Summary
Summary Lecture 10 Energy Metabolism of the heart
- Course
- Institution
This is a summary of lecture 10 Energy Metabolism of the heart. With all of my summaries for this course I passed it with an 8!
[Show more]
Seller
Follow
biomedicalsciencesvu
Reviews received
Content preview
Lecture 10 Energy metabolism of the heartWhy do we have a sophisticated (geavanceerd) sytem?
Transport of oxygen
Removal of waste products
PART 1 Arrangement of the cardiovascular system
1. Oxygen pressure (mmHg); high where we inhale the air
and it decreases when oxygen is taken
a. Pressure at right ventricle is 40mmHg or 15mmHg
in exercise because then more oxygen is extracted
by the circulation
2. Systolic and diastolic pressures (mmHg)
a. Left ventricle: systolic 120, diastolic 80
b. Right ventricle: systolic 25, diastolic 4
So, mean arterial pressure in systemic circulation is higher than in
pulmonary circulation
In series: 2 pumps (left and right side of the heart) – output of both sides of the
heart do closely match
In parallel: most major organs except the liver – enables adaptations to
specific needs in blood flow, without affecting blood flow in other organs
The demands of the body do differ in different species and the
arrangement of the cardiovascular system is different.
Mammals and birds have a 4 camber heart. Crocodiles can
lower their metabolic rate when they dive into the water. Due to
the lower metabolic rate the heart beat lowers too and they
only use blood with lower oxygen content.
Flow of oxygen
Take up oxygen in our lungs inspire that pulmonary
circulation oxygen flows in the heart systemic
circulation oxygen reached the muscles (sarcomeres
(smallest contractile unit in muscle) where it can be
consumed mitochondria ATP
Actin: thin filament
Myosin: thick filament
Tropomyosin: decorate the thin filament and blocks the binding sites
of myosin on actin
Troponin: molecular switch or Ca to bind—once bind tropomyosin will
roll over actin and expose binding sites
Muscle contraction:
Electrical stimulus cell depolarize Ca release from SR Ca bind to troponin
tropomyosin moves away from the actin myosin bind to actin force is generated
and muscle and contract
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller biomedicalsciencesvu. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $3.25. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79373 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now