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BMTCN EXAMS COMPILATION BUNDLE|ALL GRADED A+|GUARANTEED SUCCESS
BMTCN EXAMS COMPILATION BUNDLE|ALL GRADED A+|GUARANTEED SUCCESS
[Show more]BMTCN EXAMS COMPILATION BUNDLE|ALL GRADED A+|GUARANTEED SUCCESS
[Show more]Which of the following medications should a patient taking cyclosporine avoid following an allogenic HSCT? 
A. Torsemide 
B. Bumetanide 
C. Spironolactone 
D. Furosemide 
C. Patients taking cyclosporine should avoid potassium sparing diuretics such as spironolactone. 
 
 
 
How is bronchiolitis obli...
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Add to cartWhich of the following medications should a patient taking cyclosporine avoid following an allogenic HSCT? 
A. Torsemide 
B. Bumetanide 
C. Spironolactone 
D. Furosemide 
C. Patients taking cyclosporine should avoid potassium sparing diuretics such as spironolactone. 
 
 
 
How is bronchiolitis obli...
erythrocyte, platelets, neutrophil, basophil, eosinophil, monoblast, macrophage, monocyte 
Myeloid 
 
 
 
pre- B cell, pre-t cell, plasma cell, natural killer cell, t lymphocyte 
lymphoid 
 
 
 
occurs naturally- phagocytes release inflammatory mediators 
innate immunity 
 
 
 
response of either b ...
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Add to carterythrocyte, platelets, neutrophil, basophil, eosinophil, monoblast, macrophage, monocyte 
Myeloid 
 
 
 
pre- B cell, pre-t cell, plasma cell, natural killer cell, t lymphocyte 
lymphoid 
 
 
 
occurs naturally- phagocytes release inflammatory mediators 
innate immunity 
 
 
 
response of either b ...
When a patient senses a leaking in IV site during a chemotherapy infusion, what does the nurse do first? 
A. Place warning signs across the area to alert others to the spill 
B. Restart the chemotherapy with a new order 
C. Put on the right safety gear 
D. Environmental programs should be contacted ...
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Add to cartWhen a patient senses a leaking in IV site during a chemotherapy infusion, what does the nurse do first? 
A. Place warning signs across the area to alert others to the spill 
B. Restart the chemotherapy with a new order 
C. Put on the right safety gear 
D. Environmental programs should be contacted ...
BMTCN REVIEW QUESTIONS WITH 100% CORRECT ANSWERS 2023
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Add to cartBMTCN REVIEW QUESTIONS WITH 100% CORRECT ANSWERS 2023
What type of transplants commonly have PTLD as a secondary malignancy? 
Allo HSCT with T-cell depleted graft 
 
 
 
Therapies associated with therapy-related acute leukemia and MDS 
alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , radiation, topoisomerase II inhibitors (eg. do...
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Add to cartWhat type of transplants commonly have PTLD as a secondary malignancy? 
Allo HSCT with T-cell depleted graft 
 
 
 
Therapies associated with therapy-related acute leukemia and MDS 
alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , radiation, topoisomerase II inhibitors (eg. do...
Which of the following studies should be completed at regular intervals for a patient receiving long-term steroids? 
 
A. Positron emission tomography scan 
B. Magnetic resonance imaging 
C. Dual energy x-ray absorptiometry 
D. Computed tomography scan 
C. Dual energy x-ray absorptiometry 
 
 
 
The...
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Add to cartWhich of the following studies should be completed at regular intervals for a patient receiving long-term steroids? 
 
A. Positron emission tomography scan 
B. Magnetic resonance imaging 
C. Dual energy x-ray absorptiometry 
D. Computed tomography scan 
C. Dual energy x-ray absorptiometry 
 
 
 
The...
Transplant-related toxicity is a barrier that contributes to the under utilization for which of the following diseases? 
 
A. Non-Hodgkin lymphoma 
B. Acute myeloid leukemia 
C. Sickle cell disease 
D. Neuroblastoma 
C. Sickle cell disease 
 
Despite success of HSCT in sickle cell disease, barriers ...
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Add to cartTransplant-related toxicity is a barrier that contributes to the under utilization for which of the following diseases? 
 
