Clonal selection - Study guides, Class notes & Summaries

MIC 205 FINAL EXAM 2024 WITH 100% CORRECT ANSWERS If you stepped on a rusty nail, which bacteria would most likely be the cause? - correct answer Tetanus, botulism Put these events in correct order for humoral immunity 1. clonal selection 2. formation of memory B cells 3. B cell activation 4. formation of plasma B cells 5. immunological memory - correct answer 3, 1, 4, 2, 5 DiGeorge Syndrom causes... - correct answer T cell deficiency and hypocalcemia What age do you have the...

Why do we need immunological tolerance? ~~> This allows us to get random generation of the repertoire of BCR and TCR This means self-reactive specificities will be made Without tolerance, we will get self destruction How do lymphocytes become tolerant? ~~> Central tolerance - they encounter antigens in the central lymphoid organs when they are immature Peripheral tolerance - they encounter antigens in the peripheral tissues in the absence of other necessary signals What is t...

QUIZ QUESTION: In an example of inflammation-mediated antibody damage to cells, Ig binds to self antigen on epithelial cells → complement binds Ig and is activated → pro inflammatory fragments of complement proteins are produced → the fragments bind to vessel walls → neutrophils move out of vessels → neutrophils bind to ____________ via receptors → neutrophils are triggered to release granules that damage cells. 1. complement proteins 2. Ig Fc portion 3. infected cells 4. sel...

UAMS Immunology Final Exam Review 2024. Substances that induce an immune response. ___________ can be harmful or harmless substances. Antigen Epitope Antibody binding site; single antigen site Antibody Glycoprotein; made in response to an antigen. Aka immunoglobulin Exposure to an antigen that causes an immune response. Immunization (Vaccination) FIRST LINE OF DEFENSE: -Antigen Non-specific -Rapid Response (minutes) -No Memory -Always present in healthy individuals Natural Immun...

Tuberculosis is an infectious disease that affects humans. It is caused by a pathogen Which of the following plant diseases is caused by the same type of pathogen that causes tuberculosis in humans? A black sigatoka in bananas B 'mosaic' leaf discolouration in tobacco plants C ring rot in tomatoes D late blight in potatoes - Answer C Fig. 25.1 shows the concentration of antibodies in a patient's bloodstream following a vaccination against a common pathogen and subsequent inf...

UAMS Immunology Final Exam Review 2024. Substances that induce an immune response. ___________ can be harmful or harmless substances. Antigen Epitope Antibody binding site; single antigen site Antibody Glycoprotein; made in response to an antigen. Aka immunoglobulin Exposure to an antigen that causes an immune response. Immunization (Vaccination) FIRST LINE OF DEFENSE: -Antigen Non-specific -Rapid Response (minutes) -No Memory -Always present in healthy individuals Natural Immuni...

What must an effective immune response do? (4 things) ~~> Be able to recognise and respond to invading pathogen Not over-react to to benign or self Be able to direct different effector mechanisms against different pathogens Links innate and adaptive responses What is adaptive immunity? (3 details) ~~> It is induced by exposure to a PARTICULAR infection, it has a high degree of specificity. It exhibits memory What is the clonal selection theory? Why? 2 | P a g e | © copyright ...

UAMS Immunology Final Exam Review 2024. Substances that induce an immune response. ___________ can be harmful or harmless substances. Antigen Epitope Antibody binding site; single antigen site Antibody Glycoprotein; made in response to an antigen. Aka immunoglobulin Exposure to an antigen that causes an immune response. Immunization (Vaccination) FIRST LINE OF DEFENSE: -Antigen Non-specific -Rapid Response (minutes) -No Memory -Always present in healthy individuals Natural Immunit...

Are B and T lymphocytes part of the adaptive or innate immune response? ~~> Adaptive it is the immune memory evolved over time What is the clonal selection theory? ~~> Immature lymphocytes that could self find are destroyed Mature naive lymphocytes are mature until they are exposed to antigens What are the two types of B receptor? ~~> Membrane bound And released from membrane they are known as antibodies T cell receptors are only membrane bound and are formed of what hete...

If you stepped on a rusty nail, which bacteria would most likely be the cause? CORRECT ANSWER Tetanus, botulism Put these events in correct order for humoral immunity 1. clonal selection 2. formation of memory B cells 3. B cell activation 4. formation of plasma B cells 5. immunological memory CORRECT ANSWER 3, 1, 4, 2, 5 DiGeorge Syndrom causes... CORRECT ANSWER T cell deficiency and hypocalcemia What age do you have the best immunity CORRECT ANSWER 10 The picture for ELISA t...