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ASCP Hematology BUNDLED exams 2023 with 100% correct answers
ASCP Hematology exam 2023 with 100% correct answers ASCP Hematology Exam-MLT 2023 with 100% correct answers
[Show more]ASCP Hematology exam 2023 with 100% correct answers ASCP Hematology Exam-MLT 2023 with 100% correct answers
[Show more]Name the locations of active marrow in adults: 
sternum, skull, ribs, pelvis, vertebrae 
 
 
 
Where does hematopoiesis take place during the first 2 months of gestation? 
yolk sac 
 
 
 
Where does the majority of hematopoiesis take place during the 2nd through 7th month of gestation? 
spleen 
 
 
...
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Add to cartName the locations of active marrow in adults: 
sternum, skull, ribs, pelvis, vertebrae 
 
 
 
Where does hematopoiesis take place during the first 2 months of gestation? 
yolk sac 
 
 
 
Where does the majority of hematopoiesis take place during the 2nd through 7th month of gestation? 
spleen 
 
 
...
____________ and ____________ are required for heme synthesis 
iron and protoporphyrin 
 
 
 
Fe Transport protein 
Transferrin 
 
 
 
Major Fe storage form 
Ferritin 
 
 
 
H2O insoluble Fe storage form (long-term) 
Hemosiderin 
 
 
 
Excess iron that is stored in tissues and body organs can lead t...
Preview 2 out of 7 pages
Add to cart____________ and ____________ are required for heme synthesis 
iron and protoporphyrin 
 
 
 
Fe Transport protein 
Transferrin 
 
 
 
Major Fe storage form 
Ferritin 
 
 
 
H2O insoluble Fe storage form (long-term) 
Hemosiderin 
 
 
 
Excess iron that is stored in tissues and body organs can lead t...
The light-colored zone adjacent to the nucleus in a plasmacyte is the: 
 
A. ribosome 
B. chormatin 
C. mitochondira 
D. Golgi area 
D. Golgi area 
 
 
 
The majority of the iron in an adult is found as a constituent of: 
 
A. hemoglobin 
B. hemosiderin 
C. myglobin 
D. transferrin 
A. hemoglobin 
 ...
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Add to cartThe light-colored zone adjacent to the nucleus in a plasmacyte is the: 
 
A. ribosome 
B. chormatin 
C. mitochondira 
D. Golgi area 
D. Golgi area 
 
 
 
The majority of the iron in an adult is found as a constituent of: 
 
A. hemoglobin 
B. hemosiderin 
C. myglobin 
D. transferrin 
A. hemoglobin 
 ...
Acanthocytes may be associated with: 
Severe liver disease. 
Splenectomy. 
Malabsorption. 
Hypothyroidism. 
Vitamin E deficiency. 
Abetalipoproteinemia. 
 
 
 
Schistocytes may be associated with: 
Hemolytic uremic syndrome. 
Thrombotic thrombocytopenia purpura. 
Disseminated intravascular coagulati...
Preview 2 out of 5 pages
Add to cartAcanthocytes may be associated with: 
Severe liver disease. 
Splenectomy. 
Malabsorption. 
Hypothyroidism. 
Vitamin E deficiency. 
Abetalipoproteinemia. 
 
 
 
Schistocytes may be associated with: 
Hemolytic uremic syndrome. 
Thrombotic thrombocytopenia purpura. 
Disseminated intravascular coagulati...
The light-colored zone adjacent to the nucleus in a plasmacyte is the: 
 
A. ribosome 
B. chromatin 
C. mitochondria 
D. Golgi area 
D. Golgi area 
 
 
 
The majority of the iron in an adult is found as a constituent of: 
 
A. hemoglobin 
B. hemosiderin 
C. myoglobin 
D. transferrin 
A. hemoglobin 
...
Preview 3 out of 18 pages
Add to cartThe light-colored zone adjacent to the nucleus in a plasmacyte is the: 
 
A. ribosome 
B. chromatin 
C. mitochondria 
D. Golgi area 
D. Golgi area 
 
 
 
The majority of the iron in an adult is found as a constituent of: 
 
A. hemoglobin 
B. hemosiderin 
C. myoglobin 
D. transferrin 
A. hemoglobin 
...
Dohle bodies 
Light blue patches in cytoplasm of neutrophils. Infection, burns 
 
 
 
Erythrocytes 
O2 transport. Produced in BM 
 
 
 
Mean Corpuscular Hemoglobin (MCH) formula 
(HGBx10)/RBC 
 
 
 
Mean Corpuscular Hemoglobin Concentration (MCHC) formulao 
(HGBx100)/HCT 
 
 
 
Granulocytes 
Defense...
Preview 3 out of 23 pages
Add to cartDohle bodies 
Light blue patches in cytoplasm of neutrophils. Infection, burns 
 
 
 
Erythrocytes 
O2 transport. Produced in BM 
 
 
 
Mean Corpuscular Hemoglobin (MCH) formula 
(HGBx10)/RBC 
 
 
 
Mean Corpuscular Hemoglobin Concentration (MCHC) formulao 
(HGBx100)/HCT 
 
 
 
Granulocytes 
Defense...
The majority of the iron in an adult is found as a constituent of 
hemoglobin 
 
 
 
In order for hemoglobin to combine reversibly with oxygen, the iron must 
In the ferrous state 
 
 
 
Which description best fits the Donath-Landsteiner antibody 
IgG biphasic hemolysin 
 
 
 
Spherocytes are a defi...
Preview 2 out of 12 pages
Add to cartThe majority of the iron in an adult is found as a constituent of 
hemoglobin 
 
 
 
