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A PACKAGE DEAL OF NR- 565 COMPREHENSIVE EXAMINATIONS 2024 ( QUESTION & ANSWER)
A PACKAGE DEAL OF NR- 565 COMPREHENSIVE EXAMINATIONS 2024 ( QUESTION & ANSWER)
[Show more]A PACKAGE DEAL OF NR- 565 COMPREHENSIVE EXAMINATIONS 2024 ( QUESTION & ANSWER)
[Show more]NR 565 - advanced pharmacology midterm exam 2024 
What is the CYP450 (cytochrome P450) 
liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interactions 
 
 
 
CYP450 inducers 
Speed up metabolism of drugs (drug is cleared faster), drug ha...
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What is the CYP450 (cytochrome P450) 
liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interactions 
 
 
 
CYP450 inducers 
Speed up metabolism of drugs (drug is cleared faster), drug ha...
NR 565 Midterm Study Guide 2024 
drug schedules - schedule I 
Drug Schedules 
 
no currently accepted medical use and for research use only 
 
high potential for abuse 
 
examples: 
heroin 
LSD 
MDMA (3,4-Methyl​enedioxy​methamphetamine: AKA ecstasy) 
 
 
 
drug schedules - schedule 2 
combinati...
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drug schedules - schedule I 
Drug Schedules 
 
no currently accepted medical use and for research use only 
 
high potential for abuse 
 
examples: 
heroin 
LSD 
MDMA (3,4-Methyl​enedioxy​methamphetamine: AKA ecstasy) 
 
 
 
drug schedules - schedule 2 
combinati...
Advance Pharmacy NR565 comprehensive exam 2024 
 Which schedule drugs can APRNs prescribe? 
Schedule II-V 
 
 
 
· Who determines and regulates prescriptive authority? 
Nurse practitioner scope of practice is determined by state practice and licensure laws. 
 
 
 
· How does limited prescriptive a...
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 Which schedule drugs can APRNs prescribe? 
Schedule II-V 
 
 
 
· Who determines and regulates prescriptive authority? 
Nurse practitioner scope of practice is determined by state practice and licensure laws. 
 
 
 
· How does limited prescriptive a...
NR 565 Pharm Midterm Study Guide 2024 
Rheumatoid arthritis meds contraindicated in pregnancy? 
Methotrexate, Leflunomide, & Biologic response modifiers (-ab, ib). NSAIDs and prednisone are less dangerous. 
 
 
 
Which dietary supplement can interfere with absorption of Ibandronate? 
Calcium 
 
 
 
...
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Rheumatoid arthritis meds contraindicated in pregnancy? 
Methotrexate, Leflunomide, & Biologic response modifiers (-ab, ib). NSAIDs and prednisone are less dangerous. 
 
 
 
Which dietary supplement can interfere with absorption of Ibandronate? 
Calcium 
 
 
 
...
NR565 Advanced Pharm Midterm 2024 
Who determines and regulates prescriptive authority? 
Determines: Also known as independent prescribing. APRNS can prescribe without limitation and is state dependent. Includes "legend" (prescription) and controlled drugs, health/medical services, DME, etc. 
Regu...
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Who determines and regulates prescriptive authority? 
Determines: Also known as independent prescribing. APRNS can prescribe without limitation and is state dependent. Includes "legend" (prescription) and controlled drugs, health/medical services, DME, etc. 
Regu...
NR565 Midterm Study guide exam 2024 
promoting positive outcomes through prudent prescribing practices 
Administering medications and prescribing medications are two distinct processes. Prescription writing requires prudent and deliberate decision-making processes to maintain patient safety and redu...
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promoting positive outcomes through prudent prescribing practices 
Administering medications and prescribing medications are two distinct processes. Prescription writing requires prudent and deliberate decision-making processes to maintain patient safety and redu...
NR 565 Pharmacology reviewed exam 2024 
Mechanism of action: Diuretics 
Decrease blood volume, venous pressure, and preload 
 
