-morbidity with depression?
A. Hypertension
B. Asthma
C. Diabetes mellitus
D. Cardiovascular disease
E. Celiac disease
F. Cognitive impairment
G. Obesity
H. Cancer correct answer: A. Hypertension
C. Diabetes Mellitus
D. Cardiovascular disease
F. Cognitive impairment
G. Obesity
H. Cancer
In the Cutler video on depression, he highlights that there are 200 different ways to meet the diagnostic
criteria for depression.
A. True
B. False correct answer: A. True
You have diagnosed a 53-year-old male with moderate MDD and he has declined psychotherapy but has
agreed to pharmacotherapy. He has diagnoses of Type 2 D.M. with a BMI of 32.1. Which of the following
antidepressants would provide a dual benefit for this patient?
A. Sertraline
B. Fluoxetine
C. Duloxetine
D. Mirtazapine correct answer: C. Duloxetine
Your patient was started on fluoxetine and after ten weeks of treatment his PhQ 9 score is 9. What is
your assessment of the efficacy of treatment based on this score?
A. The patient is in remission
B. The response is adequate but not in remission
C. The response is possibly inadequate
D. The response is inadequate correct answer: B. The response is adequate but not in remission
, In the Star*D trial what percentage of patients treated for depression failed to respond to initial
pharmacotherapy?
A. 20%
B. 30%
C. 40%
D. 50% correct answer: D. 50%
In the Star D trial for patients that achieved remission what percentage relapsed after 4.4 months?
A. 25%
B. 33%
C. 42%
D. 53% correct answer: B. 33%
When should adjunctive therapy be considered in treating MDD? (select all that apply)
A. Already tried 3 or > antidepressants
B. Initial antidepressant well tolerated
C. Partial response (>50% improvement)
D. Specific residual symptoms or side effects that can be targeted
E. Severity of depression, more functional impairment
F. Patient preference correct answer: B. Initial antidepressant well tolerated
D. Specific residual symptoms or side effects that can be targeted
E. Severity of depression, more functional impairment
F. Patient preference
Rates of remission increased with each additional change in therapy, especially when switching.
A. True
B. False correct answer: B. False
You have diagnosed your patient with Major Depressive Disorder and after six weeks of being treated
with fluoxetine 20 mg there is no treatment response. According to the VA/DoD Guidelines for
treatment of MDD what is the next step?
A. Switch to another monotherapy either an antidepressant or psychotherapy.
B. Switch to a different antidepressant
C. Augment with a second antidepressant
D. Augment with a second medication or psychotherapy
A. A, C
B. B
C. C
D. A, D correct answer: D. A,D
Your patient has experienced her first episode of MDD and is in remission. How long should the
antidepressant be continued after remission has been achieved to reduce the risk of relapse?
A. 2 months
B. 4 months
C. 6 months
D. One year correct answer: C. 6 months
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