In order for hemoglobin to combine reversibly with oxygen, the iron must 
In the ferrous state 
 
 
 
Which description best fits the Donath-Landsteiner antibody 
IgG biphasic hemolysin 
 
 
 
Spherocytes are a defi...
Insufficient centrifugation will result in: 
 
A. A false increase in hematocrit (Hct) value 
B. A false decrease in Hct value 
C. No effect on Hct value 
D. All of these options, depending on the patient 
A. Insufficient centrifugation does not pack down the 
red blood cells; therefore, the Hct, wh...
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Add to cartInsufficient centrifugation will result in: 
 
A. A false increase in hematocrit (Hct) value 
B. A false decrease in Hct value 
C. No effect on Hct value 
D. All of these options, depending on the patient 
A. Insufficient centrifugation does not pack down the 
red blood cells; therefore, the Hct, wh...
Bone marrow and Peripheral blood 
Growth factors that stimulate cell line maturation are: 
 
 
 
Locations of active marrow in adults 
Flat bones 
 
 
 
What conditions are associated with increased storage of iron 
Hemosiderosis 
Hemochromatosis 
 
 
 
Transferrin 
iron transport protein 
 
 
 
Iro...
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Add to cartBone marrow and Peripheral blood 
Growth factors that stimulate cell line maturation are: 
 
 
 
Locations of active marrow in adults 
Flat bones 
 
 
 
What conditions are associated with increased storage of iron 
Hemosiderosis 
Hemochromatosis 
 
 
 
Transferrin 
iron transport protein 
 
 
 
Iro...
Order of heme synthesis 
Porphobilinogen, Uroporphyrinogen, Coproporphyrinogen, Protoporphyrinogen 
 
 
 
Macrocytic 
The characteristic erythrocyte found in pernicious anemia 
 
 
 
Idiopathic Hemochromatosis 
Results in iron overload in tissues 
 
 
 
Phlebotomy treatment 
Causes iron deficiency d...
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Add to cartOrder of heme synthesis 
Porphobilinogen, Uroporphyrinogen, Coproporphyrinogen, Protoporphyrinogen 
 
 
 
Macrocytic 
The characteristic erythrocyte found in pernicious anemia 
 
 
 
Idiopathic Hemochromatosis 
Results in iron overload in tissues 
 
 
 
Phlebotomy treatment 
Causes iron deficiency d...
hexose monohosphate shunt 
found in the erythrocyte to provide reduced glutathione to prevent oxidation of hemoglobin 
 
 
 
May-hegglin anomaly 
Dohle bodies and giant platelets. Autosomal dominant disorder 
 
 
 
Chediak-Higashi syndrome 
associated w/ cytoplasmic granule fusion 
 
 
 
Shift to th...
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Add to carthexose monohosphate shunt 
found in the erythrocyte to provide reduced glutathione to prevent oxidation of hemoglobin 
 
 
 
May-hegglin anomaly 
Dohle bodies and giant platelets. Autosomal dominant disorder 
 
 
 
Chediak-Higashi syndrome 
associated w/ cytoplasmic granule fusion 
 
 
 
Shift to th...
CMP 
Common Myeloid Progenitor 
-Granulocyte 
-Erythrocyte 
-Monocyte 
-Megakaryocyte 
 
 
 
CLP 
Common Lymphoid Progenitor 
-T-lymphocyte 
-B-lymphocyte 
-NK cell 
 
 
 
Pronormoblast 
14-24 um 
N:C ratio 8:1 
1-3 nucleoli 
Fine chromatin 
 
 
 
Basophilic Normoblast 
12-17 um 
N:C ratio 6:1 
No n...
Preview 3 out of 16 pages
Add to cartCMP 
Common Myeloid Progenitor 
-Granulocyte 
-Erythrocyte 
-Monocyte 
-Megakaryocyte 
 
 
 
CLP 
Common Lymphoid Progenitor 
-T-lymphocyte 
-B-lymphocyte 
-NK cell 
 
 
 
Pronormoblast 
14-24 um 
N:C ratio 8:1 
1-3 nucleoli 
Fine chromatin 
 
 
 
Basophilic Normoblast 
12-17 um 
N:C ratio 6:1 
No n...
Right shift 
Decreased oxygen affinity/increased O2 release 
high 2,3-DPG, increased body temperature, decreased pH 
 
 
 
Left shift 
Increased oxygen affinity 
low 2,3-DPG levels, decreased body temp, increased pH 
 
 
 
Howell-Jolly bodies 
DNA, remnants of nuceli/nuclear fragments, aggregates of...
Preview 2 out of 9 pages
Add to cartRight shift 
Decreased oxygen affinity/increased O2 release 
high 2,3-DPG, increased body temperature, decreased pH 
 
 
 
Left shift 
Increased oxygen affinity 
low 2,3-DPG levels, decreased body temp, increased pH 
 
 
 
Howell-Jolly bodies 
DNA, remnants of nuceli/nuclear fragments, aggregates of...
Paroxysmal Cold Hemoglobinuria (PCH) 
Stem cell mutation in the PIGA gene that causes abnormal differentiated hematopoietic cells to be cloned. These cells bind large amounts of complement, causing hemolysis. 
 
 
 
Spurr Cell Anemia 
Acquired hemolytic anemia due to liver disease in which serum lip...
Preview 2 out of 8 pages
Add to cartParoxysmal Cold Hemoglobinuria (PCH) 
Stem cell mutation in the PIGA gene that causes abnormal differentiated hematopoietic cells to be cloned. These cells bind large amounts of complement, causing hemolysis. 
 
 
 
Spurr Cell Anemia 
Acquired hemolytic anemia due to liver disease in which serum lip...
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