 
 
Mechanism of action: Thiazide diuretics 
Block Na-Cl channel in kidneys 
Decreased Na > decreased Na-K+ pump = increased urine output 
 
 
 
Thiazide diuretics consid...
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Mechanism of action: Diuretics 
Decrease blood volume, venous pressure, and preload 
 
 
 
Mechanism of action: Thiazide diuretics 
Block Na-Cl channel in kidneys 
Decreased Na > decreased Na-K+ pump = increased urine output 
 
 
 
Thiazide diuretics consid...
NR 565 Pharm reviewed exam 2024 
CYP3A4 
Decreases elimination 
Increase toxicity of Amio 
 
 
 
Schedule I 
no accepted medical use in the US it may not be prescribed. 
heroin,various opium derivatives,hallucinogenic substances 
 
 
 
Schedule II 
No refills, no telephone orders 
Narcotics, Stimula...
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CYP3A4 
Decreases elimination 
Increase toxicity of Amio 
 
 
 
Schedule I 
no accepted medical use in the US it may not be prescribed. 
heroin,various opium derivatives,hallucinogenic substances 
 
 
 
Schedule II 
No refills, no telephone orders 
Narcotics, Stimula...
NR565 Pharmacology comprehensive final exam 2024 
Severe hypothyroidism 
Myxedema 
 
 
 
Hypothyroid Treatment 
Levothyroxine is the drug of choice for most patients who require thyroid hormone replacement. 
 
 
 
Levothyroxine (Synthroid) Therapeutic Goal 
Resolution of signs and symptoms of hypoth...
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Severe hypothyroidism 
Myxedema 
 
 
 
Hypothyroid Treatment 
Levothyroxine is the drug of choice for most patients who require thyroid hormone replacement. 
 
 
 
Levothyroxine (Synthroid) Therapeutic Goal 
Resolution of signs and symptoms of hypoth...
NR 565 Pharmacology introduction exam 2024. 
Pharmacokinetics 
The study of drug absorption, distribution, metabolism, and excretion in the body 
"What the body does to the drug" 
 
 
 
Factors that affect drug absorption (5) 
Rate of dissolution 
Surface area 
Blood flow 
Lipid solubility 
PH par...
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Pharmacokinetics 
The study of drug absorption, distribution, metabolism, and excretion in the body 
"What the body does to the drug" 
 
 
 
Factors that affect drug absorption (5) 
Rate of dissolution 
Surface area 
Blood flow 
Lipid solubility 
PH par...
NR 565 comprehensive exam 2024(questions & answers) 
hyperthyroidism labs 
decreased TSH and increased T3 &T4 
 
 
 
When to recheck labs after starting levothyroxine? 
6-8 weeks or after dose change, then 12 months once stabilized 
 
 
 
S/S hypothyroidism 
pale, puffy, and expressionless face, col...
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hyperthyroidism labs 
decreased TSH and increased T3 &T4 
 
 
 
When to recheck labs after starting levothyroxine? 
6-8 weeks or after dose change, then 12 months once stabilized 
 
 
 
S/S hypothyroidism 
pale, puffy, and expressionless face, col...
NR 565 Final Exam Study Guide 2024 
eatment of thyroid storm 
High dose potassium iodide or strong iodine solution to suppress thyroid hormone release, 
methimazole to suppress thyroid hormone synthesis, 
beta blocker to reduce heart rate, sedation cooling glucocorticoids and IV fluids 
 
 
 
Result...
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eatment of thyroid storm 
High dose potassium iodide or strong iodine solution to suppress thyroid hormone release, 
methimazole to suppress thyroid hormone synthesis, 
beta blocker to reduce heart rate, sedation cooling glucocorticoids and IV fluids 
 
 
 
Result...
NR 565 Final exam 2024 
Magnesium based antacids 
Contraindicated in patients with renal failure 
 
 
 
