Mesolimbic pathway - Study guides, Class notes & Summaries
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Maryville Psychopharmacology, Exam 1 Review
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How many dopamine pathways in the brain? - Answer - 5 but only 4 associated with schizophrenia 
 
Nigrostriatal Dopamine Pathway controls - Answer - motor function and movement (part of EP NS) 
 
Nigrostriatal Dopamine Pathway dopamine excess - Answer - Hyperkinetic movements such as tics/dyskinesias 
 
mesolimbic dopamine pathway controls - Answer - Pleasure, reward, euphoria of drug abuse and reinforcing behavior 
 
Mesolimbic dopamine pathway excess - Answer - delusions and hallucinations - p...
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Exam 1: NURS 660/ NURS660 (Latest 2024/ 2025 Update) Psychopharmacology and Advanced Mental Health Review | Qs & As| 100% Correct| Grade A (Verified Answers)- Maryville
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Exam 1: NURS 660/ NURS660 (Latest 2024/ 2025 Update) Psychopharmacology and Advanced Mental Health Review | Qs & As| 100% Correct| Grade A (Verified Answers)- Maryville 
 
 
Q: What is the black box warning of Clozapine 
 
 
Answer: 
Agranulocytosis 
 
 
 
Q: What is the most common side effect of clozapine 
 
 
Answer: 
sedation 
 
 
 
Q: What labs need to be done before starting clients on antipsychotic medications? 
 
 
Answer: 
fasting lipid panel, fasting glucose, weight, bp 
 
 
 
Q: When ...
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NURS 660 SUM 2023 Exam 1 dopamine, serotonin, abnl movements, questions with complete solutions
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dopamine hypothesis correct answer: the theory that schizophrenia results from excessive activity of the neurotransmitter dopamine 
 
What is the path of dopamine suppression by 5-HT? correct answer: 5-HT2A antagonism by atypical antipsychotics decrease serotonin release, thereby stimulating downstream dopamine. Increased dopamine reduces glutamate which inhibits release of inhibitory GABA (inhibits dopamine) 
 
Mesolimbic dopamine hypothesis: Hyperactivity of dopamine neurons in the mesolimbi...
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NURS 660 Exam1 LATEST UPDATE 2023 QUESTIONS AND EXPLAINED ANSWERS|AGRADE
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NURS 660 Exam1 LATEST UPDATE 2023 
QUESTIONS AND EXPLAINED 
ANSWERS|AGRADE 
1. Identify the emerging neurobiological hypothesis of schizophrenia. 
o The hypothesis: (focus on the most detail with the Dopamine Theory) 
 The only pharmacological treatment that we have are dopamine (D2 
receptors) and serotonin (5HT2A) 
 Dopamine Theory 
▪ Hyperactive dopamine at D2 receptors in the mesolimbic 
pathway 
In the mesolimbic pathway is responsible for the positive 
symptoms; the hypoactivity is res...
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Final Exam: NR546/ NR 546 (Latest 2024/ 2025 Update) Psychopharmacology for the PMHNP Review -Questions and Verified Answers -100% Correct-Grade A-Chamberlain
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Final Exam: NR546/ NR 546 (Latest 2024/ 2025 Update) Psychopharmacology for the PMHNP Review -Questions and Verified Answers -100% Correct-Grade A-Chamberlain 
 
Q: Hallucinogenic intoxication 
 
 
Answer: 
 pupillary dilation, tachycardia, sweating, palpitations, blurred vision, tremors, incoordination 
Can be perceived as a panic attack and often called a bad trip. 
Can experience an acute state of confusion (delirium) where the abuser is disoriented and agitated. 
 
 
 
Q: Disulfiram 
 
 
An...
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Exam (elaborations) NURS 660
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dopamine hypothesis - ANSWER the theory that schizophrenia results from excessive 
activity of the neurotransmitter dopamine 
dopamine hypothesis- nigrostriatal pathway - ANSWER The nigrostriatal dopamine 
pathway that projects from the substantia nigra to the basal ganglia or striatum, is part 
of the extrapyramidal nervous system and controls motor function and movement. 
Mesolimbic dopamine hypothesis: Hyperactivity of dopamine neurons in the mesolimbic 
dopamine pathway cause what sympto...
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Ninja PRITE Part 1 QUESTIONS & ANSWERS 100% CORERCT!!
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26 y.o. w/HA and R-hand clumsiness for weeks. Exam 
shows difficulty w/rapid alternating movements of 
hand, overt intention tremor on finger-to-nose, and 
mildly dysmetric finger tamping. CNS intact and no 
papilledema. Where will damage show on MRI? - ANSWERCEREBELLUM 
 
Mesolimbic DA pathway includes which structure? - ANSWERVENTRAL STRIATUM 
 
In addiction, dopaminergic neurons project to nucleus 
accumbens. Cell bodies of these neurons reside in 
which area of brain? - ANSWERVENTRAL T...
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NR 546 / NR546 Actual Final Exam 2024/2025 Prediction 70 Questions (All Correct Answers, Already Graded A)
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Which of the following is considered the pleasure center of the brain? 
A. Cortico-striatal-thalamic-cortical loop 
B. Mesolimbic dopamine pathway 
C. Mesocortical dopamine pathway 
D. None of the above - B. Mesolimbic dopamine pathway 
The reactive reward system signals the immediate prospect of pleasure or pain and triggers drug-seeking behavior. 
A. True 
B. False - A. True 
What role does the amygdala play in substance abuse? 
A. Releases phasic bursts of dopamine to the nucleus accumbens wh...
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NR 546 / NR546 Actual Final Exam 2024 / 2025 Prediction Questions (All Correct Answers, Already Graded A)
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Which of the following is considered the pleasure center of the brain? 
A. Cortico-striatal-thalamic-cortical loop 
B. Mesolimbic dopamine pathway 
C. Mesocortical dopamine pathway 
D. None of the above - B. Mesolimbic dopamine pathway 
The reactive reward system signals the immediate prospect of pleasure or pain and triggers drug-seeking behavior. 
A. True 
B. False - A. True 
What role does the amygdala play in substance abuse? 
A. Releases phasic bursts of dopamine to the nucleus accumbens wh...
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Exam 4: NURS660/ NURS 660 (NEW 2023/ 2024) Psychopharmacology and Advanced Mental Health Exam |Grade A | Questions and Verified Answers - Maryville
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Exam 4: NURS660/ NURS 660 (NEW 2023/ 
2024) Psychopharmacology and Advanced 
Mental Health Exam |Grade A | Questions 
and Verified Answers - Maryville 
Question 
 Why do some people with ADHD abuse cocaine? What MOA does cocaine affect the same as 
methylphenidate? 
 
 
Answer: 
they have the same key binding site for the serotonin 2a receptor 
 
 
 
Question 
 MOA of naltrexone how does it help people come OFF alcohol? 
 
 
Answer: 
by blocking mu receptors to induce euphoria 
 
 
 
Quest...
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