Ligand binding - Study guides, Class notes & Summaries

What factors affect binding affinity? Correct Answer-Shape, charge, H-bonding, hydrophobics reversible binding Correct Answer-the association of a protein with its ligan is concentration-dependent K_d Correct Answer-the concentration of ligand at which 1/2 of the protein is ligand-bound K_d = k_d / k_a or k_off / k_on also = k_-1 / k_1 Calculate fraction of protein bound to ligand Correct Answer-[L] / ([L] + K_d) affinity and concentration association Correct Answer-if they bind at...

Phosphatase correct answers This myosin-actin interaction forms the basis of the cross-bridge cycle (CBC), which causes muscle contraction, as in skeletal -bridge cycling (CBC) requires phosphorylation of the myosin light chain (LC20). A .............. is an enzyme that removes a phosphate group from its substrate composed of actin and are dynamic and are lengthen by polymerization or shortened by depolarization correct answers microfilaments are provide strucule support for the cell ...

Week 3 Quiz #1 is C. 1. Volume neurotransmission refers to? The diffusion of neurotransmitter to nearby neurons. 2. Retrograde neurotransmissions refers to? The flow of neurotransmitter from postsynaptic neuron to presynaptic neuron 3. Use the following CYP450 table to hypothesize drug interactions and their clinical significance for a patient on clozapine who carbamazepine, a mood stabilizer? Clozapine levels would decrease, placing the patient at risk for re-emergence of psychotic sym...

nonpolar endocrines IF covers short distances, endocrines travel in plasma What is the only type of ligand utilizing plasma binding protein? no! brings it TO the cell uber brings you to the store, not into it T or F? does plasma binding protein bring message into cell? nonpolar ligand + intracellular receptor = message transcription which pathway increases or decreases transcription? metabolize receptors (intracellular receptor, cannot be done with membrane bound how could we stop m...

It is true that a eukaryotic cell: a. Is smaller than a prokaryotic cell. b. Contains structures called organelles c. Lacks a well-defined nucleus. d. Does not contain histones. - b Eukaryotic cells contain organelles and histones, they have a well-defined nucleus, and are larger than prokaryotic cells. The function of a histone found in a eukaryote cell focuses on cellular: a. division b. movement c. activities d. Deoxyribonucleic acid (DNA) folding - d. The histones are binding pro...

Draw and label the myoglobin binding curve. - Answer A hyperbolic curve -> Y is the fraction of ligand-binding sites -> Kd is the dissociation constant (x value of y = 0.5) -> A high Kd means more dissociation. -> P50 is the partial pressure when oxygen (or something) occupies 50% of the binding sites. What does the hyperbolic shape tell us about the sensitivity of myoglobin to changes in ligand concentration? - Answer Myoglobin is very sensitive to ligand and will take up a lo...

Psychopharmacology Drugs The Brain And Behavior 3rd Edition Meyer Nursing Test Bank Multiple Choice 1. refer(s) to specific molecular changes that occur when a drug binds to a particular target site or receptor, while are the resulting widespread alterationsin function. a. Drug action; therapeutic effects b. Side effects; drug effects c. Therapeutic effects; side effects d. Drug action; drug effects Answer: d Textbook Reference: Pharmacology: The Science of Drug Action 2. After drug administrati...

ATE 2634 Final Exam Questions and Answers Already Passed **1. How is medication typically administered in veterinary medicine?** Options: - Intravenous - Intramuscular - Sublingual - Oral Oral **2. Identify four common injection sites used in veterinary practice.** Options: - Intradermal, subcutaneous, intravenous, epidural - Neck, gluteal region, pectoral region, semimembranosus/semitendinosus - Dorsal lumbar, thoracic, mammary, femoral - Jugular, cephalic, coccygeal, sap...

TEST BANK PATHOPHYSIOLOGY THE BIOLOGICAL BASIS FOR DISEASE IN ADULTS AND CHILDREN BY McCance Chapter 1: Cellular Biology MULTIPLE CHOICE 1. Which statement best describes the cellular function of metabolic absorption? a. Cells can produce proteins. c. Cells can take in and use nutrients. b. Cells can secrete digestive enzymes. d. Cells can synthesize fats. ANS: C In metabolic absorption, all cells take in and use nutrients and other substances from their surroundings. The remaini...

Complete Solutions Manual for Biomolecular Thermodynamics, 1st Edition by Douglas Barrick ; ISBN13: 9781315380193. (Full Chapters included Chapter 1 to 14).... Chapter 1: Probabilities and Statistics in Chemical and Biothermodynamics. Chapter 2: Mathematical Tools in Thermodynamics. Chapter 3: The Framework of Thermodynamics and the First Law. Chapter 4: The Second Law and Entropy. Chapter 5: Free Energy as a Potential for the Laboratory and for Biology. Chapter 6: Using Chemical Potential...