Antidiarrheals Contraindication 
toxic megacolon, especially in those with inflammatory bowel disease 
 
 
 
Bismuth subsalicylate (Pepto bismol): 
Contraindicated in children or teenagers during ...
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Magnesium based antacids 
Contraindicated in patients with renal failure 
 
 
 
Antidiarrheals Contraindication 
toxic megacolon, especially in those with inflammatory bowel disease 
 
 
 
Bismuth subsalicylate (Pepto bismol): 
Contraindicated in children or teenagers during ...
NR 565 Pharmacology final exam study guide 2024 
Drugs used in asthma and COPD 
Bronchodilators, antiinflammatories, and mast cell stabilizers 
 
 
 
What drug types are bronchodilators 
Beta 2 adrenergic agonists 
Anticholinergics/muscarinic antagonists 
Methylxanthines/xanthine derivatives 
Leukot...
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Drugs used in asthma and COPD 
Bronchodilators, antiinflammatories, and mast cell stabilizers 
 
 
 
What drug types are bronchodilators 
Beta 2 adrenergic agonists 
Anticholinergics/muscarinic antagonists 
Methylxanthines/xanthine derivatives 
Leukot...
NR 565 Advanced pharmacology midterm exam guide 2024 
antibiotic resistance 
Drug Resistance: 1) Not knowing if our patient has had a recent use of an antibiotic and 2) Provider overuse of broad-spectrum antibiotics. Overuse comes from not performing susceptibility testing, use of antibiotics in the...
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antibiotic resistance 
Drug Resistance: 1) Not knowing if our patient has had a recent use of an antibiotic and 2) Provider overuse of broad-spectrum antibiotics. Overuse comes from not performing susceptibility testing, use of antibiotics in the...
NR 565 Pharmacology comprehensive examinations 2024RA symptoms 
Pain 
Swelling 
Warmth 
Stiffness 
 
 
 
Characteristics: Osteoarthritis 
Slow onset (years) 
1:1 in men/women 
Age > 50 years at onset 
Affects hands, hips, knees 
Mild or local inflammation 
< 30 min morning joint stiffness 
sym...
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Pain 
Swelling 
Warmth 
Stiffness 
 
 
 
Characteristics: Osteoarthritis 
Slow onset (years) 
1:1 in men/women 
Age > 50 years at onset 
Affects hands, hips, knees 
Mild or local inflammation 
< 30 min morning joint stiffness 
sym...
NR 565 Midterm 2024 
RA Characteristics 
 
Onset 
Affected population 
Location 
Joint stiffness duration 
SxS 
weeks-months 
women>men 
common hands, feet, & wrists 
>60 min in AM 
local & sys. 
 
 
 
OA Characteristics 
 
Onset 
Affected population 
Location 
Joint stiffness duration 
SxS 
y...
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RA Characteristics 
 
Onset 
Affected population 
Location 
Joint stiffness duration 
SxS 
weeks-months 
women>men 
common hands, feet, & wrists 
>60 min in AM 
local & sys. 
 
 
 
OA Characteristics 
 
Onset 
Affected population 
Location 
Joint stiffness duration 
SxS 
y...
NR 565 final exam review 2024 
What active hormones are produced by the thyroid? 
triiodothyronine (T3) and thyroxine (T4, tetraiodothyronine) 
 
 
 
4 steps to synthesis of thyroid hormoness 
1. Uptake 
2. Activation (Oxidation by peroxidase) 
3. Iodination of Tyrosine 
4. Coupling of Iodinated Ty...
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What active hormones are produced by the thyroid? 
triiodothyronine (T3) and thyroxine (T4, tetraiodothyronine) 
 
 
 
4 steps to synthesis of thyroid hormoness 
1. Uptake 
2. Activation (Oxidation by peroxidase) 
3. Iodination of Tyrosine 
4. Coupling of Iodinated Ty...
NR 565 Week 2 Study Questions Chapters 1, 4, 13, 25, 52 
Clinical judgment in prescribing includes: 
Factoring in the cost to the patient of the medication prescribed 
 
