The culture and sensitivity testing of a patient's wound exudate indicates that a specific
antibiotic is necessary for treatment. The United States Pharmacopeia–National Formulary
indicates that the drug in question is 96% protein bound. What are the implications of this
fact?
Response A drug that is 96% protein bound has only 4% of ingested molecules free and
Feedback: active, a fact that is likely to necessitate a high dose of the drug. This does
not result in rapid absorption and/or excretion and does not indicate a need
for increased protein intake.
Question 2
1 out of 1 points
During a clinic visit, a patient complains of having frequent muscle cramps in her legs. The
nurse's assessment reveals that the patient has been taking over-the-counter laxatives for the
past 7 years. The nurse informed the patient that prolonged use of laxatives
Response Long-term intake of laxatives, antidepressants, and antibiotics has been found
Feedback: to deprive a person of most essential nutrients, such as vitamins. Prolonged
use of laxatives is not known to turn urine acidic, cause urinary tract
infections, counter the effect of other drugs, or inhibit the biotransformation
of drugs.
Question 3
1 out of 1 points
A patient with a recent diagnosis of acute renal failure has a long-standing seizure disorder
which has been successfully controlled for several years with antiseizure medications. The
nurse should recognize that the patient's compromised renal function will likely
Response Impaired renal function will increase the half-life of drugs that are
Feedback: metabolized by the kidneys. This does not necessarily render such
medications ineffective and it does not decrease the first-pass effect. IV
administration will not compensate for the patient's impaired renal function.
Question 4
, 1 out of 1 points
A patient has been prescribed several drugs and fluids to be given intravenously. Before the
nurse starts the intravenous administration, a priority assessment of the patient will be to note
the
Response Baseline body weight and height, heart rate, and blood pressure are all
Feedback: important considerations during the assessment of a patient. However, if a
patient has to be given drugs intravenously, it is important to inspect the skin
for rashes, moles, or sores, so those areas can be avoided as an insertion or
injection site.
Question 5
1 out of 1 points
A nurse is caring for a patient who has had part of her small intestine removed due to cancer.
She has also now developed hypertension and has been prescribed a new medication to
decrease her blood pressure. While planning the patient's care, the nurse should consider a
possible alteration in which of the following aspects of pharmacokinetics?
Response Because absorption takes place mostly in the small intestine, there could be
Feedback: possible alterations with this process. Distribution takes place in the blood
vessels; metabolism in the liver; and elimination via the kidneys. Because
these systems are not affected by her surgery, these phases of
pharmacokinetics would not be altered.
Question 6
1 out of 1 points
A patient who has been admitted to the hospital for a mastectomy has stated that she has
experienced adverse drug effects at various times during her life. Which of the following
strategies should the nurse prioritize in order to minimize the potential of adverse drug effects
during the patient's stay in the hospital?
Response In an effort to minimize the potential of adverse drug effects, it is necessary to
Feedback: closely monitor the patient. It would be inappropriate for the nurse to alter the
route or frequency of administration or to encourage herbal remedies that also
carry the potential for adverse effects.
Question 7
1 out of 1 points
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