A. Non-Hodgkin lymphoma 
B. Acute myeloid leukemia 
C. Sickle cell disease 
D. Neuroblastoma 
C. Sickle cell disease 
 
Despite success of HSCT in sickle cell disease, barriers ...
Types of SCT (3) 
-Allogeneic 
-Syngeneic 
-Autologous 
 
 
 
Stem Cell Sources (3) 
-Peripheral Blood (PBSCT) 
-Bone Marrow 
-Umbilical Cord (UCB) 
 
 
 
Specific Types of Allogeneic Transplant (6) 
-Syngeneic 
-Matched sibling/related 
-Mismatch related 
-Matched unrelated 
-Mismatched unrelated 
...
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Add to cartTypes of SCT (3) 
-Allogeneic 
-Syngeneic 
-Autologous 
 
 
 
Stem Cell Sources (3) 
-Peripheral Blood (PBSCT) 
-Bone Marrow 
-Umbilical Cord (UCB) 
 
 
 
Specific Types of Allogeneic Transplant (6) 
-Syngeneic 
-Matched sibling/related 
-Mismatch related 
-Matched unrelated 
-Mismatched unrelated 
...
The administration of Epstein-Barr virus (EBV) cytotoxic T-lymphocytes has been found to be a feasible therapeutic option in which EBV mediated-disease process? 
 
a) Lymphoproliferative disease 
b) Neuroblastoma 
c) Nasopharyngeal rhabdomyosarcoma 
d) Acute lymphocytic leukemia 
A) Lymphoproliferat...
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Add to cartThe administration of Epstein-Barr virus (EBV) cytotoxic T-lymphocytes has been found to be a feasible therapeutic option in which EBV mediated-disease process? 
 
a) Lymphoproliferative disease 
b) Neuroblastoma 
c) Nasopharyngeal rhabdomyosarcoma 
d) Acute lymphocytic leukemia 
A) Lymphoproliferat...
T.R. is a 28-year-old woman with acute myeloid leukemia in her second complete remission who is admitted for a matched unrelated allogeneic stem cell transplantation. Her conditioning regimen is as follows: 
 
Myeloablation (busulfan/cyclophosphamide) and immunosuppression with tacrolimus and methot...
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Add to cartT.R. is a 28-year-old woman with acute myeloid leukemia in her second complete remission who is admitted for a matched unrelated allogeneic stem cell transplantation. Her conditioning regimen is as follows: 
 
Myeloablation (busulfan/cyclophosphamide) and immunosuppression with tacrolimus and methot...
Immunoglobulins are secreted by which type of cell? 
 
A. B-lymphocyte 
B. Megakaryocyte 
C. T-lymphocyte 
D. Natural killer 
A. B-lymphocyte 
 
B lymphocytes synthesize and secrete immunoglobulins. 
 
 
 
Which portion of the immunoglobulin activates the complement pathway? 
 
A. MHC Class I 
B. Fa...
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Add to cartImmunoglobulins are secreted by which type of cell? 
 
A. B-lymphocyte 
B. Megakaryocyte 
C. T-lymphocyte 
D. Natural killer 
A. B-lymphocyte 
 
B lymphocytes synthesize and secrete immunoglobulins. 
 
 
 
Which portion of the immunoglobulin activates the complement pathway? 
 
A. MHC Class I 
B. Fa...
Patients who have received an HSCT should receive which of the following annual immunizations? 
A. Yellow Fever 
B. Intranasal influenza 
C. Inactive influenza 
D. Live rotavirus 
C. Inactive influenza is recommended yearly. 
 
 
 
What is an advantage of using umbilical cord blood for an HSCT? 
A. ...
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Add to cartPatients who have received an HSCT should receive which of the following annual immunizations? 
A. Yellow Fever 
B. Intranasal influenza 
C. Inactive influenza 
D. Live rotavirus 
C. Inactive influenza is recommended yearly. 
 
 
 
What is an advantage of using umbilical cord blood for an HSCT? 
A. ...
Two days following a near-drowning accident, a pt is dyspneic, using accessory muscles, expectorating large amounts of secretions and reporting feeling of impending death. Changes to the assessment data include 
RR- 24 TO 36 
CXR clear to bilateral diffuse infiltrates 
ABG 40% face mask or 100% non-...
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Add to cartTwo days following a near-drowning accident, a pt is dyspneic, using accessory muscles, expectorating large amounts of secretions and reporting feeling of impending death. Changes to the assessment data include 
RR- 24 TO 36 
CXR clear to bilateral diffuse infiltrates 
ABG 40% face mask or 100% non-...
What is the most important rationale for giving total body irradiation in multiple fractions? 
A. It is easier for patients. 
B. It decreases short-term side effects. 
C. It decreases long-term side effects. 
D. It is easier for radiation staff. 
C. It decreases long-term side effects. 
 
