Melphalan - Study guides, Class notes & Summaries

BMTCNCyclophosphamide - correct answer anemia, leukopenia, thrombocytopenia N/V, mucositis/stomatitis, diarrhea hepatotoxicity/HSOS Hemorrhagic cystitis, nephrotoxicity electrolyte imbalances cardiotoxicity, fibrosis pneumonitis infertility alopecia erythema headaches/AMS 2ndary malignancy nasal congestion conjunctivitis Carboplatin - correct answer A/L/T N/V, mucos/stomatitis diarrhea, constipation nephrotoxicity, electrolyte imbalances dermatitis, alopecia hypersensitivity...

CPHON Examples of Alkylating Agents - correct answer Carboplatin, Cisplatin, Carmustine, Lomustine, Cytoxan, Ifosfamide, Melphalan, Temozolomide, Thiotepa Examples of Antimetabolites (Cell-cycle Specific) - correct answer MTX, 5-FU, ARA-C, 6-MP, 6-TG Examples of Plant Detrivatives (Cell-cycle Specific) - correct answer Etoposide, irinotecan, vincristine Examples of Antibiotics for Cancer treatment - correct answer Dactinomycin, Bleomycin Examples of Anthracyclines - correct answer D...

BMTCNCyclophosphamide - correct answer anemia, leukopenia, thrombocytopenia N/V, mucositis/stomatitis, diarrhea hepatotoxicity/HSOS Hemorrhagic cystitis, nephrotoxicity electrolyte imbalances cardiotoxicity, fibrosis pneumonitis infertility alopecia erythema headaches/AMS 2ndary malignancy nasal congestion conjunctivitis Carboplatin - correct answer A/L/T N/V, mucos/stomatitis diarrhea, constipation nephrotoxicity, electrolyte imbalances dermatitis, alopecia hypersensitivity...

Heart: 5 Possible Drugs Correct Answer: Doxorubicin Daunorubicin Idarubicin Mitoxantrone Cyclophosphamide Mood: 1 Possible Drug Class Correct Answer: Corticosteroids Neurotoxicity: 3 Possible Drugs Correct Answer: Vincristine Nelarabine Ifosfamide Ototoxicity: 2 Possible Drugs 2 Correct Answer: Carboplatin Cisplatin Pulmonary Edema/Capillary Leak: 2 Possible Drugs Correct Answer: Clofarabine Cytarabine Diarrhea: Main Drug Correct Answer: Irinotecan Pulmonary Fibrosis: 1 Poss...

What type of transplants commonly have PTLD as a secondary malignancy? - ANSWER-Allo HSCT with T-cell depleted graft Therapies associated with therapy-related acute leukemia and MDS - ANSWER-alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , radiation, topoisomerase II inhibitors (eg. doxorubicin, etoposide, mitoxantrone) Genetic predispositions that increase risk of primary and secondary cancers - ANSWER-neurofibromatosis type 1, Fanconi anemia Risk factors for PTLD ...

vesicants - ANSWERbleomycin, carmustine, cisplatin, daunorubicin, doxorubicin, etposide, idarubicin, melphalan, taxol, vincristine cisplatin antidote - ANSWERsodium thiosulfate doxorubicin antidote - ANSWERDexrazoxane vincristine antidote - ANSWERhyaluronidase Alkylating agents - ANSWERbusulfan, cytoxan, melphalan, ifosfamide, carmustine; cell cycle non-specific; affects heme, GI, reproductive antimetabolites - ANSWERmethotrexate, 5-FU, cytarabine, gemcitabine, fludarabine; cell cycle speci...

when chemo is used before primary treatment (surgery) to reduce the size of a tumor Correct Answer: neoadjuvant therapy neoadjuvant therapy is common for what 2 kind of cancers? Correct Answer: colon and breast when chemo is used after primary (surgery, radiation) Correct Answer: adjuvant induction Correct Answer: start of chemo consolidation Correct Answer: testing labs and such after chemo myeloblation Correct Answer: destroying the bone marrow in order to a transplant for leukemias...

BMTCN Review Chapter 4 - Transplant Preparative Regimens, Cellular Infusion, Acute Complications, and EngraftmentTRANSPLANT PREP REGIMENS - correct answer Treatment leading up to transplant Acronyms: Ara-C BCNU BU Cy DLT SCT TBI - correct answer Cytarabine Carmustine Busulfan Cyclophosphamide Dose limiting toxicity DStem cell transplant Total body irradiation Induction chemotherapy - correct answer The first treatment given for a disease. It is often part of a standard set of ...

What type of transplants commonly have PTLD as a secondary malignancy? - ️️Allo HSCT with T-cell depleted graft Therapies associated with therapy-related acute leukemia and MDS - ️️alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , radiation, topoisomerase II inhibitors (eg. doxorubicin, etoposide, mitoxantrone) Genetic predispositions that increase risk of primary and secondary cancers - ️️neurofibromatosis type 1, Fanconi anemia Risk factors for PTLD -...

vesicants bleomycin, carmustine, cisplatin, daunorubicin, doxorubicin, etposide, idarubicin, melphalan, taxol, vincristine cisplatin antidote sodium thiosulfate doxorubicin antidote Dexrazoxane vincristine antidote hyaluronidase Alkylating agents busulfan, cytoxan, melphalan, ifosfamide, carmustine; cell cycle non-specific; affects heme, GI, reproductive antimetabolites methotrexate, 5-FU, cytarabine, gemcitabine, fludarabine; cell cycle specific, affect counts & GI platinum co...