Function of immune system
1st line of defense
o Skin/mucous membranes
o Passive immunity from mom
o Maternal circulation/breast milk
Cannot produce immunoglobulins (antibodies)
Until approx. 2 mos. of age
Immune system not fully functional until 6 years of age
Those babies that are breast fed, usually have less ear infections
Stimulates production of antibodies against a specific foreign substance (antigen)
Contraindications
o Anaphylaxis
o High doses of steroids (<14 days)
o Acute febrile illness – greater than 39
o Common cold/minor illness NOT contraindicated
o Chronic illness (cancer)
o Taking immunosuppressive drugs
o Egg allergy – flu shots
o Most up to date schedules on CDC.gov
Purpose of vaccines, misconceptions
Misconceptions
o Causes autism
o Rotovirus vaccine is dangerous
o Vaccines have toxic ingredients – led and mercury
o Vaccines can fail
o Vaccines can cause the actual illness
o Parents can refuse vaccines
Types
o Live (attenuated) – vaccines made from virus made from live virus
o Killed (inactivated viruses)
o Toxoids – diphtheria, tenus, - one type of vaccine – based on the toxin made
from the bacteria
o Human immune globulin – Igg Ige – weakened immune system and this helps
them bring up their immune system
o Herd immunity – vaccinate many to protect the few
Communicability periods of disease
Incubation period – common cold = 1-5 days
o Time of exposure to the time the time symptoms arrive
, o Chicken pox = 21 days
Period of communicability – time it takes to transfer a disease from me to you
Prodromal period – beginings off an illness – feeling eh, scratchy throat
Sometimes difficult to tell the difference
Virus
o Increased lymphocytes
Bacteria
o Increased neutrophils
o Left shift – some of the white blood cells shift to make it look bacterial infection
Common viral and bacterial infections, treatment, and nursing care
viral
Gastroenteritis
o Vomiting/diarrhea
Volume depletion
Intravascular space
o Degree of dehydration
Determined by physical exam
Signs of dehydration – clammy – dry mucus membranes, dry skins
o Treatment
Mild/moderate
Zofran (ondansetron)
Oral hydration
Severe
IV 20cc/kg isotonic solution
Coxsackie disease (infants and young children)
o Hand/foot/ and mount disease
Fever
Sore throat
Malaise
Poor appetite
Rash and mouth sores occur 1-2 days after the above symptoms
Lasts about 1 week
Conjunctivitis – pink eye – last 7-10 days
Thrush
o Yeast infection
Oral (infants)
Urogenital (infants/toddlers; diaper dermatitis)
“Yeast infection” (adolescent girls)
Intertrigo (skin folds of groin, armpits, torso)
o Treatment
Hygiene (limit moisture diaper area)
Topical/systemic antifungals (nystatin)
, 5th disease
o Fever
o Runny nose
o Headache
o Rash (slapped cheek) then spreads (comes and goes)
o May last 2-39 days
Chicken pox
Measles, mumps, rubella
Roseola (6-18 months)
o Sudden high fever (39.4-41.1) 3-5 days
o Rash several hours to 2 days after fever is gone
Blanches with pressure
Neck and trunk, may have whitish ring, lasts 24-48 hrs
Monomucleosis (Epstein- Barr virus)
o Causes
Fever
Fatiguge
Sore throat
Swlooen glands
Many have a rash (exanthem)
Most have fever
Most are accompanied by cold or flulike symptoms
Most transmitted by direct contact with droplets or airborne particles
Most can be prevented by immunization
Treatment is mostly symptomatic
Encephalitis is rare but can occur as a complication of most childhood viral infections
Febrile seizures (most common from 3 months-5 yrs)
Bacterial
Strep throat /scarlet fever
Lyme disease (most common tic-borne disease)
o Affects skin, musculoskeletal, CV, neuro systems
Early: Vague flu-like symptoms/”bulls-eye” rash
Neuro: Headaches, bell’s palsy, ataxia
Musculoskeletal: Large joint arthritis (knee), joint/muscle pain
Pertussis (Whooping cough)
o Catarrhal stage
1-2 weeks
URI symptoms
Paroxysmal
2-4 weeks or longer
Increased severity of cough (whoop sound). Cyanosis, distention of neck
veins, salivation, tongue protrusion
, o Convalescent
1-2 weeks
Symptoms lessen, cough may persist for months
Helminths (Worms)
o Transmission
Oral-fecal
Ingestion contaminated host
Skin penetration
Bite of blood-sucking insect
o Treatment
Entire family
Prevention
Anti-worm meds po
Bacterial meningitis
o Acute inflammation of meninges
Bacteria enters subarachnoid space
Inflammation response triggered
Causes obstruction of blood flow
Increased ICP
Seizures
Hernation
Death
o Infants <32 weeks gestation most at risk
Temp instability
Bulging anterior fontanel
Shrill cry/irritability
Gaze deviation
Posturing/seizures
NO nuchal rigidity
o Older child
Fever
Headache
Meningeal signs
Brudzinski sign
Kernig’s sign
Nuchal rigidity
Most reliable
Bacterial infections
o Older child
Photophobia
Vomiting
Behavior changes
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