Wayland Baptist University
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QUESTIONS AND ANSWERS STUDY GUIDE
QUESTIONS AND ANSWER EXAM GUIDE
NR 566 Week 1 Notes Ch. 21, 33, & 41 
Chapter 21: Drugs Affecting the Endocrine System 
Pharmacokinetics 
 Absorption and Distribution 
o All oral bisphosphonates potentially cause esophagitis and gastric irritation 
o Absorption and bioavailability of oral doses are significantly reduced by the presence of food in 
the gut or other preparations containing divalent cations. 
o To enhance absorption, the patient takes the drug with 8 oz of water, No other food or drink 
should be ingested, and...
NR566 Week 1 Study Outline 
Many questions are written to assess your clinical application of the material from the textbook, in real-world scenarios. 
Chapter 21: Drugs Affecting the Endocrine System 
•	Know the pharmacodynamics, pharmacotherapeutics clinical use, drug interactions and adverse drug reactions for: 
 o Biphosphonates The remodeling cycle is initiated by osteoclastic activity. In response to microfractures and other damage associated with normal wear and tear, osteoclas...
In your initial post, respond to the following scenario (Hint: use the pharmgkb website to guide your responses): 
 
Before initiating abacavir, an anti-retroviral, for a newly diagnosed HIV positive patient the nurse practitioner orders HLA-B*5701 allele genetic testing. The test confirms that the patient carries the HLA-B*5701 allele. 
* Describe what these results mean. 
* Should the nurse practitioner prescribe abacavir in this case? If not, state why. 
A patient is prescribed antiplate...