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APB- Neuron Function POGIL

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APB- Neuron Function POGIL

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  • February 2, 2022
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  • 2022/2023
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Neuron Function
How does a signal travel across and between neurons?

Why?
Just as the coaxial cables that run down your street or through your house carry television and Internet
signals, the job of a neuron is to move an electrical signal from one place to another in order to send sen-
sory messages throughout the body. In a previous activity you saw how a membrane potential is formed
both at rest and during an inflow of ions. In this activity you will explore how changes in membrane
potentials can propagate a signal down the axon of a neuron.

1. Which of the gated embedded proteins in Model 1 allow sodium ions ( ) through the membrane?


2. Which of the gated embedded proteins in Model 1 allow potassium ions ( ) through the membrane?


3. The neuron illustrated in Model 1 has received a signal from either a sensory cell (taste bud, skin
cell, retinal cell, etc.) or from another neuron. What evidence do you find in diagram 1 of the
model that indicates a signal has been received?


4. In diagram 2 of Model 1, gated embedded protein B has opened. Was this opening triggered by
the arrival of a signal ligand? If no, propose an alternate stimulus that might have triggered the
gate to open.



5. Consider Model 1.
a. When a signal moves down the axon of the neuron, which direction do sodium ions move
through the voltage-gated embedded proteins?


b. What does the movement of sodium ions across the membrane do to the membrane potential
near the open embedded protein?


6. Consider Model 1.
a. When a signal moves through the axon of the neuron, which direction do potassium ions
move through the voltage-gated embedded proteins?


b. What does the movement of potassium ions across the membrane do to the membrane poten-
tial near the open embedded protein?




Neuron Function
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1

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, G




G




G
+30 mV
–55 mV




+35 mV
F




F




F
E
E




E




–80 mV
+35 mV
+30 mV

D




D




D
C
C




C
+35 mV




–70 mV
–80 mV




B
B




B




A
A




A
4




5




6
G




G
G
–70 mV




–70 mV




–60 mV
F




F
F
E




E
E
–70 mV




–60 mV




–55 mV
Model 1 – An Action Potential




D




D
D
C




C
C
–60 mV




–55 mV




+30 mV
B




B
B
A




A
A
Outside
of cell




of cell
Inside
1




2




3




2 POGIL™ Activities for AP* Biology
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