 
 
Criteria for choosing an effective drug for a disorder include: 
Consulting nationally recognized guidelines for disease manag...
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Clinical judgment in prescribing includes: 
Factoring in the cost to the patient of the medication prescribed 
 
 
 
Criteria for choosing an effective drug for a disorder include: 
Consulting nationally recognized guidelines for disease manag...
NR565 Advanced Pharmacology Fundamentals 2024 
Factors Affecting Drug Absorption 
Rate of dissolution 
Surface area 
Blood flow 
Lipid solubility 
pH partitioning 
 
 
 
Factors Affecting Drug Distribution 
Blood flow to tissues 
Ability to exit the vascular system 
Blood-brain barrier 
Protein-bind...
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Factors Affecting Drug Absorption 
Rate of dissolution 
Surface area 
Blood flow 
Lipid solubility 
pH partitioning 
 
 
 
Factors Affecting Drug Distribution 
Blood flow to tissues 
Ability to exit the vascular system 
Blood-brain barrier 
Protein-bind...
NR 565 comprehensive examination 2024 
Absorption: 
Absorption is the process whereby a substance entering the body is assimilated by it. For proper pharmacokinetics study, it is necessary to know both the rate and the extent to which the active substance or therapeutic moiety are absorbed. They inc...
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Absorption: 
Absorption is the process whereby a substance entering the body is assimilated by it. For proper pharmacokinetics study, it is necessary to know both the rate and the extent to which the active substance or therapeutic moiety are absorbed. They inc...
NR 565 Week 3 Study Questions Chapter 14 
John has clonidine, a centrally acting adrenergic blocker, prescribed for his hypertension. He should: 
Not miss a dose or stop taking the drug because of potential rebound hypertension 
 
 
 
Clonidine has several off-label uses, including: 
 
1. Alcohol an...
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John has clonidine, a centrally acting adrenergic blocker, prescribed for his hypertension. He should: 
Not miss a dose or stop taking the drug because of potential rebound hypertension 
 
 
 
Clonidine has several off-label uses, including: 
 
1. Alcohol an...
NR 565 comprehensive assessment test 2024 (question & answer) 
Jamie is a 24-year-old female with a urinary tract infection. She is healthy, afebrile, and her only drug allergy is sulfa, which gives her a rash. An appropriate first-line antibiotic choice for her would be: 
 
1. Azithromycin 
 
2. Tr...
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Jamie is a 24-year-old female with a urinary tract infection. She is healthy, afebrile, and her only drug allergy is sulfa, which gives her a rash. An appropriate first-line antibiotic choice for her would be: 
 
1. Azithromycin 
 
2. Tr...
NR 565 Pharmacology Week 7 revision guide 2024 
When is GERD defined 
If heartburn/acid reflux symptoms interfere with daily life or occur more than 2x/week 
 
 
 
Defensive factors to protect against ulcers: Mucus 
Secreted by GI mucosa cells, forms protective barrier against acid and pepsin 
 
 
 ...
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When is GERD defined 
If heartburn/acid reflux symptoms interfere with daily life or occur more than 2x/week 
 
 
 
Defensive factors to protect against ulcers: Mucus 
Secreted by GI mucosa cells, forms protective barrier against acid and pepsin 
 
 
 ...
NR565 MIDTERM 2024 STUDY GUIDE 
benefits of full practice authority 
APRNs possess full prescriptive authority depends on their legal right to prescribe without a supervisory or collaborative requirement 
 
 
 
promoting positive outcomes through prudent prescribing practices 
Education provides an...
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benefits of full practice authority 
APRNs possess full prescriptive authority depends on their legal right to prescribe without a supervisory or collaborative requirement 
 
 
 
promoting positive outcomes through prudent prescribing practices 
Education provides an...
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