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Rasmussen College: MDC III NUR2759MCD4_work_and_class_LATEST UPDATED,100% CORRECT

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Rasmussen College: MDC III NUR2759MCD4_work_and_class_LATEST UPDATED Diseases of the Peripheral Nervous System Guillain-Barre Syndrome Guillain-Barre Syndrome (GBS) is a result of overactive immunity. It is rare and affects men more than women. The myelin sheath is attacked by circula...

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  • March 12, 2022
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Rasmussen College: MDC III NUR2759MCD4_work_and_class_LATEST
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Diseases of the Peripheral Nervous System


Guillain-Barre Syndrome
Guillain-Barre Syndrome (GBS) is a result of overactive immunity. It is rare and
affects men more than women. The myelin sheath is attacked by circulating
antibodies resulting from an immune response. There are various triggers from
bacterial to viral. The most common presentation is a viral-like illness one to three
weeks prior to GBS symptoms. The result of the overactive immunity results in
destruction of the myelin sheath which slows the transmission of impulse from
node-to-node. The slowing of impulses produces the symptoms of GBS. The
hallmark of the disease is ascending weakness.
Stages of GBS
Acute Stage – Onset of symptoms
Plateau – Symptoms remain for a few days to

a few weeks Recovery

May take up to 2

years Diagnostics

Lumbar puncture to evaluate cerebral spinal fluid (CSF) for increase in

,protein--results are non- conclusive
Electrophysiologic studies (EPSs)--demonstrates demyelinating

neuropathy Treatment Options

Plasmapheresis – Remove circulating

antibodies Start within several days

of onset of illness

,3 to 4 treatments – 1-to-2 days apart
Weigh the client before and after

procedure IV immunoglobulin

(IVIG)
Is as effective as Plasmapheresis
Infuse slowly observing for any side and

adverse effects Nursing Care

Frequent monitoring of the respiratory and

cardiovascular system Inability to maintain airway--

potentially fatal with ascending paralysis Aspiration

precautions

Suction equipment at the

bedside HOB elevated 45

degrees
Change position every 2 hours
Breathing exercises, cough and deep

breathing Incentive spirometer
Oxygen
Report change in HR and BP to primary

healthcare provider Interdisciplinary –

Respiratory therapy
Chest physiotherapy
Managing airway if

compromise occurs Oxygen

During the recovering period involve

, other disciplines PT/OT

Speech

therapy

Nutritionist

Myasthenia

Gravis

Myasthenia Gravis is a progressive-acquired autoimmune disease. It is a
breakdown in the relaying of signals from the nerves to the muscles. This
breakdown in communication at the synapses causes muscle weakness. The typical
area where symptoms are first noticed is visual disturbances. Other symptoms can
include drooping of the eyelids and difficulty swallowing. Death can result from a
rapid development of muscle weakness which can induce respiratory failure.

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