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BIOS-255 Week 1 Case Study: Coagulation (Already GRADED A)

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Week 1 Case Study: Coagulation BIOS-255: Anatomy & Physiology III w/ LB 1. Discuss which clotting factors the PT and PTT test evaluate and whether each test measures the intrinsic or the extr insic pathways. The Prothrombin Time (PT) Test is used to identify or diagnose blood coagulation disorders ...

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  • April 15, 2022
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  • 2021/2022
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Week 1 Case Study: Coagulation

BIOS-255: Anatomy & Physiology III w/ LB




This study source was downloaded by 100000801755870 from CourseHero.com on 04 -15-2022 11:15:10 GMT -05:00


https://www.coursehero.com/file/109397136/Week-1-Case-Study-KIRBYdocx/

, 1. Discuss which clotting factors the PT and PTT test evaluate and whether each test

measures the intrinsic or the extrinsic pathways.

The Prothrombin Time (PT) Test is used to identify or diagnose blood coagulation disorders or

bleeding problems. Furthermore, there are a variety of reasons why this test is necessary. For

example, when a patient is scheduled for major surgery, it informs the physician if the blood is

clotting properly or if the patient is on warfarin (a blood thinner drug), among other things.

The Prothrombin Time Test is carrying out in a lab/ hospital by a lab technician. The blood is

obtaining from the venipuncture or fingertips and collected in a tube with sodium citrate to avoid

blood cells from the plasma. The plasma is then mixed with tissue factors to test the clotting

time. Thus, this will activate the extrinsic pathway of coagulation which will convert

Prothrombin to Thrombin. In addition, calcium is added to the mixture to counteract the sodium

citrate to allow coagulation to start. Hence, the time of coagulation, adding the calcium to the

time the plasma clot is known as Prothrombin Time.

What can be the Result?

The Prothrombin (PT) Test looks for the presence of the following factors: I (Fibrinogen), II

(Prothrombin), III (Prothrombin), IV (Prothrombin), V (Prothrombin), VI (Prothrombin

(Prothrombin). V, VII, and X are the last three letters of the alphabet. The Prothrombin time will

last around 9-12 seconds if the above factor is present, indicating that the patient has the normal

level of the above clotting factors. A prolonged Prothrombin Time Test will reveal a lack of

factors I, II, V, X, or VII. Liver disease, also known as vitamin K insufficiency. Also, if a patient




This study source was downloaded by 100000801755870 from CourseHero.com on 04 -15-2022 11:15:10 GMT -05:00


https://www.coursehero.com/file/109397136/Week-1-Case-Study-KIRBYdocx/

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