Psci 501 final exam - Study guides, Class notes & Summaries

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PSCI 501 FINAL EXAM Questions With Well Elaboration Answers.
  • PSCI 501 FINAL EXAM Questions With Well Elaboration Answers.

  • Exam (elaborations) • 11 pages • 2024
  • Sotorasib - correct answer • Introduction to disease state: KRAS G12C mutant non-small cell lung cancer • Mechanism of action: Binds to the cysteine residue in KRAS g12C mutation and holds the protein in its inactive form (KRAS inhibitor) • Hit discovery: (must bind to cysteine residue so used Chemotype evolution and used HTS library) • Formulation and/or delivery: Orally Voxelotor (Oxbryta) - correct answer Use for: Sickle cell Disease Mechanism of Acti...
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