Heme synthesis - Study guides, Class notes & Summaries

NURS 8022 Exam 2 (Studyguide transformed into flashcards) Qs&As A+ Review Hematopoiesis -Process of blood cell production in adult bone marrow or the liver and/or spleen of the fetus Two stages ▪ Mitosis (proliferation) ▪ Maturation (differentiation) Primary site of hematopoietic stem cells -Bone marrow ("myeloid tissue") Difference between red and yellow bone marrow -Red marrow produces RBCs, yellow marrow does not produce RBCs Active bone marrow sites -pelvic bones...

ASCP Board of Certification MLT Computer Adaptive Practice Test With Complete Solutions| Score Guide| Graded A+ This is a practice test with 100 question from all areas (Blood bank, Chemistry, Hematology, Immunology, Lab Operations, Microbiology, & Urinalysis & other body Fluids) Disorders in which coarse basophilic stippling can be seen are in all of the following except? A: Polycythemia B: Thalassemia C: Disorders of abnormal heme synthesis D: Lead poisoning **This is a Level 5 Q...

NRNP 6566 MidtermStudy Guide NRNP 6566 Mid-term Study Guide Week 1 to 5 Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as ...

Protons are pumped by mitochondria during active electron transport correct answers outside the inner mitochondrial membrane. As electrons from NADH pass through the electron transport system, correct answers protons are pumped across the mitochondrial membrane to create a pH gradient. The first enzyme in the electron transport system is referred to as complex I, otherwise known as correct answers NADH-ubiquinone oxidoreductase. Which statement is true of the mitochondrial electron tran...

Protons are pumped by mitochondria during active electron transport correct answers outside the inner mitochondrial membrane. As electrons from NADH pass through the electron transport system, correct answers protons are pumped across the mitochondrial membrane to create a pH gradient. The first enzyme in the electron transport system is referred to as complex I, otherwise known as correct answers NADH-ubiquinone oxidoreductase. Which statement is true of the mitochondrial electron tran...

What is hemoglobin composed of? - 4 heme, 4 iron, 4 globins What disorder does a defect in heme synthesis lead to? - Porphyria Porphyria - Deficiency in the enzymes of the porphyrin pathway leads to insufficient production of heme. The principal problem in these deficiencies is the accumulation of porphyrins, the heme precursors, which are toxic to tissue in high concentrations. What is methemoglobin? -Methemoglobin is a form of hemoglobin that contains ferric [Fe3+] iron and has a decreas...

The light-colored zone adjacent to the nucleus in a plasmacyte is the: A. ribosome B. chromatin C. mitochondria D. Golgi area - D. Golgi area The majority of the iron in an adult is found as a constituent of: A. hemoglobin B. hemosiderin C. myoglobin D. transferrin - A. hemoglobin The main function of the hexose monophosphate shunt in the erythrocyte is to: A. reglate the level of 2,3-DPG B. provide reduced glutathione to prevent oxidation of hemoglobin C. prevent the reduction of h...

USMLE STEP 1 - UWORLD HIGH YIELD EXAM | QUESTIONS AND ANSWERS | 2024 What are the two major microtubular motor proteins? Which does anterograde axonal transport, which does retrograde axonal transport? - Kinesin, Dynein Kinesin: Anterograde Dynein: Retrograde` What do you think, immunologically speaking, when you see someone with recurrent Neisseria infections? - Inability to form the membrane attack (MAC) complex this is a common complement deficiency What is the defect in...

Porphyrin correct answer: Cyclic molecules formed by the linkage of 4 pyrole rings through methynl bridges. They bind metals tightly Name the 4 physiological roles of the HEME porphoryin correct answer: 1. Mitochondrial cytochrome: generate H+ gradient in ETC 2. Hemoglobin and Myoglobin: O2 transport in blood and muscle 3. Cytochrome P450 enzymes: metabolize fat soluble compounds. (CYP3A4) important in drug reactions 4. Catalase: antioxidant enzyme hydrolyzes H2O2 Where is Heme made...

What is hemoglobin composed of? - correct answer 4 heme, 4 iron, 4 globins What disorder does a defect in heme synthesis lead to? - correct answer porphyria What is the function of the enzyme methemoglobin-cytochrome C reductase in a red blood cell? - correct answer to keep iron in the ferrous state Which hemoglobin has a 200 times greater binding capacity for the hemoglobin molecule than oxygen? - correct answer carboxyhemoglobin What product is formed when ferrous iron of h...