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[Show more]Phase 1 - Evaluate safety, 40-50 healthy volunteers 
Phase 2 - Evaluate efficacy, 10-100 patients 
Phase 3 - Statistical analysis of safety & efficacy, double blinded RCT 
Phase 4 - post marketing surveillance 
Absorption - The movement of a drug from the site of administration into circulation 
Bio...
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Add to cartPhase 1 - Evaluate safety, 40-50 healthy volunteers 
Phase 2 - Evaluate efficacy, 10-100 patients 
Phase 3 - Statistical analysis of safety & efficacy, double blinded RCT 
Phase 4 - post marketing surveillance 
Absorption - The movement of a drug from the site of administration into circulation 
Bio...
Anti-Ulcer drugs help by: - Answer--altering gastric pH by decreasing acid secretion 
-protecting the stomach wall lining by increasing mucosal protection 
-eradicating harmful bacteria Ex: H. Pylori 
What are the main pharmacologic categories of drugs we used to manage gastric acid secretion and 
t...
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Add to cartAnti-Ulcer drugs help by: - Answer--altering gastric pH by decreasing acid secretion 
-protecting the stomach wall lining by increasing mucosal protection 
-eradicating harmful bacteria Ex: H. Pylori 
What are the main pharmacologic categories of drugs we used to manage gastric acid secretion and 
t...
Grapefruit juice - Answer-CYP 450 inhibitor 
- Intake leads to increased pharmacologic effect of drugs 
Warfarin - Answer-Interacts with TMP-SMX, erythromycin, Flagyl, Diflucan 
=> Increases INR 
(Increased bleeding and hemorrhaging) 
Tetracycline - Answer-- Do not take with milk products 
Clarit...
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Add to cartGrapefruit juice - Answer-CYP 450 inhibitor 
- Intake leads to increased pharmacologic effect of drugs 
Warfarin - Answer-Interacts with TMP-SMX, erythromycin, Flagyl, Diflucan 
=> Increases INR 
(Increased bleeding and hemorrhaging) 
Tetracycline - Answer-- Do not take with milk products 
Clarit...
grapefruit juice can _____levels of other drugs that use the CYP450 pathway - Answer-increase 
grapefruit juice is an - Answer-inhibitor 
Amount of refills for schedule II drug - Answer-no refills-- must be rewritten every time 
broad-spectrum abx increase risk for - Answer-superinfection 
____ gen ...
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Add to cartgrapefruit juice can _____levels of other drugs that use the CYP450 pathway - Answer-increase 
grapefruit juice is an - Answer-inhibitor 
Amount of refills for schedule II drug - Answer-no refills-- must be rewritten every time 
broad-spectrum abx increase risk for - Answer-superinfection 
____ gen ...
First line for tx of constipation in pregnancy? - Answer-bulk forming laxatives (citrucel) and glycerin 
suppositories. 
which constipation tx is contraindicated in pregnancy? - Answer-Castor Oil is category X; rectal 
enemas are contraindicated 
Contraindications of Calciu carbonate antacids? - Ans...
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Add to cartFirst line for tx of constipation in pregnancy? - Answer-bulk forming laxatives (citrucel) and glycerin 
suppositories. 
which constipation tx is contraindicated in pregnancy? - Answer-Castor Oil is category X; rectal 
enemas are contraindicated 
Contraindications of Calciu carbonate antacids? - Ans...
Understand and identify evidenced-based prescribing resources - Answer-ACOG, American Ca 
Society, National lung and heart instituete, EEP, Dynamed, Lexicomp, Sanford guide, lactamed **NO 
PDR 
Understand PLLR: Drugs in Pregnancy and Lactation: Improved Benefit-Risk information. - AnswerJune 2015; 3...
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Add to cartUnderstand and identify evidenced-based prescribing resources - Answer-ACOG, American Ca 
Society, National lung and heart instituete, EEP, Dynamed, Lexicomp, Sanford guide, lactamed **NO 
PDR 
Understand PLLR: Drugs in Pregnancy and Lactation: Improved Benefit-Risk information. - AnswerJune 2015; 3...
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