NR 566 / NR566 Advanced Pharmacology Care of the Family Midterm Review
1. What happens when hormone therapy is stopped in postmenopausal women/ why does it need to be lifelong
- bone mass rapidly decreases by 12%
2. what happens to the bone if there is a lack of estrogen
- bone re...
NR 566 / NR566 Advanced Pharmacology Care of the
Family Midterm Review
1. What happens when hormone therapy is stopped in postmenopausal women/ why does it
need to be lifelong
- bone mass rapidly decreases by 12%
2. what happens to the bone if there is a lack of estrogen
- bone resorption accelerates leading to 12% bone loss in a short period of
time
3. when should progestins not be prescribed during HT
- in women who have undergone a hysterectomy
4. Why would you use IV HT
- only for acute emergent control of heavy uterine bleeding
5. How do Combination OCs reduce fertility
- they inhibit ovulation by suppressing the release of FSH and suppressing
midcycle LH
6. how does the progestin only contraceptive prevent pregnancy?
- mainly by altering cervical secretions making it thicker and having it act as a
barrier to penetration by sperm
- also modifies endometrium making it unfavorable for implantation
7. what should you do if you miss a dose of the mini pill
- if 1 pill is missed take as soon as remembered and use backup contraception
for 2 days resume as scheduled the next day
, - if 2 pills are missed regimen should be restarted and backup contraception
should be used for at least 2 days
8. which cyp450 enzyme is responsible for altering absorption of OC
10. Testosterone replacement therapy use in U.S. and outcome
- For use in male adults who have had a testicular failure
- restores libido, increase ejaculate volume, supports the expression of
secondary sex characteristics
11. will testosterone replacement therapy restore fertility
- no
12. preparations of testosterone replacement
- IM
- nasal gel
- transdermal patch
- transdermal gel
- topical solution
- buccal tab
- subq implant
13. Why is oral testosterone not first-line options?
- the effects are erratic and can pose a risk of hepatotoxicity
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