P450 system - Study guides, Class notes & Summaries

TEST BANK FOR DAVIS'S DRUG GUIDE FOR NURSES 19TH EDITION BY VALLERAND, SANOSKI Latest Verified Review 2024 Practice Questions and Answers for Exam Preparation, 100% Correct with Explanations, Highly Recommended, Download to Score A+ Table Of Contents HOW TO USE DAVIS’S DRUG GUIDE FOR NURSES EVIDENCE-BASED PRACTICE AND PHARMACOTHERAPEUTICS: Implications for Nurses PHARMACOGENOMICS MEDICATION ERRORS: Improving Practices and Patient Safety DETECTING AND MANAGING ADVERSE DRUG REACTIONS OVE...

Prodrug An inactive drug dosage form that is converted to an active metabolite by various biochemical reactions once it is inside the body. -Cytochrome P450 -Ex. Aspirin, psilocybin, heroin Bioavailability the rate at and the extent to which a nutrient is absorbed and used -Affected by route of administration and drug dosage -Drug clearance (rate drug leaves circulation) -Steady state concentration -Affected by chemical stability, solubility, and first pass Steady state (of a drug) stab...

1. During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? ANS 1st trimester (fetus most at risk d/t rapid growth) 2. What is BEERS criteria? ANS Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides 3. What is the CYP450 (cytochrome P450) ANS liver enzyme system where medica- tions are metabolized, can either be inducers or inhibitors and create drug-drug interactions 4. CYP45...

What should the PMHNP consider when prescribing chemical restraints? - -allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - No. The client has been court-ordered to take the prescribed medications and the standing order for chemical re...

NR546 / NR 546 ACTUAL MIDTERM EXAM 2023 QUESTIONS AND ANSWERS What should the PMHNP consider when prescribing chemical restraints? - Answer-- allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - Answer-No. The client has been court-ordered t...

Prodrug correct answer: An inactive drug dosage form that is converted to an active metabolite by various biochemical reactions once it is inside the body. -Cytochrome P450 -Ex. Aspirin, psilocybin, heroin Bioavailability correct answer: the rate at and the extent to which a nutrient is absorbed and used -Affected by route of administration and drug dosage -Drug clearance (rate drug leaves circulation) -Steady state concentration -Affected by chemical stability, solubility, and fir...

NRNP 6566 WEEK1-5 Midterm Latest (Answered) 100% Verified Describe cytochrome p450 system Answer: Cytochrome p450 system is a series of enzymes used to metabolize medications Inhibitors Answer: block metabolic activity from one or more CYP450 enzymes Inducers Answer: increase CYP450 enzyme activity by increasing enzyme synthesis Describe effect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound Answer: Albumin is the plasma...

NURS 6630 MIDTERM EXAM TEST BANK QUESTIONS ANDA ANSWERS GRADED ARATED 5 STAR 2023/2024 Why is the cytochrome P450 enzyme system of significance to the PMHNP? Answer: B. The bioavailability of the medication after it passes through the stomach and liver can be altered. 1 out of 1 points It is important for the PMHNP to recognize differences in pharmacokinetics to safely prescribe and monitor medications. Which of the following statements does the competent PMHNP identify as true? Answer...

Describe cytochrome p450 system - CORRECT ANSWER Cytochrome p450 system is a series of enzymes used to metabolize medications Inhibitors - CORRECT ANSWER block metabolic activity from one or more CYP450 enzymes Inducers - CORRECT ANSWER increase CYP450 enzyme activity by increasing enzyme synthesis Describe effect on low and high albumin levels on active drug levels especially for drugs that are highly protein bound - CORRECT ANSWER Albumin is the plasma protein with the g...

NR546 Midterm Exam Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - Answer-No. The client has been court-ordered to take the prescribed medications and the standing order for chemical restraints is approved. The PMHNP and other staff are not liable if the patient has an allergic reaction or adverse side effects. How does reviewing the genetic makeup of a client help guide the PMHNP in selec...