NR 507 Midterm Practice Questions & Answers (View Questions
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Course
NR 507 / NR507
Institution
Chamberlain College Nursing
NR 507 Midterm Practice Questions & Answers (View Questions)
Epigenetics
Defects in the encoding of histone-modifying proteins
Housekeeping Genes are vital to the function and maintenance of all the body’s cells. What characteristic is associated with these genes?
They lack encoding hi...
nr 507 midterm practice questions amp answers view questions
nr 507 midterm practice questions amp answers view questions epigenetics defects in the encoding of histone modifying proteins ho
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NR 507 / NR507
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NR 507 Midterm Practice Questions & Answers (View
Questions )
Epigenetics
Defects in the encoding of histone-modifying proteins
Housekeeping Genes are vital to the function and maintenance of all the body’s cells. What characteristic
is associated with these genes?
They lack encoding histones
Mutations in the encoding of histone modifying proteins have been shown to influence the development
of what congenital condition?
Acephalous
Epigenetics refers to chemical modification that are made to what?
Both the DNA and the histones
Signals to change or modify epigenetic tags are received from where?
Contact with other cells, hormones and environmental factors.
What sort of molecule is responsible for transferring signals into cells to gen regulatory proteins?
Proteins
Mutations in the encoding of histone-modification proteins have been shown to influence the
development of what congenial condition?
Heart Disease
Epigenetics and its role on human development
Research has provided support for the theory that epigenetic modification can result from deficient in
utero nutrition causing?
Obesity, cardiovascular disease, and diabetes
During which stage of human development does the role of epigenetics have the greatest impact on the
development of epigenetic abnormalities?
In utero
The difference between DNA sequence mutations and epigenetic modifications is?
Epigenetic modification can be reversed.
Research has provided support for the theory that epigenetic modification can result from deficient in
utero nutrition causing which chronic disease?
Obesity, cardiovascular disease and diabetes
Totipotent cells and its ability to differentiate into any type of cell
Which embryonic stem cell characteristic is referred to as a totipotent?
Ability to differentiate into any type of somatic cell
Examples of two totipotent cells are?
A zygote and Cells in the early embryo up to 5 days
What is a Totipotent cell?
Totipotent cells are cells that are able to develop into any type of cell found in the body.
Are all cells Totipotent cells?
No. Only the fertilized egg and the cells produced by the first few cell divisions (in the Embryonic
Development phase) are Totipotent cells.
Prader-Willi syndrome and Angelman syndrome?
What characteristic of Prader-Willi syndrome is not a characteristic of Angelman syndrome?
it is inherited from the father
A child with Prader-Willi syndrome has been hospitalized. Which assessment findings does the nurse
expect with this syndrome?
1
, Insatiable hunger
The nurse is examining an 8-year-old boy with chromosomal abnormalities. Which sign or symptom
suggests the boy has Angelman syndrome?
Observation shows jerky ataxic movement similar to a puppet's gait.
Cellular Proliferation
5-Azacytidine and the treatment of cancer
What is 5-azacytidine? Nucleoside analog able to be incorporated into RNA & DNA
5- Azactytide has demonstrated promise in the treatment of which form of cancer?
Pancreatic
the role of inactive MLH1 in the development of some forms of inherited colon cancer
What is the role of inactive MLH1 in the development of some forms of inherited colon cancer? DNA damage
is left unrepaired
Effects of ethanol on neural stem cells ability to differentiate into functional neurons-
Research has demonstrated that neural stem cells have an impaired ability to differentiate into functional
neurons when subjected to?
Ethanol
Inflammation as an etiology for cancer-note conditions in which this may occur
What chronic inflammatory conditions can increase risk for cancer?
HIV, hepatitis, h-pylori, bronchitis, pancreatitis
Cancer
In terms of epigenetic modifications, the role of environmental stressors associated with development of cancer
When considering abnormal epigenetics modifications, what factor is currently being viewed as strongly
associated with the development of some cancers? Environmental stressors
Defects in Mechanism of Defense
Hemolytic defects in the newborn
To explain hemolytic disorders in the new born to new parents, the nurse who cares for the new born
population must be aware of the physiologic characteristics related to these conditions. What is the most
common cause of pathologic hyperbilirubinemia? Hemolytic disorders
Which infant is most likely to express Rh incompatibility? Infant of an Rh- negative mother and a father who
is Rh Positive and homozygous for the Rh factor
Rh hemolytic disease is suspected in a mother's second baby, a son. Which factor is important in
understanding how this could develop?
The first child was Rh positive
The nurse is caring for an infant with hemolytic disease. Which medication should the nurse anticipate to be
prescribed to decrease the bilirubin level?
Phenobarbital
A newborn is found to have hemolytic disease. Which combination would be found related to the blood types
of this newborn and the parents of the newborn?
Newborn who is Type A, mother who is type O
The nurse is caring for a newborn with hemolytic disease of the newborn who is receiving phototherapy.
Which nursing intervention would be the most appropriate for the nurse to do?
The nurse turns the newborn every 3 to 4 hours
Understand the meaning of infectivity
2
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