 
 
What c...
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Add to cartWhat is the most important rationale for giving total body irradiation in multiple fractions? 
A. It is easier for patients. 
B. It decreases short-term side effects. 
C. It decreases long-term side effects. 
D. It is easier for radiation staff. 
C. It decreases long-term side effects. 
 
 
 
What c...
If the activated T-lymphocytes either directly/indirectly produce and amplify tissue damage within the target organs, which of the following phases of pathophysiology of Graft-Versus-Host Disease would it be considered? 
 
a.) phase 1 
b) phase 2 
c) phase 3 
d) phase 4 
Answer: Phase 3 
 
There are...
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Add to cartIf the activated T-lymphocytes either directly/indirectly produce and amplify tissue damage within the target organs, which of the following phases of pathophysiology of Graft-Versus-Host Disease would it be considered? 
 
a.) phase 1 
b) phase 2 
c) phase 3 
d) phase 4 
Answer: Phase 3 
 
There are...
Nursing Practice 
Influenced by: 
 
Professional organizations (ANA, ONS) 
-Scope and standards of practice 
 
State boards of nursing 
 
Accreditation agencies 
-The Joint Commission (TJC) 
-Foundation for the Accreditation of Cellular Therapy (FACT) 
 
Ethical and legal issues 
 
Self-care 
 
 
 
...
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Add to cartNursing Practice 
Influenced by: 
 
Professional organizations (ANA, ONS) 
-Scope and standards of practice 
 
State boards of nursing 
 
Accreditation agencies 
-The Joint Commission (TJC) 
-Foundation for the Accreditation of Cellular Therapy (FACT) 
 
Ethical and legal issues 
 
Self-care 
 
 
 
...
What is a patient who received a T-cell-depleted transplant at risk for developing within the first year following transplant? 
 
A. Acute myeloid leukemia 
B. Breast cancer 
C. Basal cell carcinoma 
D. Post-transplant lymphoproliferative disorders 
D. Post-transplant lymphoproliferative disorders 
...
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Add to cartWhat is a patient who received a T-cell-depleted transplant at risk for developing within the first year following transplant? 
 
A. Acute myeloid leukemia 
B. Breast cancer 
C. Basal cell carcinoma 
D. Post-transplant lymphoproliferative disorders 
D. Post-transplant lymphoproliferative disorders 
...
Which of the following studies should be completed at regular intervals for a patient receiving long-term steroids? 
 
A. Positron emission tomography scan 
B. Magnetic resonance imaging 
C. Dual energy x-ray absorptiometry 
D. Computed tomography scan 
C. Dual energy x-ray absorptiometry 
 
 
 
The...
Preview 4 out of 31 pages
Add to cartWhich of the following studies should be completed at regular intervals for a patient receiving long-term steroids? 
 
A. Positron emission tomography scan 
B. Magnetic resonance imaging 
C. Dual energy x-ray absorptiometry 
D. Computed tomography scan 
C. Dual energy x-ray absorptiometry 
 
 
 
The...
TRANSPLANT PREP REGIMENS 
Treatment leading up to transplant 
 
 
 
Acronyms: 
Ara-C 
BCNU 
BU 
Cy 
DLT 
SCT 
TBI 
Cytarabine 
Carmustine 
Busulfan 
Cyclophosphamide 
Dose limiting toxicity 
DStem cell transplant 
Total body irradiation 
 
 
 
Induction chemotherapy 
The first treatment given for a ...
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Add to cartTRANSPLANT PREP REGIMENS 
Treatment leading up to transplant 
 
 
 
Acronyms: 
Ara-C 
BCNU 
BU 
Cy 
DLT 
SCT 
TBI 
Cytarabine 
Carmustine 
Busulfan 
Cyclophosphamide 
Dose limiting toxicity 
DStem cell transplant 
Total body irradiation 
 
 
 
Induction chemotherapy 
The first treatment given for a ...
3 types of Transplants 
-Autologous 
-Allogeneic 
-Syngeneic 
 
 
 
