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NR283 Patho Exam 1 Study Guide (Latest-2022) / NR 283 Patho Exam 1 Study Guide /NR283 Exam 1 Study Guide / NR 283 Exam 1 Study Guide: Chamberlain College of Nursing | Complete and Latest Guide |

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NR283 Patho Exam 1 Study Guide (Latest-2022) / NR 283 Patho Exam 1 Study Guide /NR283 Exam 1 Study Guide / NR 283 Exam 1 Study Guide: Chamberlain College of Nursing | Complete and Latest Guide |

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,•An initial latent or ―silent‖ stage, in which no clinical signs are evident, characterizes some

diseases. In infectious diseases this stage may be referred to as the incubation period, which is

the time between exposure to the microorganism and the onset of signs or symptoms; it may last

for a day or so or may be prolonged, perhaps for days or weeks. Often the disease agent may be

communicable during this incubation period.


•The prodromal period comprises the time in the early development of a disease when one is

aware of a change in the body, but the signs are nonspecific; for example, fatigue, loss of

appetite, or headache. A sense of feeling threatened often develops in the early stage of

infections. Laboratory tests are negative during the prodromal period; thus it is difficult to

confirm a diagnosis.


•The manifestations of a disease are the clinical evidence or effects, the signs and symptoms, of

disease. These manifestations, such as redness and swelling, may be local, or found at the site of

the problem. Or signs and symptoms may be systemic, meaning they are general indicators of

illness, such as fever.


•Signs are objective indicators of disease that are obvious to someone other than the affected

individual. Examples of a sign are a fever or a skin rash.


•Symptoms are subjective feelings, such as pain or nausea. Both signs and symptoms are

significant in diagnosing a particular problem.


•Lesion is the term used to describe a specific local change in the tissue. Such a change may be

microscopic, as when liver cells are examined for pathologic change, or highly visible, such as a

blister or pimple observed on the skin.

,•A syndrome is a collection of signs and symptoms, often affecting more than one organ, that

usually occur together in response to a certain condition.


•Diagnostic tests are laboratory tests that assist in the diagnosis of a specific disease. The

appropriate tests are ordered on the basis of the patient's manifestations and medical history, the

clinical examination, and the patient's answers to specific questions. These tests may also be

used for monitoring the response to treatment or the progress of the disease. Such tests may

involve chemical analysis of body fluids such as blood, examination of tissues and cells from

specimens (e.g., biopsies or body secretions), identification of microorganisms in body fluids or

tissue specimens, or radiologic examination of the body. It is important that medical laboratories

have a Quality Assurance (QA) program in place to ensure accurate test results. Also, it is often

helpful for a patient to have any future or repeated tests done by the same laboratory to provide a

more accurate comparison of results.


•Remissions and exacerbations may mark the course or progress of a disease. During a

remission, the manifestations of the disease subside, whereas during an exacerbation the signs

increase. Rheumatoid arthritis typically has periods of remission when pain and swelling are

minimal, alternating with acute periods when swelling and pain are severe.


•A precipitating factor is a condition that triggers an acute episode, such as a seizure in an

individual with a seizure disorder. Note that a precipitating factor differs from a predisposing

factor. For example, a patient may be predisposed to coronary artery disease and angina because

of a high-cholesterol diet. An angina attack can be precipitated by shoveling snow on a very cold

day.

, •Complications are new secondary or additional problems that arise after the original disease

begins. For example, following a heart attack, a person may develop congestive heart failure, a

complication.


•Therapy or therapeutic interventions are treatment measures used to promote recovery or slow

the progress of a disease. These measures may include surgery, drugs, physiotherapy, alternative

therapies or behavior modification (see Chapter 3).


•Sequelae describe the potential unwanted outcomes of the primary condition, such as paralysis

following recovery from a stroke.


•Convalescence or rehabilitation is the period of recovery and return to the normal healthy state;

it may last for several days or months.




Systemic signs of disease

Include signs and symptoms common to significant infections in any area of the body. Fever,

fatigue and weakness, headache, and nausea are all commonly associated with infection.


Disease Prevention- (Primary prevention examples)

Primary Prevention


The goal is to protect healthy people from developing a disease or experiencing an injury in the

first place. For example:


•Education about good nutrition, the importance of regular exercise, and the dangers of tobacco,

alcohol, and other drugs

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