UNE BIOCHEMISTRY TESTS COMPILATION BUNDLE

A 19-year-old boy is diagnosed with Creutzfeldt-Jakob disease which is caused by the introduction of an amyloid fold in the disease-causing protein. The introduction of this fold causes the protein to transition from a primarily alpha helical structure to an aggregate of mostly beta sheets. This cha...

Under low energy conditions, AMP will bind to phosphofructokinase I and glycogen phosphorylase at site unique to the active site. This enhances the activity of these enzymes. This is an example of which of the follow types of enzyme regulation? correct answer: Allosteric activation An example of...

primary structure of protein correct answer: linear sequence of amino acids in the polypeptide chain secondary structure of protein correct answer: alpha helix and beta pleated sheet alpha helix correct answer: formed when the carbonyl group of peptide bond forms a hydrogen bond with the am...

Succinate is a substrate for which complex in the electron transport chain? a.) Complex 1 (NADH-1 oxidoreductase) b.) Complex IV (Cyt c oxidase) c.) Complex V (ATP synthase) d.) complex II (Succinate-Q reductase) correct answer: Complex II (succinate-Q reductase) (D) Which of the fol...

The glucose-alanine cycle is a method of transferring ammonia from the skeletal muscle to the liver. In this process the non-toxic carrier of ammonia is which of the following compounds? correct answer: Alanine Which of the following enzymes is correctly paired with its activator? correct answer...

An individual goes to bed around 8 pm and doesn't wake up until 9 am the next morning. During this time, which of the following is the primary oxidizable substrate in the skeletal muscle? correct answer: Free fatty acids Under fasted conditions as described above, the skeletal muscle and liver ...

Somatostatin reduces the secretion of both glucagon and insulin through which of the following mechanisms? a. Somatostatin activates an activator G-protein b. Somatostatin activates MAPK cascade c. Somatostatin activates an inhibitory G-protein d. Somatostatin uses Ca+2 as a downstream signal...

Under fasting conditions (ratio of insulin: glucagon <1), elevated glucagon will activate which of the following enzymes? correct answer: hormone sensitive lipase Ketonuria, hypoglycemia, and severe acidosis are prime diagnostic indicators of the presentation of type 1 diabetic ketoacidosis. ...

Malate can be converted to pyruvate in the cytosol. Which of the following compounds is directly generated in this conversion and is essential for fatty acid synthesis? FADH2 ATP Acetyl-CoA NADPH correct answer: NADPH An increase in the ratio of insulin to glucagon will increase the ...

A 3-year-old male is brought to the emergency department by his parents. He is unconscious on admittance and his blood glucose was 15 mg/dl, ( normal 75 - 105 mg/dl). Further testing showed this individual had a deficiency in carnitine. Based on this diagnosis you would also expect which of the foll...

What are the main products of beta oxidation? correct answer: 1 NADH, 1 FADH, 1 Acetyl CoA So in the case of an 11-year-old girl brought to the emergency department by her father, he's reporting that she's been very thirsty and needing to make frequent strips to the bathroom. Today, she report...

What are the direct products of Beta Oxidation? correct answer: NADH FADH2 Acetyl CoA What does Acetyl CoA get used for correct answer: ketogenesis allosterically activates Pyruvate Carboxylase An 11yo girl is brought into the emergency department by her father. He reports that she has re...

UNE BioChem Unit 4 Final EXAM| 101 Questions| With Complete Solutions

The cellular uptake of LDL increase intracellular cholesterol levels. This has which of the following impacts on de novo cholesterol synthesis? correct answer: Increases degradation of HMG-CoA reductase Dietary cholesterol is primarily transported in the body by which of the following lipoprotei...

Control of Fatty Acid Synthesis vs. Oxidation correct answer: When Insulin is HIGH --> fatty acid synthesis occurs When Glucagon is HIGH --> lipolysis, fatty acid B-oxidation, ketogenesis occur **These never happen at the same time! Lipolysis correct answer: Process of releasing free ...

If unregulated, which of the following pairs of enzymes would represent a futile cycle? correct answer: Fructose-1,6-bisphosphatase and phosphofructokinase 1 Ethanol metabolism correct answer: Increases the ratio of NADH/NAD+ The first step in ethanol metabolism is in the cytosol and generat...

In the liver, which of the following key inhibitory events ensures that newly synthesized palmitoyl-CoA is not immediately oxidized? Carnitine palmitoyl transferase-I (CPTI) by palmitoylcarnitine Carnitine palmitoyl transferase-II (CPTII) by acetyl-CoA Acyl-CoA synthetase by malonyl CoA ...

Under fasting conditions (ratio of insulin to glucagon <1), elevated glucagon will activate which of the following enzymes? correct answer: Hormone sensitive lipase The process of ketogenesis refers to the conversion of acetyl CoA to which of the following compounds? correct answer: D-3-hydr...

An 11-year-old girl is brought to the emergency department by her father. He reports she has recently been very thirsty and needing to make frequent trips to the bathroom. At her soccer game today, she complained of lightheadedness and that the symptoms did not resolve even after drinking a power be...

Which of the following urea cycle enzymes catalyzes the reaction hydrolyzing the release of urea from arginine? correct answer: Arginase Arginase releases urea from arginine through a hydrolytic cleavage. Which of the following enzymes is likely to be active in both the fed and fasted states...

UNE CHEM 1005: MEDICAL BIOCHEMISTRY FINAL EXAM QUESTIONS WITH COMPLETE SOLUTIONS