3 Sources of Stem Cells 
-Peripheral Blood 
-Bone Marrow 
-Umbilical Cord Blood 
 
 
 
Autologous 
-removing stem cells from the pt with the intent to reinfuse the cells at a later date 
-before they are able to have their stem cell...
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Add to cart3 types of Transplants 
-Autologous 
-Allogeneic 
-Syngeneic 
 
 
 
3 Sources of Stem Cells 
-Peripheral Blood 
-Bone Marrow 
-Umbilical Cord Blood 
 
 
 
Autologous 
-removing stem cells from the pt with the intent to reinfuse the cells at a later date 
-before they are able to have their stem cell...
FACT 
The Foundation for the Accreditation of Cellular Therapy 
-FACT was formed in an effort to help standardize and improve the quality of the transplant process. 
-FACT requires a battery of tests for the potential SCT recipient to ensure adequate organ function and screening for certain diseases...
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Add to cartFACT 
The Foundation for the Accreditation of Cellular Therapy 
-FACT was formed in an effort to help standardize and improve the quality of the transplant process. 
-FACT requires a battery of tests for the potential SCT recipient to ensure adequate organ function and screening for certain diseases...
BMTCN REVIEW CHAPTER 7 - SURVIVORSHIP ISSUES WITH COMPLETE SOLUTIONS
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Add to cartBMTCN REVIEW CHAPTER 7 - SURVIVORSHIP ISSUES WITH COMPLETE SOLUTIONS
BMTCN CHAPTER 8 PROFESSIONAL PRACTICE WITH COMPLETE SOLUTIONS 2023.
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Add to cartBMTCN CHAPTER 8 PROFESSIONAL PRACTICE WITH COMPLETE SOLUTIONS 2023.
BMTCN CHAPTER 3 - PRETRANSPLANT ISSUES WITH 100% CORRECT ANSWERS.
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Add to cartBMTCN CHAPTER 3 - PRETRANSPLANT ISSUES WITH 100% CORRECT ANSWERS.
M.J. is to undergo an autologous transplant. From whom will he receive his stem cells? 
A. A matched related donor 
B. A matched unrelated donor 
C. An umbilical cord blood donor 
D. Himself 
D. Himself 
 
 
 
P.F. has undergone an allogeneic transplant using umbilical cord blood as the stem cell so...
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Add to cartM.J. is to undergo an autologous transplant. From whom will he receive his stem cells? 
A. A matched related donor 
B. A matched unrelated donor 
C. An umbilical cord blood donor 
D. Himself 
D. Himself 
 
 
 
P.F. has undergone an allogeneic transplant using umbilical cord blood as the stem cell so...
M.J. is to undergo an autologous transplant. From whom will he receive his stem cells? 
A. A matched related donor 
B. A matched unrelated donor 
C. An umbilical cord blood donor 
D. Himself 
D. Himself 
 
 
 
P.F. has undergone an allogeneic transplant using umbilical cord blood as the stem cell so...
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Add to cartM.J. is to undergo an autologous transplant. From whom will he receive his stem cells? 
A. A matched related donor 
B. A matched unrelated donor 
C. An umbilical cord blood donor 
D. Himself 
D. Himself 
 
 
 
P.F. has undergone an allogeneic transplant using umbilical cord blood as the stem cell so...
Of the following, which processes would be considered involved with the human innate immunity? 
 
Skin (physical barrier) 
Acute-phase protein production 
Sneezing (mechanical barriers) 
All of the above 
All of the above 
 
 
 
If the activated T-lymphocytes either directly/indirectly produce and a...
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Add to cartOf the following, which processes would be considered involved with the human innate immunity? 
 
Skin (physical barrier) 
Acute-phase protein production 
Sneezing (mechanical barriers) 
All of the above 
All of the above 
 
 
 
If the activated T-lymphocytes either directly/indirectly produce and a...
What are the types of cardiac diseases common post HSCT? What conditioning medications can cause these diseases? 
Cardiomyopathy, arrhythmias, congestive heart failure - high dose cytoxan and radiation causes this 
 
HTN/Dislipidemia: Immunosuppression meds 
 
HTN/Hyperkalemia: Cyclosporine 
 
HTN/H...
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Add to cartWhat are the types of cardiac diseases common post HSCT? What conditioning medications can cause these diseases? 
Cardiomyopathy, arrhythmias, congestive heart failure - high dose cytoxan and radiation causes this 
 
