Lineweaver burk plot - Study guides, Class notes & Summaries
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USMLE 1 PharmEnzyme/Pharmacokinetics/Pharmacody namics 2022
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what is Km - ANSWER-concentration of substrate at 1/2 Vmax 
what is Km inversely related to - ANSWER-the affinity of the enzyme for its substrate 
(low Km=high affinity & high Km=low affinity) 
what is Vmax directly proportional to - ANSWER-enzyme concentration 
most enzymes follow what kind of kinetics - ANSWER-Michaelis-Menten kinetics (line 
up and then it flattens out, hyperbolic) 
if an enzymatic rxn shows a sigmoid curve what does that indicate - ANSWERcooperative kinetics (hemoglobin) 
do...
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NBME Pharmacology Questions & answers 2022
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Define Km in MM kinetics: - ANSWER-The concentration of substrate [S] at which 1/2 
Vmax is reached 
Km is _________ related to affinity of the enzyme for its substrate - ANSWER-inversely 
Vmax is directly proportional to what? - ANSWER-to the enzyme concentration 
What characterizes MM kinetics? - ANSWER-a hyperbolic curve when Vmax is plotted 
against [S]. Most enzymes follow MM kinetics. 
Enzymatic reactions demonstrated a sigmoid curve usually denote: - ANSWERcooperative binding / kinetics, ...
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BCH 361 Ch. 7 TEST QUESTIONS WITH CORRECT ANSWERS
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BCH 361 Ch. 7 TEST QUESTIONS WITH CORRECT ANSWERS 
Match the condition w/ the statement that describe it. This condition will result in the highest rate. 
A.	[S]= 10Km 
B.	[S]= Km 
C.	[S]= 0.1Km - Answer-A 
 
Match the condition w/ the statement that describe it. Doubling [S] will have little effect on the rate. 
A.	[S]= 10Km 
B.	[S]= Km 
C.	[S]= 0.1Km - Answer-A 
 
Match the condition w/ the statement that describe it. About 90% of the active sites are occupies by substrate 
A.	[S]= 10Km 
B.	[...
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BCH 369 CHAPTER 7 TEST QUESTIONS WITH ANSWERS ALL REVISED AND UPDATED
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BCH 369 CHAPTER 7 TEST QUESTIONS WITH ANSWERS ALL REVISED AND UPDATED 
Michaelis-Menten equation - Answer-A mathematical expression that describes the activity of an enzyme in terms of the substrate concentration ([S]), the enzyme's maximal velocity (Vmax), and its michaelis constant (Km): Vo = Vmax [S]/(Km + [S]). 
 
catalytic constant (Kcat) - Answer-The ratio of the maximal velocity (Vmax) of an enzyme-catalyzed reaction to the enzyme concentration. Also called a turnover number. 
 
Turnover...
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PHARMACOLOGY EXAM WITH COMPLETE SOLUTIONS UPDATED 2023|2024 RATED A+
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Step 1 Express 2021 workbook: PHARMACOLOGY page 1 
© First Aid for the USMLE Step 1, 2021 edition 
Pharmacology 
PHARMACOKINETICS AND PHARMACODYNAMICS 
1. Competitive inhibitors ________ (do/do not) resemble the substrate, but noncompetitive inhibitors 
__________ (do/do not) resemble the substrate. (p 232) 
2. Km is inversely related to the ______________ of the enzyme for its substrate. (p 232) 
3. True or False: In enzyme kinetics, the lower the Km , the higher the affinity. (p 232) ________...
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AAMC 4 Bio question with complete solution 2023/2024
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AAMC 4 Bio question with complete solution 2023/2024Most cytochrome P450 enzymes alter the activity of drugs by: - correct answer oxidizing them 
*Cytochrome P450 acts as monooxygenases, where an oxygen atom is inserted into a substrate (the drug of interest), thereby resulting in the oxidation of the substrate. 
- MISSED 
- was between reduced and oxidized; remember it is a monoxygenase 
 
During phosphorylation of STAT5b proteins, phosphate groups are exchanged for what atoms on tyrosine resi...
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150 Biochemistry Exam 1 practice questions with correct answers. Rated A. 2022/2023 updates
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150 Biochemistry Exam 1 practice questions with correct answers. Rated A. 2022/2023 updates 
Document Content and Description Below 
What type of isomers are glucose and fructose? >>> structural isomers What type of isomers are glucose and galactose >>> stereoisomers What are the strongest intermolecular interactions between phen ylalanine and alanine? >>> hydrophobic What are the strongest intermolecular interactions between aspartate and lysine >>> ionic bon...
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Biochemistry Final Exam Practice 63 Questions with Verified Answers,100% CORRECT
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Biochemistry Final Exam Practice 63 Questions with Verified Answers 
 
The central dogma of molecular biology teaches us that: 
a. RNA replicates itself and DNA is translated into protein 
b. RNA is typically the genetic material 
c. RNA contains information, which is translated into amino acid sequences 
d. Proteins are not needed to replicate DNA or transcribe RNA 
e. RNA is made of the same monomers as DNA - CORRECT ANSWER c. RNA contains information, which is translated into amino acid sequ...
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171 Biochemistry Exam 1 Questions with correct answers 2023/2024
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171 Biochemistry Exam 1 Questions with correct answers 2023/ Biochemistry Exam 1 Questions with correct answers 2023/2024 
Myoglobin >>What protein is used for storage? 
 Myoglobin 
 Hemoglobin 
 Collagen 
 Transferrin 
 
It's a covalent interaction >>What is NOT TRUE of antibodies with respect to protection? 
 It is a covalent interaction 
 It's a noncovalent interaction; hydrogen bonding 
 
Aspartic acid pKa=3.9 >>What is the amino acid that would dissociate a proton and ma...
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150 Biochemistry Exam 1 practice questions with correct answers. Rated A. 2022/2023 updates
- Exam (elaborations) • 9 pages • 2023
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What type of isomers are glucose and fructose? >>> structural isomers 
What type of isomers are glucose and galactose >>> stereoisomers 
What are the strongest intermolecular interactions between phenylalanine and alanine? 
>>> hydrophobic 
What are the strongest intermolecular interactions between aspartate and lysine >>> 
ionic bond 
What are the strongest intermolecular interactions between serine and glutamine >>> 
hydrogen bond 
What are the stro...
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