ONC/ONCC Chemotherapy Immunotherapy Certificate Q&A Exam Bundle

when chemo is used before primary treatment (surgery) to reduce the size of a tumor neoadjuvant therapy neoadjuvant therapy is common for what 2 kind of cancers? colon and breast when chemo is used after primary (surgery, radiation) adjuvant induction start of chemo consolidation testing...

vesicants bleomycin, carmustine, cisplatin, daunorubicin, doxorubicin, etposide, idarubicin, melphalan, taxol, vincristine cisplatin antidote sodium thiosulfate doxorubicin antidote Dexrazoxane vincristine antidote hyaluronidase Alkylating agents busulfan, cytoxan, melphalan, ifosfamide,...

Cancer Epidemiology Study of the distribution and determinants of cancer in population groups Global Cancer Statistics cancer is the leading cause of disease worldwide Cancer rate suppouse to increase by 75% to 22 M new cases in 2030 Causes of cancer rate increase because of increasing to...

Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy Ma...

TotectAnecdote for Doxorubicin Warm CompressPlant alkaloids and etoposide Bleomycinbad for the lungs Leucovorinpotentiates the effects of 5-FU and decreases the effect of MTX Calvert Formula ComponentsArea under the curve (AUC) Carboplatin Creatinine Clearance Aromatase Inhibitorsus...

When a DNA segment of a gene is copied incorrectly and located next to a proto-oncogene, the mutation can become: a) an oncogene b) a tumor suppressor gene c) a DNA repair gene d) a differentiation gene a) an oncogene What teaching is included regarding nausea and vomiting for a patient wit...

Predictors of PDL1/PD1 inhibitor response Presence of tumor CD8 cell infiltration High cancer genome burden High levels of cancer PD-L1 expression (PD1 is on the cytotoxic T cell) Ipilimumab CTLA4 inhibitor Nivolumab PD-1 inhibitor Regorafenib VEGF inhibitor Bevacizumab Monoclonal a...

Hematologic cancer (blood cancer) -cancer that begins in bone marrow or immune system cells. -Ex: leukemia, lymphoma, multiple myeloma Leukemia cancer starts in blood-forming tissues like bone marrow -causes lots of abnormal blood cells to be produced and enter bloodstream Lymphoma -cancer t...

How targeted therapy and chemo differ -targeted therapies act on specific molecular targets on or within the cells that are associated with cancer, whereas standard chemo act on all rapidly dividing cells-chemo has more SEs-targeted therapy ae chosen and designed to interact with their target on or ...

What do alkylating chemotherapy drugs do? Chemotherapy drugs that are cell cycle nonspecific, so they exert their effects in all phases of the cell cycle. They directly damage DNA to prevent cancer cells from reproducing. They cause breaks in the DNA or cross-linking in a process called alkylation, ...

The Normal Cell Cycle -The cell cycle refers to the ordered seres of processes of DNA replication and mitosis, or cell division -Cell nucleus regulates these processes by gathering and processing complexes molecular information Interphase and Mitotic Phase Cell division produces two identical ...

3 major phases of cell division: Interphase Mitotic phase Cytokinesis 3 steps of interphase: First growth phase (G1) Synthesis phase (S phase) Second growth phase (G2) 4 phases of mitosis: Prophase Metaphase Anaphase Telophase Innate immunity: Non-specific response, either: 1. Barri...