HTN/Dislipidemia: Immunosuppression meds 
 
HTN/Hyperkalemia: Cyclosporine 
 
HTN/H...
Leukapheresis 
- Peripheral blood stem cell collection: goal # cells in adults vs. pediatrics, how much blood commonly processed 
- Bone marrow: goal # cells, how much marrow obtained 
PBSCs: 5 x10^6 CD34+ cells per kg of recipient's body weight 
- Adults: 12-15L of blood commonly processed 
- Pedi...
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Add to cartLeukapheresis 
- Peripheral blood stem cell collection: goal # cells in adults vs. pediatrics, how much blood commonly processed 
- Bone marrow: goal # cells, how much marrow obtained 
PBSCs: 5 x10^6 CD34+ cells per kg of recipient's body weight 
- Adults: 12-15L of blood commonly processed 
- Pedi...
CXCR4 
Regulates trafficking and homing of stem cells 
 
Expressed on surface of HSCs 
 
 
 
1st stem cell transplant 
1960's, infant with immunodeficiency disorder, matched sib 
 
 
 
SDF-1 
Secreted by bone marrow stromal cells 
 
Involved in retaining HSCs within bone marrow as well as releasing...
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Add to cartCXCR4 
Regulates trafficking and homing of stem cells 
 
Expressed on surface of HSCs 
 
 
 
1st stem cell transplant 
1960's, infant with immunodeficiency disorder, matched sib 
 
 
 
SDF-1 
Secreted by bone marrow stromal cells 
 
Involved in retaining HSCs within bone marrow as well as releasing...
What statement(s) is true regarding the Pre-Review Questionnaire (PRQ)? 
Once the site visit has taken place, the PRQ closes permanently. 
 
 
 
Which of the following represent(s) prospective case types typically presented at a multidisciplinary cancer case conference? 
Previously diagnosed, initia...
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Add to cartWhat statement(s) is true regarding the Pre-Review Questionnaire (PRQ)? 
Once the site visit has taken place, the PRQ closes permanently. 
 
 
 
Which of the following represent(s) prospective case types typically presented at a multidisciplinary cancer case conference? 
Previously diagnosed, initia...
pre-transplant workup/evaluation 
-labs: CBC+diff, chems, hep B&C, HIV, human t cell leukemia virus type 1, CMV, HSV, VZV, pregnancy, ABO/RH-, HLA, serology, rapid plasma reagin testing 
-organ function tests: EF>50%, echo, EKG 
-disease eval: BMBx, LP, CT, MRI, bone scans/survey, tumor markers, ...
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Add to cartpre-transplant workup/evaluation 
-labs: CBC+diff, chems, hep B&C, HIV, human t cell leukemia virus type 1, CMV, HSV, VZV, pregnancy, ABO/RH-, HLA, serology, rapid plasma reagin testing 
-organ function tests: EF>50%, echo, EKG 
-disease eval: BMBx, LP, CT, MRI, bone scans/survey, tumor markers, ...
What is graft vs host disease? 
Donor T cells recognize antigens on cells in the recipients organs as foreign and mount an immunologic repsonse 
 
 
 
What are the two categories of GVHD? What determines the category? 
Acute and chronic. Clinical manifestations categorize GVHD 
 
 
 
What does acute...
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Add to cartWhat is graft vs host disease? 
Donor T cells recognize antigens on cells in the recipients organs as foreign and mount an immunologic repsonse 
 
 
 
What are the two categories of GVHD? What determines the category? 
Acute and chronic. Clinical manifestations categorize GVHD 
 
 
 
What does acute...
Goal of Transplant 
-Cure disease 
-Increase disease free survival 
 
 
 
Hematopoiesis 
-Regulation, production and development of blood cells 
-Pluripotent Stem cells 
-Progenitor Stem Cells. 
-Myeloid and lymphoid lineage 
 
 
 
Myeloid progenitor cells mature into: 
Megakaryocytes (platelets) 
E...
Preview 1 out of 3 pages
Add to cartGoal of Transplant 
-Cure disease 
-Increase disease free survival 
 
 
 
Hematopoiesis 
-Regulation, production and development of blood cells 
-Pluripotent Stem cells 
-Progenitor Stem Cells. 
-Myeloid and lymphoid lineage 
 
 
 
Myeloid progenitor cells mature into: 
Megakaryocytes (platelets) 
E...
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