Micr 270 - Study guides, Class notes & Summaries
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MICR 270 Exam with Questions and 100% Verified Answers
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Major Histocompatibility Complex (MHC) - Answer Group of genes that code for 
proteins found on the surfaces of cells that help the immune system recognize foreign 
substances. 
memory cells - Answer General term for lymphocytes that are responsible for 
immunological memory and protective immunity. 
Monocytes - Answer An agranular leukocyte that is able to migrate into tissues and 
transform into a macrophage.
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What are the goals of the immune system? - Answer Discriminate: Recognize self from 
non-self 
Eliminate: Destroy non-self (pathogen) and altered self cells (cancer) 
- Occurs through the ability of immune cells to initiate immune response 
- Antigen enters → recognized → effector cells are activated → elimination
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TLR signalling - Answer TLRS recognize through ramps or damps, then the engulfed 
pathogen is presented to the MHC and the production of co-stimulatory molecules is 
increased, and an immunocompetent naive T cell binds to the MHC and can initiate an 
adaptive IR. 
Humoral Activation - Answer Activated and differentiated TH2 cells activate B cells and 
induce their differentiation into plasmocytes. Plasmocytes then secrete a large number 
of antibodies for the invading antigen.
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Once a pathogen is eliminated, the vast majority of lymphocytes undergo 
_______________ the immune response gradually increases/declines - Answer 
apoptosis 
declines 
What happens to the cells that survive the contraction phase? - Answer They become 
memory cells
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