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ASSESSMENT OF ACID-BASE BALANCE RT 3025 HYDROGEN ION CONCENTRATION (pH)

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ASSESSMENT OF ACID-BASE BALANCE RT 3025 HYDROGEN ION CONCENTRATION (pH)  Normal pH: 7.35 - 7.45  pH is measurement of H+ ions in the plasma.  Changes in pH of 1 unit represent a ten fold change in [H+]. pH [H+] in nanomols/ L 7.6 26 7.5 32 7.4 40 7.3 50 7.2 63 7.1 80 7....

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  • April 6, 2022
  • 74
  • 2021/2022
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ASSESSMENT OF ACID-BASE
BALANCE




RT 3025

,HYDROGEN ION CONCENTRATION
(pH)
 Normal pH: 7.35 - 7.45
 pH is measurement of H+ ions in the plasma.

 Changes in pH of 1 unit represent a ten fold change in

[H+].

pH [H+] in nanomols/ L
7.6 26
7.5 32
7.4 40
7.3 50
7.2 63
7.1 80
7.0 100
6.9 125

, ACIDEMIA VS ALKALEMIA
 pH > 7.45 = alkalemia.
 pH < 7.35 = acidemia.


 Allbody functions occur optimally around a pH of
7.40.
 Acidosis results in depression of the CNS.
Lethargic and disoriented to comatose.
 Acidosis reduces cardiac contractility.
 Alkalosis results in hyperexcitability of CNS and
peripheral nerves.
 muscle spasm.

, PaCO2
 Normal value: 35-45 mmHg.
 It is the most reliable measurement for evaluating
effectiveness of ventilation.
 It is a reflection of the respiratory component of the acid-
base status.
 CO2 is a waste product of metabolism; therefore, PaCO 2
identifies degree of ventilation in relation to metabolic
rate.
 Fever or exercise increase metabolic rate (CO2
production) leading to hyperventilation (CO2 elimination).

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